BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 35545699)

  • 1. Degron masking outlines degronons, co-degrading functional modules in the proteome.
    Guharoy M; Lazar T; Macossay-Castillo M; Tompa P
    Commun Biol; 2022 May; 5(1):445. PubMed ID: 35545699
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning.
    Hou C; Li Y; Wang M; Wu H; Li T
    BMC Biol; 2022 Jul; 20(1):162. PubMed ID: 35836176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons.
    Koren I; Timms RT; Kula T; Xu Q; Li MZ; Elledge SJ
    Cell; 2018 Jun; 173(7):1622-1635.e14. PubMed ID: 29779948
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A comparative analysis of the ubiquitination kinetics of multiple degrons to identify an ideal targeting sequence for a proteasome reporter.
    Melvin AT; Woss GS; Park JH; Dumberger LD; Waters ML; Allbritton NL
    PLoS One; 2013; 8(10):e78082. PubMed ID: 24205101
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System.
    Guharoy M; Bhowmick P; Tompa P
    J Biol Chem; 2016 Mar; 291(13):6723-31. PubMed ID: 26851277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DegronMD: Leveraging Evolutionary and Structural Features for Deciphering Protein-Targeted Degradation, Mutations, and Drug Response to Degrons.
    Xu H; Hu R; Zhao Z
    Mol Biol Evol; 2023 Dec; 40(12):. PubMed ID: 37992195
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Hunt for Degrons of the 26S Proteasome.
    Ella H; Reiss Y; Ravid T
    Biomolecules; 2019 Jun; 9(6):. PubMed ID: 31200568
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway.
    Yi SA; Sepic S; Schulman BA; Ordureau A; An H
    Mol Cell; 2024 Jun; 84(11):2166-2184.e9. PubMed ID: 38788716
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.
    Maurer MJ; Spear ED; Yu AT; Lee EJ; Shahzad S; Michaelis S
    G3 (Bethesda); 2016 Jul; 6(7):1853-66. PubMed ID: 27172186
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Building yeast libraries to dissect terminal degrons with fluorescent timers.
    Kong KE; Reinbold C; Knop M; Khmelinskii A
    Methods Enzymol; 2023; 686():297-319. PubMed ID: 37532405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system.
    Guharoy M; Bhowmick P; Sallam M; Tompa P
    Nat Commun; 2016 Jan; 7():10239. PubMed ID: 26732515
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase.
    Kong KE; Fischer B; Meurer M; Kats I; Li Z; Rühle F; Barry JD; Kirrmaier D; Chevyreva V; San Luis BJ; Costanzo M; Huber W; Andrews BJ; Boone C; Knop M; Khmelinskii A
    Mol Cell; 2021 Jun; 81(11):2460-2476.e11. PubMed ID: 33974913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Degrons in cancer.
    Mészáros B; Kumar M; Gibson TJ; Uyar B; Dosztányi Z
    Sci Signal; 2017 Mar; 10(470):. PubMed ID: 28292960
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HSP70-binding motifs function as protein quality control degrons.
    Abildgaard AB; Voutsinos V; Petersen SD; Larsen FB; Kampmeyer C; Johansson KE; Stein A; Ravid T; Andréasson C; Jensen MK; Lindorff-Larsen K; Hartmann-Petersen R
    Cell Mol Life Sci; 2023 Jan; 80(1):32. PubMed ID: 36609589
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tying up loose ends: the N-degron and C-degron pathways of protein degradation.
    Timms RT; Koren I
    Biochem Soc Trans; 2020 Aug; 48(4):1557-1567. PubMed ID: 32627813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recognition of substrate degrons by E3 ubiquitin ligases and modulation by small-molecule mimicry strategies.
    Lucas X; Ciulli A
    Curr Opin Struct Biol; 2017 Jun; 44():101-110. PubMed ID: 28130986
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cereblon neo-substrate binding mimics the recognition of the cyclic imide degron.
    Heim C; Spring AK; Kirchgäßner S; Schwarzer D; Hartmann MD
    Biochem Biophys Res Commun; 2023 Feb; 646():30-35. PubMed ID: 36701892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping.
    Zhang Z; Sie B; Chang A; Leng Y; Nardone C; Timms RT; Elledge SJ
    Mol Cell; 2023 Sep; 83(18):3377-3392.e6. PubMed ID: 37738965
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N/C-degron pathways and inhibitor development for PROTAC applications.
    Wu Z; Huang Y; Liu K; Min J
    Biochim Biophys Acta Gene Regul Mech; 2024 Mar; 1867(1):194952. PubMed ID: 37263341
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role and Fate of TCTP in Protein Degradative Pathways.
    Vidal M
    Results Probl Cell Differ; 2017; 64():137-148. PubMed ID: 29149406
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.