228 related articles for article (PubMed ID: 35618846)
1. Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells.
Qin K; Huang P; Feng R; Keller CA; Peslak SA; Khandros E; Saari MS; Lan X; Mayuranathan T; Doerfler PA; Abdulmalik O; Giardine B; Chou ST; Shi J; Hardison RC; Weiss MJ; Blobel GA
Nat Genet; 2022 Jun; 54(6):874-884. PubMed ID: 35618846
[TBL] [Abstract][Full Text] [Related]
2. Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.
McConnell SC; Huo Y; Liu S; Ryan TM
Mol Cell Biol; 2011 Feb; 31(4):876-83. PubMed ID: 21173165
[TBL] [Abstract][Full Text] [Related]
3. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
Traxler EA; Yao Y; Wang YD; Woodard KJ; Kurita R; Nakamura Y; Hughes JR; Hardison RC; Blobel GA; Li C; Weiss MJ
Nat Med; 2016 Sep; 22(9):987-90. PubMed ID: 27525524
[TBL] [Abstract][Full Text] [Related]
4. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
[TBL] [Abstract][Full Text] [Related]
5. Identification of novel γ-globin inducers among all potential erythroid druggable targets.
Yu L; Myers G; Schneider E; Wang Y; Mathews R; Lim KC; Siemieniak D; Tang V; Ginsburg D; Balbin-Cuesta G; Singh SA; Phuwakanjana P; Jearawiriyapaisarn N; Khoriaty R; Engel JD
Blood Adv; 2022 Jun; 6(11):3280-3285. PubMed ID: 35240686
[TBL] [Abstract][Full Text] [Related]
6. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M
Nat Genet; 2018 Apr; 50(4):498-503. PubMed ID: 29610478
[TBL] [Abstract][Full Text] [Related]
7. Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells.
Amaya M; Desai M; Gnanapragasam MN; Wang SZ; Zu Zhu S; Williams DC; Ginder GD
Blood; 2013 Apr; 121(17):3493-501. PubMed ID: 23444401
[TBL] [Abstract][Full Text] [Related]
8. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
[TBL] [Abstract][Full Text] [Related]
9. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
[TBL] [Abstract][Full Text] [Related]
10. Genome editing of HBG1 and HBG2 to induce fetal hemoglobin.
Métais JY; Doerfler PA; Mayuranathan T; Bauer DE; Fowler SC; Hsieh MM; Katta V; Keriwala S; Lazzarotto CR; Luk K; Neel MD; Perry SS; Peters ST; Porter SN; Ryu BY; Sharma A; Shea D; Tisdale JF; Uchida N; Wolfe SA; Woodard KJ; Wu Y; Yao Y; Zeng J; Pruett-Miller S; Tsai SQ; Weiss MJ
Blood Adv; 2019 Nov; 3(21):3379-3392. PubMed ID: 31698466
[TBL] [Abstract][Full Text] [Related]
11. Epigenetic regulation of fetal globin gene expression in adult erythroid cells.
Ginder GD
Transl Res; 2015 Jan; 165(1):115-25. PubMed ID: 24880147
[TBL] [Abstract][Full Text] [Related]
12. Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.
Trakarnsanga K; Wilson MC; Lau W; Singleton BK; Parsons SF; Sakuntanaga P; Kurita R; Nakamura Y; Anstee DJ; Frayne J
Haematologica; 2014 Nov; 99(11):1677-85. PubMed ID: 25107887
[TBL] [Abstract][Full Text] [Related]
13. PUM1 mediates the posttranscriptional regulation of human fetal hemoglobin.
Elagooz R; Dhara AR; Gott RM; Adams SE; White RA; Ghosh A; Ganguly S; Man Y; Owusu-Ansah A; Mian OY; Gurkan UA; Komar AA; Ramamoorthy M; Gnanapragasam MN
Blood Adv; 2022 Dec; 6(23):6016-6022. PubMed ID: 35667093
[TBL] [Abstract][Full Text] [Related]
14. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
15. Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations.
Woodard KJ; Doerfler PA; Mayberry KD; Sharma A; Levine R; Yen J; Valentine V; Palmer LE; Valentine M; Weiss MJ
Dis Model Mech; 2022 Jun; 15(6):. PubMed ID: 35793591
[TBL] [Abstract][Full Text] [Related]
16. HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.
Huang P; Peslak SA; Ren R; Khandros E; Qin K; Keller CA; Giardine B; Bell HW; Lan X; Sharma M; Horton JR; Abdulmalik O; Chou ST; Shi J; Crossley M; Hardison RC; Cheng X; Blobel GA
Nat Genet; 2022 Sep; 54(9):1417-1426. PubMed ID: 35941187
[TBL] [Abstract][Full Text] [Related]
17. Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
Liu N; Xu S; Yao Q; Zhu Q; Kai Y; Hsu JY; Sakon P; Pinello L; Yuan GC; Bauer DE; Orkin SH
Nat Genet; 2021 Apr; 53(4):511-520. PubMed ID: 33649594
[TBL] [Abstract][Full Text] [Related]
18. Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Wu Y; Zeng J; Roscoe BP; Liu P; Yao Q; Lazzarotto CR; Clement K; Cole MA; Luk K; Baricordi C; Shen AH; Ren C; Esrick EB; Manis JP; Dorfman DM; Williams DA; Biffi A; Brugnara C; Biasco L; Brendel C; Pinello L; Tsai SQ; Wolfe SA; Bauer DE
Nat Med; 2019 May; 25(5):776-783. PubMed ID: 30911135
[TBL] [Abstract][Full Text] [Related]
19. LRF Promotes Indirectly Advantageous Chromatin Conformation via
Chondrou V; Shaukat AN; Psarias G; Athanasopoulou K; Iliopoulou E; Damanaki A; Stathopoulos C; Sgourou A
Int J Mol Sci; 2022 Jun; 23(13):. PubMed ID: 35806029
[TBL] [Abstract][Full Text] [Related]
20. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]