BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 35618489)

  • 1. 3D-QSAR and scaffold hopping based designing of benzo[d]ox-azol-2(3H)-one and 2-oxazolo[4,5-b]pyridin-2(3H)-one derivatives as selective aldehyde dehydrogenase 1A1 inhibitors: Synthesis and biological evaluation.
    Verma H; Narendra G; Raju B; Kumar M; Jain SK; Tung GK; Singh PK; Silakari O
    Arch Pharm (Weinheim); 2022 Sep; 355(9):e2200108. PubMed ID: 35618489
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Scaffold hopping based designing of selective ALDH1A1 inhibitors to overcome cyclophosphamide resistance: synthesis and biological evaluation.
    Narendra G; Raju B; Verma H; Kumar M; Jain SK; Tung GK; Thakur S; Kaur R; Kaur S; Sapra B; Silakari O
    RSC Med Chem; 2024 Jan; 15(1):309-321. PubMed ID: 38283216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of benzimidazole derivatives as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity.
    Ma Z; Jiang L; Li B; Liang D; Feng Y; Liu L; Jiang C
    Bioorg Med Chem; 2021 Sep; 46():116352. PubMed ID: 34403955
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Raloxifene and bazedoxifene as selective ALDH1A1 inhibitors to ameliorate cyclophosphamide resistance: A drug repurposing approach.
    Narendra G; Raju B; Verma H; Kumar M; Jain SK; Tung GK; Thakur S; Kaur R; Kaur S; Sapra B; Singh PK; Silakari O
    Int J Biol Macromol; 2023 Jul; 242(Pt 1):124749. PubMed ID: 37160174
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives.
    Buchman CD; Hurley TD
    J Med Chem; 2017 Mar; 60(6):2439-2455. PubMed ID: 28219011
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel Disulfiram Derivatives as ALDH1a1-Selective Inhibitors.
    Omran Z
    Molecules; 2022 Jan; 27(2):. PubMed ID: 35056791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity.
    Ma Z; Jiang L; Li G; Liang D; Li L; Liu L; Jiang C
    Bioorg Chem; 2020 Aug; 101():103971. PubMed ID: 32480173
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.
    Parajuli B; Georgiadis TM; Fishel ML; Hurley TD
    Chembiochem; 2014 Mar; 15(5):701-12. PubMed ID: 24677340
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.
    Koch MF; Harteis S; Blank ID; Pestel G; Tietze LF; Ochsenfeld C; Schneider S; Sieber SA
    Angew Chem Int Ed Engl; 2015 Nov; 54(46):13550-4. PubMed ID: 26373694
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of coumarin-based selective aldehyde dehydrogenase 1A1 inhibitors with glucose metabolism improving activity.
    Liang D; Fan Y; Yang Z; Zhang Z; Liu M; Liu L; Jiang C
    Eur J Med Chem; 2020 Feb; 187():111923. PubMed ID: 31816557
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multiple machine learning models combined with virtual screening and molecular docking to identify selective human ALDH1A1 inhibitors.
    Narendra G; Raju B; Verma H; Sapra B; Silakari O
    J Mol Graph Model; 2021 Sep; 107():107950. PubMed ID: 34089986
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).
    Yang SM; Yasgar A; Miller B; Lal-Nag M; Brimacombe K; Hu X; Sun H; Wang A; Xu X; Nguyen K; Oppermann U; Ferrer M; Vasiliou V; Simeonov A; Jadhav A; Maloney DJ
    J Med Chem; 2015 Aug; 58(15):5967-78. PubMed ID: 26207746
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biological evaluation and 3D-QSAR studies of curcumin analogues as aldehyde dehydrogenase 1 inhibitors.
    Wang H; Du Z; Zhang C; Tang Z; He Y; Zhang Q; Zhao J; Zheng X
    Int J Mol Sci; 2014 May; 15(5):8795-807. PubMed ID: 24840575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
    Morgan CA; Hurley TD
    Chem Biol Interact; 2015 Jun; 234():29-37. PubMed ID: 25450233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery and development of selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors.
    Li B; Yang K; Liang D; Jiang C; Ma Z
    Eur J Med Chem; 2021 Jan; 209():112940. PubMed ID: 33328099
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of
    Nowacka M; Ginter-Matuszewska B; Świerczewska M; Sterzyńska K; Nowicki M; Januchowski R
    Int J Mol Sci; 2022 Mar; 23(6):. PubMed ID: 35328460
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Investigating the Role of Missense SNPs on ALDH 1A1 mediated pharmacokinetic resistance to cyclophosphamide.
    Verma H; Silakari O
    Comput Biol Med; 2020 Oct; 125():103979. PubMed ID: 32877739
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
    Jiménez R; Pequerul R; Amor A; Lorenzo J; Metwally K; Avilés FX; Parés X; Farrés J
    Chem Biol Interact; 2019 Jun; 306():123-130. PubMed ID: 30958995
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insight into the Structural Requirements of Theophylline-Based Aldehyde Dehydrogenase lAl (ALDHlAl) Inhibitors Through Multi-QSAR Modeling and Molecular Docking Approaches.
    Abdul Amin S; Adhikari N; Gayen S; Jha T
    Curr Drug Discov Technol; 2016; 13(2):84-100. PubMed ID: 27132720
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Murine hepatic aldehyde dehydrogenase 1a1 is a major contributor to oxidation of aldehydes formed by lipid peroxidation.
    Makia NL; Bojang P; Falkner KC; Conklin DJ; Prough RA
    Chem Biol Interact; 2011 May; 191(1-3):278-87. PubMed ID: 21256123
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.