These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Ligandability of E3 Ligases for Targeted Protein Degradation Applications. Belcher BP; Ward CC; Nomura DK Biochemistry; 2023 Feb; 62(3):588-600. PubMed ID: 34473924 [TBL] [Abstract][Full Text] [Related]
7. Induced protein degradation for therapeutics: past, present, and future. Yoon H; Rutter JC; Li YD; Ebert BL J Clin Invest; 2024 Jan; 134(1):. PubMed ID: 38165043 [TBL] [Abstract][Full Text] [Related]
8. From Thalidomide to Rational Molecular Glue Design for Targeted Protein Degradation. Oleinikovas V; Gainza P; Ryckmans T; Fasching B; Thomä NH Annu Rev Pharmacol Toxicol; 2024 Jan; 64():291-312. PubMed ID: 37585660 [TBL] [Abstract][Full Text] [Related]
9. Biophysical and Computational Approaches to Study Ternary Complexes: A 'Cooperative Relationship' to Rationalize Targeted Protein Degradation. Ward JA; Perez-Lopez C; Mayor-Ruiz C Chembiochem; 2023 May; 24(10):e202300163. PubMed ID: 37018140 [TBL] [Abstract][Full Text] [Related]
10. Comparative analysis of biophysical methods for monitoring protein proximity induction in the development of small molecule degraders. Przytulski K; Glaza P; Brach K; Sagan M; Statkiewicz G; Klajn J; Walczak MJ Biochim Biophys Acta Gen Subj; 2023 Sep; 1867(9):130398. PubMed ID: 37301332 [TBL] [Abstract][Full Text] [Related]
12. Molecular Glues: The Adhesive Connecting Targeted Protein Degradation to the Clinic. Sasso JM; Tenchov R; Wang D; Johnson LS; Wang X; Zhou QA Biochemistry; 2023 Feb; 62(3):601-623. PubMed ID: 35856839 [TBL] [Abstract][Full Text] [Related]
13. Emerging strategies for prospective discovery of molecular glue degraders. Wang B; Cao S; Zheng N Curr Opin Struct Biol; 2024 Jun; 86():102811. PubMed ID: 38598983 [TBL] [Abstract][Full Text] [Related]
14. Key Considerations in Targeted Protein Degradation Drug Discovery and Development. Qin L; Dai H; Wang J Front Chem; 2022; 10():934337. PubMed ID: 35978859 [TBL] [Abstract][Full Text] [Related]
15. Advancing targeted protein degrader discovery by measuring cereblon engagement in cells. Zerfas BL; Huerta F; Liu H; Du G; Gray NS; Jones LH; Nowak RP Methods Enzymol; 2023; 681():169-188. PubMed ID: 36764756 [TBL] [Abstract][Full Text] [Related]
16. Driving E3 Ligase Substrate Specificity for Targeted Protein Degradation: Lessons from Nature and the Laboratory. Cowan AD; Ciulli A Annu Rev Biochem; 2022 Jun; 91():295-319. PubMed ID: 35320687 [TBL] [Abstract][Full Text] [Related]