These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 35613602)

  • 1. Spatiotemporal feedforward between PKM2 tetramers and mTORC1 prompts mTORC1 activation.
    Xia Y; Wang S; Song C; Luo RY
    Phys Biol; 2022 Jun; 19(4):. PubMed ID: 35613602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.
    Ye J; Mancuso A; Tong X; Ward PS; Fan J; Rabinowitz JD; Thompson CB
    Proc Natl Acad Sci U S A; 2012 May; 109(18):6904-9. PubMed ID: 22509023
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pyruvate kinase: Function, regulation and role in cancer.
    Israelsen WJ; Vander Heiden MG
    Semin Cell Dev Biol; 2015 Jul; 43():43-51. PubMed ID: 26277545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of PKM2 in directing the metabolic fate of glucose in cancer: a potential therapeutic target.
    van Niekerk G; Engelbrecht AM
    Cell Oncol (Dordr); 2018 Aug; 41(4):343-351. PubMed ID: 29797241
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple functions of pyruvate kinase M2 in various cell types.
    Lee YB; Min JK; Kim JG; Cap KC; Islam R; Hossain AJ; Dogsom O; Hamza A; Mahmud S; Choi DR; Kim YS; Koh YH; Kim HA; Chung WS; Suh SW; Park JB
    J Cell Physiol; 2022 Jan; 237(1):128-148. PubMed ID: 34311499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
    Sun Q; Chen X; Ma J; Peng H; Wang F; Zha X; Wang Y; Jing Y; Yang H; Chen R; Chang L; Zhang Y; Goto J; Onda H; Chen T; Wang MR; Lu Y; You H; Kwiatkowski D; Zhang H
    Proc Natl Acad Sci U S A; 2011 Mar; 108(10):4129-34. PubMed ID: 21325052
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
    Lee MN; Ha SH; Kim J; Koh A; Lee CS; Kim JH; Jeon H; Kim DH; Suh PG; Ryu SH
    Mol Cell Biol; 2009 Jul; 29(14):3991-4001. PubMed ID: 19451232
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.
    Kim SG; Hoffman GR; Poulogiannis G; Buel GR; Jang YJ; Lee KW; Kim BY; Erikson RL; Cantley LC; Choo AY; Blenis J
    Mol Cell; 2013 Jan; 49(1):172-85. PubMed ID: 23142078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin.
    Iqbal MA; Bamezai RN
    PLoS One; 2012; 7(5):e36764. PubMed ID: 22574221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase.
    Mor I; Carlessi R; Ast T; Feinstein E; Kimchi A
    Oncogene; 2012 Feb; 31(6):683-93. PubMed ID: 21725354
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1).
    Shibutani S; Okazaki H; Iwata H
    J Biol Chem; 2017 Nov; 292(44):18052-18061. PubMed ID: 28808055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aberrant overexpression of pyruvate kinase M2 is associated with aggressive tumor features and the BRAF mutation in papillary thyroid cancer.
    Feng C; Gao Y; Wang C; Yu X; Zhang W; Guan H; Shan Z; Teng W
    J Clin Endocrinol Metab; 2013 Sep; 98(9):E1524-33. PubMed ID: 23846818
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop.
    Luan W; Wang Y; Chen X; Shi Y; Wang J; Zhang J; Qian J; Li R; Tao T; Wei W; Hu Q; Liu N; You Y
    Oncotarget; 2015 May; 6(15):13006-18. PubMed ID: 25948776
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spatial regulation of mTORC1 signalling: Beyond the Rag GTPases.
    Carroll B
    Semin Cell Dev Biol; 2020 Nov; 107():103-111. PubMed ID: 32122730
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
    Liu Z; Chen X; Wang Y; Peng H; Wang Y; Jing Y; Zhang H
    J Biol Chem; 2014 Oct; 289(43):29739-49. PubMed ID: 25164809
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
    Iqbal MA; Siddiqui FA; Gupta V; Chattopadhyay S; Gopinath P; Kumar B; Manvati S; Chaman N; Bamezai RN
    Mol Cancer; 2013 Jul; 12():72. PubMed ID: 23837608
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
    Hitosugi T; Kang S; Vander Heiden MG; Chung TW; Elf S; Lythgoe K; Dong S; Lonial S; Wang X; Chen GZ; Xie J; Gu TL; Polakiewicz RD; Roesel JL; Boggon TJ; Khuri FR; Gilliland DG; Cantley LC; Kaufman J; Chen J
    Sci Signal; 2009 Nov; 2(97):ra73. PubMed ID: 19920251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PKM2-dependent metabolic reprogramming in CD4
    Lü S; Deng J; Liu H; Liu B; Yang J; Miao Y; Li J; Wang N; Jiang C; Xu Q; Wang X; Feng J
    J Mol Med (Berl); 2018 Jun; 96(6):585-600. PubMed ID: 29732501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
    Chiavarina B; Whitaker-Menezes D; Martinez-Outschoorn UE; Witkiewicz AK; Birbe R; Howell A; Pestell RG; Smith J; Daniel R; Sotgia F; Lisanti MP
    Cancer Biol Ther; 2011 Dec; 12(12):1101-13. PubMed ID: 22236875
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancing 5-fluorouracil efficacy through suppression of PKM2 in colorectal cancer cells.
    Cao Y; Lin Y; Wang D; Pan D; Zhang Y; Jin Y; Zheng C
    Cancer Chemother Pharmacol; 2018 Dec; 82(6):1081-1086. PubMed ID: 30155759
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.