BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 35619328)

  • 1. Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer.
    Xiao R; You L; Zhang L; Guo X; Guo E; Zhao F; Yang B; Li X; Fu Y; Lu F; Wang Z; Liu C; Peng W; Li W; Yang X; Dou Y; Liu J; Wang W; Qin T; Cui Y; Zhang X; Li F; Jin Y; Zeng Q; Wang B; Mills GB; Chen G; Sheng X; Sun C
    Adv Sci (Weinh); 2022 Jul; 9(21):e2105469. PubMed ID: 35619328
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling.
    Sheng X; Nenseth HZ; Qu S; Kuzu OF; Frahnow T; Simon L; Greene S; Zeng Q; Fazli L; Rennie PS; Mills IG; Danielsen H; Theis F; Patterson JB; Jin Y; Saatcioglu F
    Nat Commun; 2019 Jan; 10(1):323. PubMed ID: 30679434
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
    Han X; Zhou J; Zhang P; Song F; Jiang R; Li M; Xia F; Guo FJ
    Cell Signal; 2013 Nov; 25(11):2136-46. PubMed ID: 23816533
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in
    Zundell JA; Fukumoto T; Lin J; Fatkhudinov N; Nacarelli T; Kossenkov AV; Liu Q; Cassel J; Hu CA; Wu S; Zhang R
    Cancer Res; 2021 Oct; 81(20):5325-5335. PubMed ID: 34548333
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The endoplasmic reticulum stress sensor IRE1α protects cells from apoptosis induced by the coronavirus infectious bronchitis virus.
    Fung TS; Liao Y; Liu DX
    J Virol; 2014 Nov; 88(21):12752-64. PubMed ID: 25142592
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
    Blazanin N; Son J; Craig-Lucas AB; John CL; Breech KJ; Podolsky MA; Glick AB
    Proc Natl Acad Sci U S A; 2017 Sep; 114(37):9900-9905. PubMed ID: 28847931
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication.
    Su A; Wang H; Li Y; Wang X; Chen D; Wu Z
    Viruses; 2017 Aug; 9(9):. PubMed ID: 28832521
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism.
    Huang Y; Lin Q; Huo Z; Chen C; Zhou S; Ma X; Gao H; Lin Y; Li X; He J; Zhang P; Liu C
    J Virol; 2020 Nov; 94(23):. PubMed ID: 32967957
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
    Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
    Liu X; Guo GL; Kong B; Hilburn DB; Hubchak SC; Park S; LeCuyer B; Hsieh A; Wang L; Fang D; Green RM
    Hepatology; 2018 Jul; 68(1):304-316. PubMed ID: 29377207
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma.
    Mimura N; Fulciniti M; Gorgun G; Tai YT; Cirstea D; Santo L; Hu Y; Fabre C; Minami J; Ohguchi H; Kiziltepe T; Ikeda H; Kawano Y; French M; Blumenthal M; Tam V; Kertesz NL; Malyankar UM; Hokenson M; Pham T; Zeng Q; Patterson JB; Richardson PG; Munshi NC; Anderson KC
    Blood; 2012 Jun; 119(24):5772-81. PubMed ID: 22538852
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Augmented antitumor activity by olaparib plus AZD1775 in gastric cancer through disrupting DNA damage repair pathways and DNA damage checkpoint.
    Lin X; Chen D; Zhang C; Zhang X; Li Z; Dong B; Gao J; Shen L
    J Exp Clin Cancer Res; 2018 Jun; 37(1):129. PubMed ID: 29954437
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer.
    Lin J; Liu H; Fukumoto T; Zundell J; Yan Q; Tang CA; Wu S; Zhou W; Guo D; Karakashev S; Hu CA; Sarma K; Kossenkov AV; Zhang R
    Nat Commun; 2021 Sep; 12(1):5321. PubMed ID: 34493732
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival.
    Moore PC; Qi JY; Thamsen M; Ghosh R; Peng J; Gliedt MJ; Meza-Acevedo R; Warren RE; Hiniker A; Kim GE; Maly DJ; Backes BJ; Papa FR; Oakes SA
    Cancer Res; 2019 Dec; 79(24):6190-6203. PubMed ID: 31672843
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heat stress promotes the down-regulation of IRE1α in cells: An atypical modulation of the UPR pathway.
    Homma T; Fujii J
    Exp Cell Res; 2016 Nov; 349(1):128-138. PubMed ID: 27743894
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months.
    Leijen S; van Geel RM; Sonke GS; de Jong D; Rosenberg EH; Marchetti S; Pluim D; van Werkhoven E; Rose S; Lee MA; Freshwater T; Beijnen JH; Schellens JH
    J Clin Oncol; 2016 Dec; 34(36):4354-4361. PubMed ID: 27998224
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib.
    Yamashita Y; Morita S; Hosoi H; Kobata H; Kishimoto S; Ishibashi T; Mishima H; Kinoshita A; Backes BJ; Yoshiura KI; Papa FR; Sonoki T; Tamura S
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32878237
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress.
    Tay KH; Luan Q; Croft A; Jiang CC; Jin L; Zhang XD; Tseng HY
    Cell Signal; 2014 Feb; 26(2):287-94. PubMed ID: 24240056
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aqueous Extract of Descuraniae Semen Attenuates Lipopolysaccharide-Induced Inflammation and Apoptosis by Regulating the Proteasomal Degradation and IRE1α-Dependent Unfolded Protein Response in A549 Cells.
    Hsieh PC; Peng CK; Liu GT; Kuo CY; Tzeng IS; Wang MC; Lan CC; Huang KL
    Front Immunol; 2022; 13():916102. PubMed ID: 35812413
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1α (IRE1α) in human colon cancer cells.
    Shimodaira Y; Takahashi S; Kinouchi Y; Endo K; Shiga H; Kakuta Y; Kuroha M; Shimosegawa T
    Biochem Biophys Res Commun; 2014 Mar; 445(2):524-33. PubMed ID: 24565834
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.