167 related articles for article (PubMed ID: 35617047)
1. RRM1 variants cause a mitochondrial DNA maintenance disorder via impaired de novo nucleotide synthesis.
Shintaku J; Pernice WM; Eyaid W; Gc JB; Brown ZP; Juanola-Falgarona M; Torres-Torronteras J; Sommerville EW; Hellebrekers DM; Blakely EL; Donaldson A; van de Laar I; Leu CS; Marti R; Frank J; Tanji K; Koolen DA; Rodenburg RJ; Chinnery PF; Smeets HJM; Gorman GS; Bonnen PE; Taylor RW; Hirano M
J Clin Invest; 2022 Jul; 132(13):. PubMed ID: 35617047
[TBL] [Abstract][Full Text] [Related]
2. Deoxyribonucleotide metabolism in cycling and resting human fibroblasts with a missense mutation in p53R2, a subunit of ribonucleotide reductase.
Pontarin G; Ferraro P; Rampazzo C; Kollberg G; Holme E; Reichard P; Bianchi V
J Biol Chem; 2011 Apr; 286(13):11132-40. PubMed ID: 21297166
[TBL] [Abstract][Full Text] [Related]
3. Ribonucleotide reductase subunit p53R2 regulates mitochondria homeostasis and function in KB and PC-3 cancer cells.
Wang X; Liu X; Xue L; Zhang K; Kuo ML; Hu S; Zhou B; Ann D; Zhang S; Yen Y
Biochem Biophys Res Commun; 2011 Jun; 410(1):102-7. PubMed ID: 21640705
[TBL] [Abstract][Full Text] [Related]
4. Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells.
Pontarin G; Ferraro P; Bee L; Reichard P; Bianchi V
Proc Natl Acad Sci U S A; 2012 Aug; 109(33):13302-7. PubMed ID: 22847445
[TBL] [Abstract][Full Text] [Related]
5. Ribonucleotide reductase is not limiting for mitochondrial DNA copy number in mice.
Ylikallio E; Page JL; Xu X; Lampinen M; Bepler G; Ide T; Tyynismaa H; Weiss RS; Suomalainen A
Nucleic Acids Res; 2010 Dec; 38(22):8208-18. PubMed ID: 20724444
[TBL] [Abstract][Full Text] [Related]
6. Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Bourdon A; Minai L; Serre V; Jais JP; Sarzi E; Aubert S; Chrétien D; de Lonlay P; Paquis-Flucklinger V; Arakawa H; Nakamura Y; Munnich A; Rötig A
Nat Genet; 2007 Jun; 39(6):776-80. PubMed ID: 17486094
[TBL] [Abstract][Full Text] [Related]
7. Mitochondrial purine and pyrimidine metabolism and beyond.
Wang L
Nucleosides Nucleotides Nucleic Acids; 2016 Dec; 35(10-12):578-594. PubMed ID: 27906631
[TBL] [Abstract][Full Text] [Related]
8. Depletion of the other genome-mitochondrial DNA depletion syndromes in humans.
Elpeleg O; Mandel H; Saada A
J Mol Med (Berl); 2002 Jul; 80(7):389-96. PubMed ID: 12110944
[TBL] [Abstract][Full Text] [Related]
9. Defects in mitochondrial DNA replication and human disease.
Copeland WC
Crit Rev Biochem Mol Biol; 2012; 47(1):64-74. PubMed ID: 22176657
[TBL] [Abstract][Full Text] [Related]
10. A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development.
Specks J; Lecona E; Lopez-Contreras AJ; Fernandez-Capetillo O
Mol Cell Biol; 2015 Sep; 35(17):2910-7. PubMed ID: 26077802
[TBL] [Abstract][Full Text] [Related]
11. Basic biochemical characterization of cytosolic enzymes in thymidine nucleotide synthesis in adult rat tissues: implications for tissue specific mitochondrial DNA depletion and deoxynucleoside-based therapy for TK2-deficiency.
