BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 35571990)

  • 1. Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo.
    Kohlmeyer JL; Kaemmer CA; Lingo JJ; Voigt E; Leidinger MR; McGivney GR; Scherer A; Koppenhafer SL; Gordon DJ; Breheny P; Meyerholz DK; Tanas MR; Dodd RD; Quelle DE
    Neurooncol Adv; 2022; 4(1):vdac047. PubMed ID: 35571990
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors.
    Kohlmeyer JL; Kaemmer CA; Pulliam C; Maharjan CK; Samayoa AM; Major HJ; Cornick KE; Knepper-Adrian V; Khanna R; Sieren JC; Leidinger MR; Meyerholz DK; Zamba KD; Weimer JM; Dodd RD; Darbro BW; Tanas MR; Quelle DE
    Clin Cancer Res; 2020 Jun; 26(12):2997-3011. PubMed ID: 32086342
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transposon Mutagenesis-Guided CRISPR/Cas9 Screening Strongly Implicates Dysregulation of Hippo/YAP Signaling in Malignant Peripheral Nerve Sheath Tumor Development.
    VĂ©lez-Reyes GL; Koes N; Ryu JH; Kaufmann G; Berner M; Weg MT; Wolf NK; Rathe SK; Ratner N; Moriarity BS; Largaespada DA
    Cancers (Basel); 2021 Mar; 13(7):. PubMed ID: 33808166
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combination therapies for MPNSTs targeting RABL6A-RB1 signaling.
    Kohlmeyer JL; Gordon DJ; Tanas MR; Dodd RD; Monga V; Darbro BW; Quelle DE
    Oncotarget; 2021 Jan; 12(1):10-14. PubMed ID: 33456709
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner.
    Kohlmeyer JL; Kaemmer CA; Umesalma S; Gourronc FA; Klingelhutz AJ; Quelle DE
    Int J Mol Sci; 2021 May; 22(10):. PubMed ID: 34065204
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genomic Status of
    Peacock JD; Pridgeon MG; Tovar EA; Essenburg CJ; Bowman M; Madaj Z; Koeman J; Boguslawski EA; Grit J; Dodd RD; Khachaturov V; Cardona DM; Chen M; Kirsch DG; Maina F; Dono R; Winn ME; Graveel CR; Steensma MR
    Cancer Res; 2018 Jul; 78(13):3672-3687. PubMed ID: 29720369
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors.
    Ki DH; He S; Rodig S; Look AT
    Oncogene; 2017 Feb; 36(8):1058-1068. PubMed ID: 27477693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST.
    Chung MH; Aimaier R; Yu Q; Li H; Li Y; Wei C; Gu Y; Wang W; Guo Z; Long M; Li Q; Wang Z
    Cell Oncol (Dordr); 2023 Oct; 46(5):1399-1413. PubMed ID: 37086345
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Malignant peripheral nerve sheath tumor: a comparison of grade, immunophenotype, and cell cycle/growth activation marker expression in sporadic and neurofibromatosis 1-related lesions.
    Zhou H; Coffin CM; Perkins SL; Tripp SR; Liew M; Viskochil DH
    Am J Surg Pathol; 2003 Oct; 27(10):1337-45. PubMed ID: 14508395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation.
    Hirbe AC; Dahiya S; Friedmann-Morvinski D; Verma IM; Clapp DW; Gutmann DH
    Oncotarget; 2016 Feb; 7(7):7403-14. PubMed ID: 26859681
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Confirmation of mutation landscape of NF1-associated malignant peripheral nerve sheath tumors.
    Sohier P; Luscan A; Lloyd A; Ashelford K; Laurendeau I; Briand-Suleau A; Vidaud D; Ortonne N; Pasmant E; Upadhyaya M
    Genes Chromosomes Cancer; 2017 May; 56(5):421-426. PubMed ID: 28124441
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice.
    Song CQ; Li Y; Mou H; Moore J; Park A; Pomyen Y; Hough S; Kennedy Z; Fischer A; Yin H; Anderson DG; Conte D; Zender L; Wang XW; Thorgeirsson S; Weng Z; Xue W
    Gastroenterology; 2017 Apr; 152(5):1161-1173.e1. PubMed ID: 27956228
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms.
    Longo JF; Brosius SN; Black L; Worley SH; Wilson RC; Roth KA; Carroll SL
    Cell Commun Signal; 2019 Jul; 17(1):74. PubMed ID: 31291965
    [TBL] [Abstract][Full Text] [Related]  

  • 14.
    Oppel F; Ki DH; Zimmerman MW; Ross KN; Tao T; Shi H; He S; Aster JC; Look AT
    Dis Model Mech; 2020 Aug; 13(8):. PubMed ID: 32651197
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A neurogenic tumor containing a low-grade malignant peripheral nerve sheath tumor (MPNST) component with loss of p16 expression and homozygous deletion of CDKN2A/p16: a case report showing progression from a neurofibroma to a high-grade MPNST.
    Tajima S; Koda K
    Int J Clin Exp Pathol; 2015; 8(5):5113-20. PubMed ID: 26191206
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.
    Park HJ; Lee SJ; Sohn YB; Jin HS; Han JH; Kim YB; Yim H; Jeong SY
    Int J Oncol; 2013 Feb; 42(2):657-66. PubMed ID: 23292448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Malignant peripheral nerve sheath tumor (MPNST) and MPNST-like entities are defined by a specific DNA methylation profile in pediatric and juvenile population.
    Patrizi S; Miele E; Falcone L; Vallese S; Rossi S; Barresi S; Giovannoni I; Pedace L; Nardini C; Masier I; Abballe L; Cacchione A; Russo I; Di Giannatale A; Di Ruscio V; Salgado CM; Mastronuzzi A; Ciolfi A; Tartaglia M; Milano GM; Locatelli F; Alaggio R
    Clin Epigenetics; 2024 Jan; 16(1):9. PubMed ID: 38178234
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo.
    Maharjan CK; Umesalma S; Kaemmer CA; Muniz VP; Bauchle C; Mott SL; Zamba KD; Breheny P; Leidinger MR; Darbro BW; Stephens SB; Meyerholz DK; Quelle DE
    Biomedicines; 2021 Jun; 9(6):. PubMed ID: 34199469
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Clinical genomic profiling identifies TYK2 mutation and overexpression in patients with neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.
    Hirbe AC; Kaushal M; Sharma MK; Dahiya S; Pekmezci M; Perry A; Gutmann DH
    Cancer; 2017 Apr; 123(7):1194-1201. PubMed ID: 27875628
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST.
    Lu HC; Eulo V; Apicelli AJ; Pekmezci M; Tao Y; Luo J; Hirbe AC; Dahiya S
    Oncotarget; 2018 May; 9(33):23018-23028. PubMed ID: 29796169
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.