BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 35543151)

  • 1. TRAP1 regulates the response of colorectal cancer cells to hypoxia and inhibits ribosome biogenesis under conditions of oxygen deprivation.
    Bruno G; Li Bergolis V; Piscazzi A; Crispo F; Condelli V; Zoppoli P; Maddalena F; Pietrafesa M; Giordano G; Matassa DS; Esposito F; Landriscina M
    Int J Oncol; 2022 Jun; 60(6):. PubMed ID: 35543151
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas.
    Maddalena F; Condelli V; Matassa DS; Pacelli C; Scrima R; Lettini G; Li Bergolis V; Pietrafesa M; Crispo F; Piscazzi A; Storto G; Capitanio N; Esposito F; Landriscina M
    Mol Oncol; 2020 Dec; 14(12):3030-3047. PubMed ID: 33025742
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia.
    Laquatra C; Sanchez-Martin C; Dinarello A; Cannino G; Minervini G; Moroni E; Schiavone M; Tosatto S; Argenton F; Colombo G; Bernardi P; Masgras I; Rasola A
    Cell Death Dis; 2021 May; 12(5):434. PubMed ID: 33934112
    [TBL] [Abstract][Full Text] [Related]  

  • 4. C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway.
    Kataria N; Martinez CA; Kerr B; Zaiter SS; Morgan M; McAlpine SR; Cook KM
    Cell Physiol Biochem; 2019; 53(3):480-495. PubMed ID: 31486323
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
    Matassa DS; Amoroso MR; Agliarulo I; Maddalena F; Sisinni L; Paladino S; Romano S; Romano MF; Sagar V; Loreni F; Landriscina M; Esposito F
    Cell Death Dis; 2013 Oct; 4(10):e851. PubMed ID: 24113185
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
    Ban HS; Kim BK; Lee H; Kim HM; Harmalkar D; Nam M; Park SK; Lee K; Park JT; Kim I; Lee K; Hwang GS; Won M
    Cell Death Dis; 2017 Jun; 8(6):e2843. PubMed ID: 28569777
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.
    Dong S; Liang S; Cheng Z; Zhang X; Luo L; Li L; Zhang W; Li S; Xu Q; Zhong M; Zhu J; Zhang G; Hu S
    J Exp Clin Cancer Res; 2022 Jan; 41(1):15. PubMed ID: 34998404
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transglutaminase 2 reprogramming of glucose metabolism in mammary epithelial cells via activation of inflammatory signaling pathways.
    Kumar S; Donti TR; Agnihotri N; Mehta K
    Int J Cancer; 2014 Jun; 134(12):2798-807. PubMed ID: 24477458
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells.
    Huang CY; Kuo WT; Huang YC; Lee TC; Yu LC
    Cell Death Dis; 2013 May; 4(5):e622. PubMed ID: 23640464
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors.
    Leung E; Cairns RA; Chaudary N; Vellanki RN; Kalliomaki T; Moriyama EH; Mujcic H; Wilson BC; Wouters BG; Hill R; Milosevic M
    BMC Cancer; 2017 Jun; 17(1):418. PubMed ID: 28619042
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TRAP1 Chaperones the Metabolic Switch in Cancer.
    Wengert LA; Backe SJ; Bourboulia D; Mollapour M; Woodford MR
    Biomolecules; 2022 Jun; 12(6):. PubMed ID: 35740911
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment.
    Frolova O; Samudio I; Benito JM; Jacamo R; Kornblau SM; Markovic A; Schober W; Lu H; Qiu YH; Buglio D; McQueen T; Pierce S; Shpall E; Konoplev S; Thomas D; Kantarjian H; Lock R; Andreeff M; Konopleva M
    Cancer Biol Ther; 2012 Aug; 13(10):858-70. PubMed ID: 22785211
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase.
    Sciacovelli M; Guzzo G; Morello V; Frezza C; Zheng L; Nannini N; Calabrese F; Laudiero G; Esposito F; Landriscina M; Defilippi P; Bernardi P; Rasola A
    Cell Metab; 2013 Jun; 17(6):988-999. PubMed ID: 23747254
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia induces glucose uptake and metabolism of adipose‑derived stem cells.
    Park HS; Kim JH; Sun BK; Song SU; Suh W; Sung JH
    Mol Med Rep; 2016 Nov; 14(5):4706-4714. PubMed ID: 27748854
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TNFα and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells.
    Straus DS
    Mol Cancer; 2013 Jul; 12():78. PubMed ID: 23866118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway.
    Luo F; Liu X; Yan N; Li S; Cao G; Cheng Q; Xia Q; Wang H
    BMC Cancer; 2006 Jan; 6():26. PubMed ID: 16438736
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of TRAP1 Accelerates the DNA Damage Response, Activation of the Heat Shock Response and Metabolic Reprogramming in Colon Cancer Cells.
    Bhasin N; Dabral P; Senavirathna L; Pan S; Chen R
    Front Biosci (Landmark Ed); 2023 Sep; 28(9):227. PubMed ID: 37796715
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
    Zeng L; Zhou HY; Tang NN; Zhang WF; He GJ; Hao B; Feng YD; Zhu H
    World J Gastroenterol; 2016 May; 22(20):4868-80. PubMed ID: 27239113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.
    Katschinski DM; Le L; Schindler SG; Thomas T; Voss AK; Wenger RH
    Cell Physiol Biochem; 2004; 14(4-6):351-60. PubMed ID: 15319539
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma.
    Condelli V; Maddalena F; Sisinni L; Lettini G; Matassa DS; Piscazzi A; Palladino G; Amoroso MR; Esposito F; Landriscina M
    Oncotarget; 2015 Sep; 6(26):22298-309. PubMed ID: 26084290
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.