134 related articles for article (PubMed ID: 35623388)
1. Discovery of a small-molecule inhibitor of the TRIP8b-HCN interaction with efficacy in neurons.
Han Y; Iyamu ID; Clutter MR; Mishra RK; Lyman KA; Zhou C; Michailidis I; Xia MY; Sharma H; Luan CH; Schiltz GE; Chetkovich DM
J Biol Chem; 2022 Jul; 298(7):102069. PubMed ID: 35623388
[TBL] [Abstract][Full Text] [Related]
2. HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects.
Han Y; Heuermann RJ; Lyman KA; Fisher D; Ismail QA; Chetkovich DM
Mol Psychiatry; 2017 Mar; 22(3):458-465. PubMed ID: 27400855
[TBL] [Abstract][Full Text] [Related]
3. Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.
Lewis AS; Vaidya SP; Blaiss CA; Liu Z; Stoub TR; Brager DH; Chen X; Bender RA; Estep CM; Popov AB; Kang CE; Van Veldhoven PP; Bayliss DA; Nicholson DA; Powell CM; Johnston D; Chetkovich DM
J Neurosci; 2011 May; 31(20):7424-40. PubMed ID: 21593326
[TBL] [Abstract][Full Text] [Related]
4. Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b.
Han Y; Lyman KA; Clutter M; Schiltz GE; Ismail QA; Cheng X; Luan CH; Chetkovich DM
J Vis Exp; 2016 Nov; (117):. PubMed ID: 27911380
[TBL] [Abstract][Full Text] [Related]
5. Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior.
Lyman KA; Han Y; Zhou C; Renteria I; Besing GL; Kurz JE; Chetkovich DM
Sci Transl Med; 2021 Nov; 13(621):eabl4580. PubMed ID: 34818058
[TBL] [Abstract][Full Text] [Related]
6. Identification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels.
Han Y; Lyman K; Clutter M; Schiltz GE; Ismail QA; Prados DB; Luan CH; Chetkovich DM
J Biomol Screen; 2015 Oct; 20(9):1124-31. PubMed ID: 26045196
[TBL] [Abstract][Full Text] [Related]
7. Trafficking and gating of hyperpolarization-activated cyclic nucleotide-gated channels are regulated by interaction with tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) and cyclic AMP at distinct sites.
Han Y; Noam Y; Lewis AS; Gallagher JJ; Wadman WJ; Baram TZ; Chetkovich DM
J Biol Chem; 2011 Jun; 286(23):20823-34. PubMed ID: 21504900
[TBL] [Abstract][Full Text] [Related]
8. The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels.
Han Y; Lyman KA; Foote KM; Chetkovich DM
Channels (Austin); 2020 Dec; 14(1):110-122. PubMed ID: 32189562
[TBL] [Abstract][Full Text] [Related]
9. Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
Saponaro A; Pauleta SR; Cantini F; Matzapetakis M; Hammann C; Donadoni C; Hu L; Thiel G; Banci L; Santoro B; Moroni A
Proc Natl Acad Sci U S A; 2014 Oct; 111(40):14577-82. PubMed ID: 25197093
[TBL] [Abstract][Full Text] [Related]
10. Activation of GABAB receptors ameliorates cognitive impairment via restoring the balance of HCN1/HCN2 surface expression in the hippocampal CA1 area in rats with chronic cerebral hypoperfusion.
Li CJ; Lu Y; Zhou M; Zong XG; Li C; Xu XL; Guo LJ; Lu Q
Mol Neurobiol; 2014 Oct; 50(2):704-20. PubMed ID: 24838625
[TBL] [Abstract][Full Text] [Related]
11. HCN channels: New targets for the design of an antidepressant with rapid effects.
Luo P; He G; Liu D
J Affect Disord; 2019 Feb; 245():764-770. PubMed ID: 30448761
[TBL] [Abstract][Full Text] [Related]
12. Rational design of a mutation to investigate the role of the brain protein TRIP8b in limiting the cAMP response of HCN channels in neurons.
Porro A; Binda A; Pisoni M; Donadoni C; Rivolta I; Saponaro A
J Gen Physiol; 2020 Sep; 152(9):. PubMed ID: 32633755
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function.
Foote KM; Lyman KA; Han Y; Michailidis IE; Heuermann RJ; Mandikian D; Trimmer JS; Swanson GT; Chetkovich DM
J Biol Chem; 2019 Oct; 294(43):15743-15758. PubMed ID: 31492750
[TBL] [Abstract][Full Text] [Related]
14. Characterization of Kv1.2-mediated outward current in TRIP8b-deficient mice.
Labbaf A; Dellin M; Komadowski M; Chetkovich DM; Decher N; Pape HC; Seebohm G; Budde T; Zobeiri M
Biol Chem; 2023 Mar; 404(4):291-302. PubMed ID: 36852869
[TBL] [Abstract][Full Text] [Related]
15. Neurophysiology of HCN channels: from cellular functions to multiple regulations.
He C; Chen F; Li B; Hu Z
Prog Neurobiol; 2014 Jan; 112():1-23. PubMed ID: 24184323
[TBL] [Abstract][Full Text] [Related]
16. Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels.
Lyman KA; Han Y; Heuermann RJ; Cheng X; Kurz JE; Lyman RE; Van Veldhoven PP; Chetkovich DM
J Biol Chem; 2017 Oct; 292(43):17718-17730. PubMed ID: 28887304
[TBL] [Abstract][Full Text] [Related]
17. Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
Bankston JR; Camp SS; DiMaio F; Lewis AS; Chetkovich DM; Zagotta WN
Proc Natl Acad Sci U S A; 2012 May; 109(20):7899-904. PubMed ID: 22550182
[TBL] [Abstract][Full Text] [Related]
18. Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements.
Saponaro A; Vallese F; Porro A; Clarke OB
Front Physiol; 2022; 13():998176. PubMed ID: 36225302
[TBL] [Abstract][Full Text] [Related]
19. TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels.
Huang Z; Lujan R; Martinez-Hernandez J; Lewis AS; Chetkovich DM; Shah MM
J Neurosci; 2012 Oct; 32(42):14835-48. PubMed ID: 23077068
[TBL] [Abstract][Full Text] [Related]
20. Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice.
Scherschel K; Bräuninger H; Mölders A; Erlenhardt N; Amin E; Jungen C; Pape U; Lindner D; Chetkovich DM; Klöcker N; Meyer C
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946275
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
