256 related articles for article (PubMed ID: 35628602)
1. The Small Molecule GAL-201 Efficiently Detoxifies Soluble Amyloid β Oligomers: New Approach towards Oral Disease-Modifying Treatment of Alzheimer's Disease.
Russ H; Mazzanti M; Parsons C; Riemann K; Gebauer A; Rammes G
Int J Mol Sci; 2022 May; 23(10):. PubMed ID: 35628602
[TBL] [Abstract][Full Text] [Related]
2. MRZ-99030 - A novel modulator of Aβ aggregation: II - Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice.
Rammes G; Gravius A; Ruitenberg M; Wegener N; Chambon C; Sroka-Saidi K; Jeggo R; Staniaszek L; Spanswick D; O'Hare E; Palmer P; Kim EM; Bywalez W; Egger V; Parsons CG
Neuropharmacology; 2015 May; 92():170-82. PubMed ID: 25637092
[TBL] [Abstract][Full Text] [Related]
3. The Aβ aggregation modulator MRZ-99030 prevents and even reverses synaptotoxic effects of Aβ
Rammes G; Parsons CG
Neuropharmacology; 2020 Nov; 179():108267. PubMed ID: 32758564
[TBL] [Abstract][Full Text] [Related]
4. Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease.
Scott-McKean JJ; Surewicz K; Choi JK; Ruffin VA; Salameh AI; Nieznanski K; Costa ACS; Surewicz WK
Neurobiol Dis; 2016 Jul; 91():124-131. PubMed ID: 26949218
[TBL] [Abstract][Full Text] [Related]
5. Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer's disease.
Li S; Jin M; Liu L; Dang Y; Ostaszewski BL; Selkoe DJ
Acta Neuropathol Commun; 2018 Nov; 6(1):121. PubMed ID: 30409172
[TBL] [Abstract][Full Text] [Related]
6. Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.
Rammes G; Hasenjäger A; Sroka-Saidi K; Deussing JM; Parsons CG
Neuropharmacology; 2011 May; 60(6):982-90. PubMed ID: 21310164
[TBL] [Abstract][Full Text] [Related]
7. Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior.
Selkoe DJ
Behav Brain Res; 2008 Sep; 192(1):106-13. PubMed ID: 18359102
[TBL] [Abstract][Full Text] [Related]
8. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.
Walsh DM; Klyubin I; Fadeeva JV; Cullen WK; Anwyl R; Wolfe MS; Rowan MJ; Selkoe DJ
Nature; 2002 Apr; 416(6880):535-9. PubMed ID: 11932745
[TBL] [Abstract][Full Text] [Related]
9. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers.
Laurén J; Gimbel DA; Nygaard HB; Gilbert JW; Strittmatter SM
Nature; 2009 Feb; 457(7233):1128-32. PubMed ID: 19242475
[TBL] [Abstract][Full Text] [Related]
10. Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
Yang T; Li S; Xu H; Walsh DM; Selkoe DJ
J Neurosci; 2017 Jan; 37(1):152-163. PubMed ID: 28053038
[TBL] [Abstract][Full Text] [Related]
11. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity.
Izzo NJ; Xu J; Zeng C; Kirk MJ; Mozzoni K; Silky C; Rehak C; Yurko R; Look G; Rishton G; Safferstein H; Cruchaga C; Goate A; Cahill MA; Arancio O; Mach RH; Craven R; Head E; LeVine H; Spires-Jones TL; Catalano SM
PLoS One; 2014; 9(11):e111899. PubMed ID: 25390692
[TBL] [Abstract][Full Text] [Related]
12. Tau and Amyloid β Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiation
Ondrejcak T; Klyubin I; Hu NW; O'Malley TT; Corbett GT; Winters R; Perkinton MS; Billinton A; Prenderville JA; Walsh DM; Rowan MJ
J Neurosci; 2023 Aug; 43(32):5870-5879. PubMed ID: 37491315
[TBL] [Abstract][Full Text] [Related]
13. Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein.
Barry AE; Klyubin I; Mc Donald JM; Mably AJ; Farrell MA; Scott M; Walsh DM; Rowan MJ
J Neurosci; 2011 May; 31(20):7259-63. PubMed ID: 21593310
[TBL] [Abstract][Full Text] [Related]
14. Protective effects of EphB2 on Aβ1-42 oligomer-induced neurotoxicity and synaptic NMDA receptor signaling in hippocampal neurons.
Geng D; Kang L; Su Y; Jia J; Ma J; Li S; Du J; Cui H
Neurochem Int; 2013 Oct; 63(4):283-90. PubMed ID: 23831214
[TBL] [Abstract][Full Text] [Related]
15. Alzheimer's protection effect of A673T mutation may be driven by lower Aβ oligomer binding affinity.
Limegrover CS; LeVine H; Izzo NJ; Yurko R; Mozzoni K; Rehak C; Sadlek K; Safferstein H; Catalano SM
J Neurochem; 2021 May; 157(4):1316-1330. PubMed ID: 33025581
[TBL] [Abstract][Full Text] [Related]
16. Neuroprotective Effects of Ferruginol, Jatrophone, and Junicedric Acid Against Amyloid-β Injury in Hippocampal Neurons.
Zolezzi JM; Lindsay CB; Serrano FG; Ureta RC; Theoduloz C; Schmeda-Hirschmann G; Inestrosa NC
J Alzheimers Dis; 2018; 63(2):705-723. PubMed ID: 29660932
[TBL] [Abstract][Full Text] [Related]
17. Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes.
Micci MA; Krishnan B; Bishop E; Zhang WR; Guptarak J; Grant A; Zolochevska O; Tumurbaatar B; Franklin W; Marino C; Widen SG; Luthra A; Kernie SG; Taglialatela G
Mol Neurodegener; 2019 Jun; 14(1):25. PubMed ID: 31200742
[TBL] [Abstract][Full Text] [Related]
18. Astrocytic glutamatergic transporters are involved in Aβ-induced synaptic dysfunction.
Huang S; Tong H; Lei M; Zhou M; Guo W; Li G; Tang X; Li Z; Mo M; Zhang X; Chen X; Cen L; Wei L; Xiao Y; Li K; Huang Q; Yang X; Liu W; Zhang L; Qu S; Li S; Xu P
Brain Res; 2018 Jan; 1678():129-137. PubMed ID: 29066369
[TBL] [Abstract][Full Text] [Related]
19. Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.
Townsend M; Shankar GM; Mehta T; Walsh DM; Selkoe DJ
J Physiol; 2006 Apr; 572(Pt 2):477-92. PubMed ID: 16469784
[TBL] [Abstract][Full Text] [Related]
20. The Single Toxin Origin of Alzheimer's Disease and Other Neurodegenerative Disorders Enables Targeted Approach to Treatment and Prevention.
Tolar M; Hey JA; Power A; Abushakra S
Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38473975
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
