214 related articles for article (PubMed ID: 35587487)
1. Pilot study evaluating everolimus molecular mechanisms in tuberous sclerosis complex and focal cortical dysplasia.
Leitner DF; Kanshin E; Askenazi M; Siu Y; Friedman D; Devore S; Jones D; Ueberheide B; Wisniewski T; Devinsky O
PLoS One; 2022; 17(5):e0268597. PubMed ID: 35587487
[TBL] [Abstract][Full Text] [Related]
2. mTOR Hyperactivity Levels Influence the Severity of Epilepsy and Associated Neuropathology in an Experimental Model of Tuberous Sclerosis Complex and Focal Cortical Dysplasia.
Nguyen LH; Mahadeo T; Bordey A
J Neurosci; 2019 Apr; 39(14):2762-2773. PubMed ID: 30700531
[TBL] [Abstract][Full Text] [Related]
3. mTOR pathway activation in focal cortical dysplasia.
Kumari K; Sharma MC; Kakkar A; Malgulwar PB; Pathak P; Suri V; Sarkar C; Chandra SP; Faruq M
Ann Diagn Pathol; 2020 Jun; 46():151523. PubMed ID: 32325422
[TBL] [Abstract][Full Text] [Related]
4. Efficacy and safety of Everolimus in children with TSC - associated epilepsy - Pilot data from an open single-center prospective study.
Samueli S; Abraham K; Dressler A; Gröppel G; Mühlebner-Fahrngruber A; Scholl T; Kasprian G; Laccone F; Feucht M
Orphanet J Rare Dis; 2016 Nov; 11(1):145. PubMed ID: 27809914
[TBL] [Abstract][Full Text] [Related]
5. Activation of extracellular regulated kinase and mechanistic target of rapamycin pathway in focal cortical dysplasia.
Patil VV; Guzman M; Carter AN; Rathore G; Yoshor D; Curry D; Wilfong A; Agadi S; Swann JW; Adesina AM; Bhattacharjee MB; Anderson AE
Neuropathology; 2016 Apr; 36(2):146-56. PubMed ID: 26381727
[TBL] [Abstract][Full Text] [Related]
6. Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age - a multicenter retrospective study.
Saffari A; Brösse I; Wiemer-Kruel A; Wilken B; Kreuzaler P; Hahn A; Bernhard MK; van Tilburg CM; Hoffmann GF; Gorenflo M; Hethey S; Kaiser O; Kölker S; Wagner R; Witt O; Merkenschlager A; Möckel A; Roser T; Schlump JU; Serfling A; Spiegler J; Milde T; Ziegler A; Syrbe S
Orphanet J Rare Dis; 2019 May; 14(1):96. PubMed ID: 31053163
[TBL] [Abstract][Full Text] [Related]
7. Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies.
Liu J; Reeves C; Michalak Z; Coppola A; Diehl B; Sisodiya SM; Thom M
Acta Neuropathol Commun; 2014 Jul; 2():71. PubMed ID: 25005575
[TBL] [Abstract][Full Text] [Related]
8. Insulin signaling pathways in cortical dysplasia and TSC-tubers: tissue microarray analysis.
Miyata H; Chiang AC; Vinters HV
Ann Neurol; 2004 Oct; 56(4):510-9. PubMed ID: 15455398
[TBL] [Abstract][Full Text] [Related]
9. Impaired oligodendroglial turnover is associated with myelin pathology in focal cortical dysplasia and tuberous sclerosis complex.
Scholl T; Mühlebner A; Ricken G; Gruber V; Fabing A; Samueli S; Gröppel G; Dorfer C; Czech T; Hainfellner JA; Prabowo AS; Reinten RJ; Hoogendijk L; Anink JJ; Aronica E; Feucht M
Brain Pathol; 2017 Nov; 27(6):770-780. PubMed ID: 27750396
[TBL] [Abstract][Full Text] [Related]
10. mTOR cascade activation distinguishes tubers from focal cortical dysplasia.
Baybis M; Yu J; Lee A; Golden JA; Weiner H; McKhann G; Aronica E; Crino PB
Ann Neurol; 2004 Oct; 56(4):478-87. PubMed ID: 15455405
[TBL] [Abstract][Full Text] [Related]
11. Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study.
French JA; Lawson JA; Yapici Z; Ikeda H; Polster T; Nabbout R; Curatolo P; de Vries PJ; Dlugos DJ; Berkowitz N; Voi M; Peyrard S; Pelov D; Franz DN
Lancet; 2016 Oct; 388(10056):2153-2163. PubMed ID: 27613521
[TBL] [Abstract][Full Text] [Related]
12. Mechanistic target of rapamycin (mTOR) in tuberous sclerosis complex-associated epilepsy.
Curatolo P
Pediatr Neurol; 2015 Mar; 52(3):281-9. PubMed ID: 25591831
[TBL] [Abstract][Full Text] [Related]
13. [The Efficacy of Everolimus for Refractory Seizures in Childhood Onset Epilepsy with Tuberous Sclerosis Complex].
Okanishi T; Fujimoto A; Nishimura M; Baba S; Itamura S; Okanari K; Enoki H
Brain Nerve; 2019 Jun; 71(6):611-616. PubMed ID: 31171758
[TBL] [Abstract][Full Text] [Related]
14. mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis.
Yasin SA; Ali AM; Tata M; Picker SR; Anderson GW; Latimer-Bowman E; Nicholson SL; Harkness W; Cross JH; Paine SM; Jacques TS
Acta Neuropathol; 2013 Aug; 126(2):207-18. PubMed ID: 23728790
[TBL] [Abstract][Full Text] [Related]
15. Long-term effect of everolimus on epilepsy and growth in children under 3 years of age treated for subependymal giant cell astrocytoma associated with tuberous sclerosis complex.
Kotulska K; Chmielewski D; Borkowska J; Jurkiewicz E; Kuczyński D; Kmieć T; Łojszczyk B; Dunin-Wąsowicz D; Jóźwiak S
Eur J Paediatr Neurol; 2013 Sep; 17(5):479-85. PubMed ID: 23567018
[TBL] [Abstract][Full Text] [Related]
16. Genetic pathogenesis of the epileptogenic lesions in Tuberous Sclerosis Complex: Therapeutic targeting of the mTOR pathway.
Moavero R; Mühlebner A; Luinenburg MJ; Craiu D; Aronica E; Curatolo P
Epilepsy Behav; 2022 Jun; 131(Pt B):107713. PubMed ID: 33431351
[TBL] [Abstract][Full Text] [Related]
17. Mammalian target of rapamycin (mTOR) activation in focal cortical dysplasia and related focal cortical malformations.
Wong M
Exp Neurol; 2013 Jun; 244():22-6. PubMed ID: 22015915
[TBL] [Abstract][Full Text] [Related]
18. mTOR-therapy and targeted treatment opportunities in mTOR-related epilepsies associated with cortical malformations.
Auvin S; Baulac S
Rev Neurol (Paris); 2023 Apr; 179(4):337-344. PubMed ID: 36906459
[TBL] [Abstract][Full Text] [Related]
19. Everolimus as adjunctive therapy for tuberous sclerosis complex-associated partial-onset seizures.
Lechuga L; Franz DN
Expert Rev Neurother; 2019 Oct; 19(10):913-925. PubMed ID: 31335226
[No Abstract] [Full Text] [Related]
20. Differentiating the mTOR inhibitors everolimus and sirolimus in the treatment of tuberous sclerosis complex.
MacKeigan JP; Krueger DA
Neuro Oncol; 2015 Dec; 17(12):1550-9. PubMed ID: 26289591
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
