These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 35595932)

  • 1. Selective Signal Capture from Multidimensional GPCR Outputs with Biased Agonists: Progress Towards Novel Drug Development.
    Kim D; Tokmakova A; Woo JA; An SS; Goddard WA; Liggett SB
    Mol Diagn Ther; 2022 Jul; 26(4):383-396. PubMed ID: 35595932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
    Luttrell LM; Maudsley S; Bohn LM
    Mol Pharmacol; 2015 Sep; 88(3):579-88. PubMed ID: 26134495
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy.
    Rahmeh R; Damian M; Cottet M; Orcel H; Mendre C; Durroux T; Sharma KS; Durand G; Pucci B; Trinquet E; Zwier JM; Deupi X; Bron P; Banères JL; Mouillac B; Granier S
    Proc Natl Acad Sci U S A; 2012 Apr; 109(17):6733-8. PubMed ID: 22493271
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biased signaling of G protein coupled receptors (GPCRs): Molecular determinants of GPCR/transducer selectivity and therapeutic potential.
    Seyedabadi M; Ghahremani MH; Albert PR
    Pharmacol Ther; 2019 Aug; 200():148-178. PubMed ID: 31075355
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors.
    Nivedha AK; Tautermann CS; Bhattacharya S; Lee S; Casarosa P; Kollak I; Kiechle T; Vaidehi N
    Mol Pharmacol; 2018 Apr; 93(4):288-296. PubMed ID: 29367258
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.
    Shonberg J; Lopez L; Scammells PJ; Christopoulos A; Capuano B; Lane JR
    Med Res Rev; 2014 Nov; 34(6):1286-330. PubMed ID: 24796277
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Class B1 GPCR activation by an intracellular agonist.
    Kobayashi K; Kawakami K; Kusakizako T; Tomita A; Nishimura M; Sawada K; Okamoto HH; Hiratsuka S; Nakamura G; Kuwabara R; Noda H; Muramatsu H; Shimizu M; Taguchi T; Inoue A; Murata T; Nureki O
    Nature; 2023 Jun; 618(7967):1085-1093. PubMed ID: 37286611
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Simulations of biased agonists in the β(2) adrenergic receptor with accelerated molecular dynamics.
    Tikhonova IG; Selvam B; Ivetac A; Wereszczynski J; McCammon JA
    Biochemistry; 2013 Aug; 52(33):5593-603. PubMed ID: 23879802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biased receptor functionality versus biased agonism in G-protein-coupled receptors.
    Franco R; Aguinaga D; Jiménez J; Lillo J; Martínez-Pinilla E; Navarro G
    Biomol Concepts; 2018 Dec; 9(1):143-154. PubMed ID: 30864350
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of functional selectivity through G protein-dependent and -independent signaling pathways at the adrenergic α(2C) receptor.
    Kurko D; Kapui Z; Nagy J; Lendvai B; Kolok S
    Brain Res Bull; 2014 Aug; 107():89-101. PubMed ID: 25080296
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric coupling and biased agonism in G protein-coupled receptors.
    Bock A; Bermudez M
    FEBS J; 2021 Apr; 288(8):2513-2528. PubMed ID: 33621418
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Emerging structural insights into biased GPCR signaling.
    Shukla AK; Singh G; Ghosh E
    Trends Biochem Sci; 2014 Dec; 39(12):594-602. PubMed ID: 25458114
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serodolin, a β-arrestin-biased ligand of 5-HT
    El Khamlichi C; Reverchon F; Hervouet-Coste N; Robin E; Chopin N; Deau E; Madouri F; Guimpied C; Colas C; Menuet A; Inoue A; Bojarski AJ; Guillaumet G; Suzenet F; Reiter E; Morisset-Lopez S
    Proc Natl Acad Sci U S A; 2022 May; 119(21):e2118847119. PubMed ID: 35594393
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors.
    Southern C; Cook JM; Neetoo-Isseljee Z; Taylor DL; Kettleborough CA; Merritt A; Bassoni DL; Raab WJ; Quinn E; Wehrman TS; Davenport AP; Brown AJ; Green A; Wigglesworth MJ; Rees S
    J Biomol Screen; 2013 Jun; 18(5):599-609. PubMed ID: 23396314
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Beta-arrestin biased agonism/antagonism at cardiovascular seven transmembrane-spanning receptors.
    Lymperopoulos A
    Curr Pharm Des; 2012; 18(2):192-8. PubMed ID: 22229558
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential.
    Tan L; Yan W; McCorvy JD; Cheng J
    J Med Chem; 2018 Nov; 61(22):9841-9878. PubMed ID: 29939744
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity.
    Sanchez-Soto M; Verma RK; Willette BKA; Gonye EC; Moore AM; Moritz AE; Boateng CA; Yano H; Free RB; Shi L; Sibley DR
    Sci Signal; 2020 Feb; 13(617):. PubMed ID: 32019899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biased β-Agonists Favoring Gs over β-Arrestin for Individualized Treatment of Obstructive Lung Disease.
    Tokmakova A; Kim D; Goddard WA; Liggett SB
    J Pers Med; 2022 Feb; 12(3):. PubMed ID: 35330331
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conserved class B GPCR activation by a biased intracellular agonist.
    Zhao LH; He Q; Yuan Q; Gu Y; He X; Shan H; Li J; Wang K; Li Y; Hu W; Wu K; Shen J; Xu HE
    Nature; 2023 Sep; 621(7979):635-641. PubMed ID: 37524305
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors.
    Reiter E; Ahn S; Shukla AK; Lefkowitz RJ
    Annu Rev Pharmacol Toxicol; 2012; 52():179-97. PubMed ID: 21942629
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.