Wang L; Sun R; Eriksson S
BMC Mol Cell Biol; 2020 Apr; 21(1):33. PubMed ID: 32345222
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of mitochondrial DNA precursors during myogenesis, an analysis in purified C2C12 myotubes.
Frangini M; Franzolin E; Chemello F; Laveder P; Romualdi C; Bianchi V; Rampazzo C
J Biol Chem; 2013 Feb; 288(8):5624-35. PubMed ID: 23297407
[TBL] [Abstract][Full Text] [Related]
13. Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication.
Foskolou IP; Jorgensen C; Leszczynska KB; Olcina MM; Tarhonskaya H; Haisma B; D'Angiolella V; Myers WK; Domene C; Flashman E; Hammond EM
Mol Cell; 2017 Apr; 66(2):206-220.e9. PubMed ID: 28416140
[TBL] [Abstract][Full Text] [Related]
14. Increased dNTP pools rescue mtDNA depletion in human POLG-deficient fibroblasts.
Blázquez-Bermejo C; Carreño-Gago L; Molina-Granada D; Aguirre J; Ramón J; Torres-Torronteras J; Cabrera-Pérez R; Martín MÁ; Domínguez-González C; de la Cruz X; Lombès A; García-Arumí E; Martí R; Cámara Y
FASEB J; 2019 Jun; 33(6):7168-7179. PubMed ID: 30848931
[TBL] [Abstract][Full Text] [Related]
15. The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.
Zhou B; Liu X; Mo X; Xue L; Darwish D; Qiu W; Shih J; Hwu EB; Luh F; Yen Y
Cancer Res; 2003 Oct; 63(20):6583-94. PubMed ID: 14583450
[TBL] [Abstract][Full Text] [Related]
16. Deoxynucleoside salvage enzymes and tissue specific mitochondrial DNA depletion.
Wang L
Nucleosides Nucleotides Nucleic Acids; 2010 Jun; 29(4-6):370-81. PubMed ID: 20544522
[TBL] [Abstract][Full Text] [Related]
17. Identification of a novel heterozygous guanosine monophosphate reductase (GMPR) variant in a patient with a late-onset disorder of mitochondrial DNA maintenance.
Sommerville EW; Dalla Rosa I; Rosenberg MM; Bruni F; Thompson K; Rocha M; Blakely EL; He L; Falkous G; Schaefer AM; Yu-Wai-Man P; Chinnery PF; Hedstrom L; Spinazzola A; Taylor RW; Gorman GS
Clin Genet; 2020 Feb; 97(2):276-286. PubMed ID: 31600844
[TBL] [Abstract][Full Text] [Related]
18. Cell-cycle-dependent phosphorylation of RRM1 ensures efficient DNA replication and regulates cancer vulnerability to ATR inhibition.
Shu Z; Li Z; Huang H; Chen Y; Fan J; Yu L; Wu Z; Tian L; Qi Q; Peng S; Wei C; Xie Z; Li X; Feng Q; Sheng H; Li G; Wei D; Shan C; Chen G
Oncogene; 2020 Aug; 39(35):5721-5733. PubMed ID: 32712628
[TBL] [Abstract][Full Text] [Related]
19. Identification of two novel RRM2B variants associated with autosomal recessive progressive external ophthalmoplegia in a family with pseudodominant inheritance pattern.
Restrepo-Vera JL; Rovira-Moreno E; Ramón J; Codina-Sola M; Llauradó A; Salvadó M; Sánchez-Tejerina D; Sotoca J; Martínez-Sáez E; Martí R; García-Arumí E; Juntas-Morales R
J Hum Genet; 2023 Aug; 68(8):527-532. PubMed ID: 36959467
[TBL] [Abstract][Full Text] [Related]
20. A heterozygous truncating mutation in RRM2B causes autosomal-dominant progressive external ophthalmoplegia with multiple mtDNA deletions.
Tyynismaa H; Ylikallio E; Patel M; Molnar MJ; Haller RG; Suomalainen A
Am J Hum Genet; 2009 Aug; 85(2):290-5. PubMed ID: 19664747
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
