These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 35634291)

  • 1. Genome Replication Is Associated With Release of Immunogenic DNA Waste.
    Schubert N; Schumann T; Daum E; Flade K; Ge Y; Hagedorn L; Edelmann W; Müller L; Schmitz M; Kuut G; Hornung V; Behrendt R; Roers A
    Front Immunol; 2022; 13():880413. PubMed ID: 35634291
    [TBL] [Abstract][Full Text] [Related]  

  • 2. cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model.
    Xiao N; Wei J; Xu S; Du H; Huang M; Zhang S; Ye W; Sun L; Chen Q
    J Autoimmun; 2019 Jun; 100():84-94. PubMed ID: 30872080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.
    Gray EE; Treuting PM; Woodward JJ; Stetson DB
    J Immunol; 2015 Sep; 195(5):1939-43. PubMed ID: 26223655
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling.
    Shim A; Luan X; Zhou W; Crow YJ; Maciejowski J
    Hum Mol Genet; 2024 Sep; 33(18):1555-1566. PubMed ID: 38796715
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
    Li P; Du J; Goodier JL; Hou J; Kang J; Kazazian HH; Zhao K; Yu XF
    Nucleic Acids Res; 2017 May; 45(8):4619-4631. PubMed ID: 28334850
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
    Gao D; Li T; Li XD; Chen X; Li QZ; Wight-Carter M; Chen ZJ
    Proc Natl Acad Sci U S A; 2015 Oct; 112(42):E5699-705. PubMed ID: 26371324
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner.
    Ablasser A; Hemmerling I; Schmid-Burgk JL; Behrendt R; Roers A; Hornung V
    J Immunol; 2014 Jun; 192(12):5993-7. PubMed ID: 24813208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. cGAS activation in classical dendritic cells causes autoimmunity in TREX1-deficient mice.
    Li T; Yum S; Wu J; Li M; Deng Y; Sun L; Zuo X; Chen ZJ
    Proc Natl Acad Sci U S A; 2024 Sep; 121(38):e2411747121. PubMed ID: 39254994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing.
    Zhou W; Mohr L; Maciejowski J; Kranzusch PJ
    Mol Cell; 2021 Feb; 81(4):739-755.e7. PubMed ID: 33606975
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease.
    Mathavarajah S; Dellaire G
    Biochem Cell Biol; 2024 Feb; 102(1):38-46. PubMed ID: 37643478
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.
    Achleitner M; Kleefisch M; Hennig A; Peschke K; Polikarpova A; Oertel R; Gabriel B; Schulze L; Lindeman D; Gerbaulet A; Fiebig U; Lee-Kirsch MA; Roers A; Behrendt R
    J Immunol; 2017 Oct; 199(7):2261-2269. PubMed ID: 28835460
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutations in the non-catalytic polyproline motif destabilize TREX1 and amplify cGAS-STING signaling.
    Shim A; Luan X; Zhou W; Crow Y; Maciejowski J
    bioRxiv; 2024 Jan; ():. PubMed ID: 38260344
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
    Mackenzie KJ; Carroll P; Lettice L; Tarnauskaitė Ž; Reddy K; Dix F; Revuelta A; Abbondati E; Rigby RE; Rabe B; Kilanowski F; Grimes G; Fluteau A; Devenney PS; Hill RE; Reijns MA; Jackson AP
    EMBO J; 2016 Apr; 35(8):831-44. PubMed ID: 26903602
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
    Orebaugh CD; Fye JM; Harvey S; Hollis T; Perrino FW
    J Biol Chem; 2011 Nov; 286(46):40246-54. PubMed ID: 21937424
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Photosensitivity and cGAS-Dependent IFN-1 Activation in Patients with Lupus and TREX1 Deficiency.
    Berndt N; Wolf C; Fischer K; Cura Costa E; Knuschke P; Zimmermann N; Schmidt F; Merkel M; Chara O; Lee-Kirsch MA; Günther C
    J Invest Dermatol; 2022 Mar; 142(3 Pt A):633-640.e6. PubMed ID: 34400195
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIV-1 Activation of Innate Immunity Depends Strongly on the Intracellular Level of TREX1 and Sensing of Incomplete Reverse Transcription Products.
    Kumar S; Morrison JH; Dingli D; Poeschla E
    J Virol; 2018 Aug; 92(16):. PubMed ID: 29769349
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SAMHD1 and the innate immune response to cytosolic DNA during DNA replication.
    Coquel F; Neumayer C; Lin YL; Pasero P
    Curr Opin Immunol; 2019 Feb; 56():24-30. PubMed ID: 30292848
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.
    Fye JM; Orebaugh CD; Coffin SR; Hollis T; Perrino FW
    J Biol Chem; 2011 Sep; 286(37):32373-82. PubMed ID: 21808053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aicardi-Goutières syndrome: clues from the RNase H2 knock-out mouse.
    Rabe B
    J Mol Med (Berl); 2013 Nov; 91(11):1235-40. PubMed ID: 23744109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of Cyclic GMP-AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1-Deficient Mice.
    An J; Woodward JJ; Lai W; Minie M; Sun X; Tanaka L; Snyder JM; Sasaki T; Elkon KB
    Arthritis Rheumatol; 2018 Nov; 70(11):1807-1819. PubMed ID: 29781188
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.