BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 35640974)

  • 1. Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation.
    Bufton JC; Powers KT; Szeto JA; Toelzer C; Berger I; Schaffitzel C
    Nucleic Acids Res; 2022 Jun; 50(10):5934-5947. PubMed ID: 35640974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay.
    Wallmeroth D; Lackmann JW; Kueckelmann S; Altmüller J; Dieterich C; Boehm V; Gehring NH
    EMBO J; 2022 May; 41(10):e109191. PubMed ID: 35451084
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mammalian UPF3A and UPF3B can activate nonsense-mediated mRNA decay independently of their exon junction complex binding.
    Yi Z; Arvola RM; Myers S; Dilsavor CN; Abu Alhasan R; Carter BN; Patton RD; Bundschuh R; Singh G
    EMBO J; 2022 May; 41(10):e109202. PubMed ID: 35451102
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A UPF3-mediated regulatory switch that maintains RNA surveillance.
    Chan WK; Bhalla AD; Le Hir H; Nguyen LS; Huang L; Gécz J; Wilkinson MF
    Nat Struct Mol Biol; 2009 Jul; 16(7):747-53. PubMed ID: 19503078
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of copy number variants involving nonsense-mediated mRNA decay pathway genes to neuro-developmental disorders.
    Nguyen LS; Kim HG; Rosenfeld JA; Shen Y; Gusella JF; Lacassie Y; Layman LC; Shaffer LG; Gécz J
    Hum Mol Genet; 2013 May; 22(9):1816-25. PubMed ID: 23376982
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability.
    Nguyen LS; Jolly L; Shoubridge C; Chan WK; Huang L; Laumonnier F; Raynaud M; Hackett A; Field M; Rodriguez J; Srivastava AK; Lee Y; Long R; Addington AM; Rapoport JL; Suren S; Hahn CN; Gamble J; Wilkinson MF; Corbett MA; Gecz J
    Mol Psychiatry; 2012 Nov; 17(11):1103-15. PubMed ID: 22182939
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional roles of human Up-frameshift suppressor 3 (UPF3) proteins: From nonsense-mediated mRNA decay to neurodevelopmental disorders.
    Deka B; Chandra P; Singh KK
    Biochimie; 2021 Jan; 180():10-22. PubMed ID: 33132159
    [TBL] [Abstract][Full Text] [Related]  

  • 8. UPF3A is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cells.
    Chen C; Shen Y; Li L; Ren Y; Wang ZQ; Li T
    Life Sci Alliance; 2023 Jun; 6(6):. PubMed ID: 36997282
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A highly conserved region essential for NMD in the Upf2 N-terminal domain.
    Fourati Z; Roy B; Millan C; Coureux PD; Kervestin S; van Tilbeurgh H; He F; Usón I; Jacobson A; Graille M
    J Mol Biol; 2014 Nov; 426(22):3689-3702. PubMed ID: 25277656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex.
    López-Perrote A; Castaño R; Melero R; Zamarro T; Kurosawa H; Ohnishi T; Uchiyama A; Aoyagi K; Buchwald G; Kataoka N; Yamashita A; Llorca O
    Nucleic Acids Res; 2016 Feb; 44(4):1909-23. PubMed ID: 26740584
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3.
    Kadlec J; Izaurralde E; Cusack S
    Nat Struct Mol Biol; 2004 Apr; 11(4):330-7. PubMed ID: 15004547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth.
    Jolly LA; Homan CC; Jacob R; Barry S; Gecz J
    Hum Mol Genet; 2013 Dec; 22(23):4673-87. PubMed ID: 23821644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2.
    Clerici M; Deniaud A; Boehm V; Gehring NH; Schaffitzel C; Cusack S
    Nucleic Acids Res; 2014 Feb; 42(4):2673-86. PubMed ID: 24271394
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.
    Metze S; Herzog VA; Ruepp MD; Mühlemann O
    RNA; 2013 Oct; 19(10):1432-48. PubMed ID: 23962664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.
    Shum EY; Jones SH; Shao A; Chousal JN; Krause MD; Chan WK; Lou CH; Espinoza JL; Song HW; Phan MH; Ramaiah M; Huang L; McCarrey JR; Peterson KJ; De Rooij DG; Cook-Andersen H; Wilkinson MF
    Cell; 2016 Apr; 165(2):382-95. PubMed ID: 27040500
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A synonymous UPF3B variant causing a speech disorder implicates NMD as a regulator of neurodevelopmental disorder gene networks.
    Domingo D; Nawaz U; Corbett M; Espinoza JL; Tatton-Brown K; Coman D; Wilkinson MF; Gecz J; Jolly LA
    Hum Mol Genet; 2020 Aug; 29(15):2568-2578. PubMed ID: 32667670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.
    Huang L; Low A; Damle SS; Keenan MM; Kuntz S; Murray SF; Monia BP; Guo S
    Genome Biol; 2018 Jan; 19(1):4. PubMed ID: 29334995
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nonsense in the testis: multiple roles for nonsense-mediated decay revealed in male reproduction.
    MacDonald CC; Grozdanov PN
    Biol Reprod; 2017 May; 96(5):939-947. PubMed ID: 28444146
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.
    Chamieh H; Ballut L; Bonneau F; Le Hir H
    Nat Struct Mol Biol; 2008 Jan; 15(1):85-93. PubMed ID: 18066079
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex.
    Buchwald G; Ebert J; Basquin C; Sauliere J; Jayachandran U; Bono F; Le Hir H; Conti E
    Proc Natl Acad Sci U S A; 2010 Jun; 107(22):10050-5. PubMed ID: 20479275
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.