These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 35646935)

  • 21. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.
    Bennett CL; Dastidar SG; Ling SC; Malik B; Ashe T; Wadhwa M; Miller DB; Lee C; Mitchell MB; van Es MA; Grunseich C; Chen Y; Sopher BL; Greensmith L; Cleveland DW; La Spada AR
    Acta Neuropathol; 2018 Sep; 136(3):425-443. PubMed ID: 29725819
    [TBL] [Abstract][Full Text] [Related]  

  • 22. TDP-43 α-helical structure tunes liquid-liquid phase separation and function.
    Conicella AE; Dignon GL; Zerze GH; Schmidt HB; D'Ordine AM; Kim YC; Rohatgi R; Ayala YM; Mittal J; Fawzi NL
    Proc Natl Acad Sci U S A; 2020 Mar; 117(11):5883-5894. PubMed ID: 32132204
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
    Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
    Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice.
    Perera ND; Sheean RK; Crouch PJ; White AR; Horne MK; Turner BJ
    Hum Mol Genet; 2016 Sep; 25(18):4080-4093. PubMed ID: 27466204
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.
    White MA; Lin Z; Kim E; Henstridge CM; Pena Altamira E; Hunt CK; Burchill E; Callaghan I; Loreto A; Brown-Wright H; Mead R; Simmons C; Cash D; Coleman MP; Sreedharan J
    Acta Neuropathol Commun; 2019 Oct; 7(1):166. PubMed ID: 31661035
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Pathophysiological implications of RNP granules in frontotemporal dementia and ALS.
    Desai P; Bandopadhyay R
    Neurochem Int; 2020 Nov; 140():104819. PubMed ID: 32763254
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.
    Ling SC
    Neural Plast; 2018; 2018():8413496. PubMed ID: 29755516
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis.
    Pisciottani A; Croci L; Lauria F; Marullo C; Savino E; Ambrosi A; Podini P; Marchioretto M; Casoni F; Cremona O; Taverna S; Quattrini A; Cioni JM; Viero G; Codazzi F; Consalez GG
    Front Cell Neurosci; 2023; 17():1253543. PubMed ID: 38026702
    [TBL] [Abstract][Full Text] [Related]  

  • 29. TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
    Mackenzie IR; Nicholson AM; Sarkar M; Messing J; Purice MD; Pottier C; Annu K; Baker M; Perkerson RB; Kurti A; Matchett BJ; Mittag T; Temirov J; Hsiung GR; Krieger C; Murray ME; Kato M; Fryer JD; Petrucelli L; Zinman L; Weintraub S; Mesulam M; Keith J; Zivkovic SA; Hirsch-Reinshagen V; Roos RP; Züchner S; Graff-Radford NR; Petersen RC; Caselli RJ; Wszolek ZK; Finger E; Lippa C; Lacomis D; Stewart H; Dickson DW; Kim HJ; Rogaeva E; Bigio E; Boylan KB; Taylor JP; Rademakers R
    Neuron; 2017 Aug; 95(4):808-816.e9. PubMed ID: 28817800
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Granulins modulate liquid-liquid phase separation and aggregation of the prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43.
    Bhopatkar AA; Uversky VN; Rangachari V
    J Biol Chem; 2020 Feb; 295(8):2506-2519. PubMed ID: 31911437
    [TBL] [Abstract][Full Text] [Related]  

  • 31. TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.
    Johnson BS; Snead D; Lee JJ; McCaffery JM; Shorter J; Gitler AD
    J Biol Chem; 2009 Jul; 284(30):20329-39. PubMed ID: 19465477
    [TBL] [Abstract][Full Text] [Related]  

  • 32. ALS-linked mutations impair UBQLN2 stress-induced biomolecular condensate assembly in cells.
    Riley JF; Fioramonti PJ; Rusnock AK; Hehnly H; Castañeda CA
    J Neurochem; 2021 Oct; 159(1):145-155. PubMed ID: 34129687
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Disease mutations in the prion-like domains of hnRNPA1 and hnRNPA2/B1 introduce potent steric zippers that drive excess RNP granule assembly.
    Shorter J; Taylor JP
    Rare Dis; 2013; 1():e25200. PubMed ID: 25002999
    [TBL] [Abstract][Full Text] [Related]  

  • 34. An Emerging Role for Post-translational Modifications in Regulating RNP Condensates in the Germ Line.
    Schisa JA; Elaswad MT
    Front Mol Biosci; 2021; 8():658020. PubMed ID: 33898525
    [TBL] [Abstract][Full Text] [Related]  

  • 35. ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.
    Murakami T; Qamar S; Lin JQ; Schierle GS; Rees E; Miyashita A; Costa AR; Dodd RB; Chan FT; Michel CH; Kronenberg-Versteeg D; Li Y; Yang SP; Wakutani Y; Meadows W; Ferry RR; Dong L; Tartaglia GG; Favrin G; Lin WL; Dickson DW; Zhen M; Ron D; Schmitt-Ulms G; Fraser PE; Shneider NA; Holt C; Vendruscolo M; Kaminski CF; St George-Hyslop P
    Neuron; 2015 Nov; 88(4):678-90. PubMed ID: 26526393
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.
    Fang MY; Markmiller S; Vu AQ; Javaherian A; Dowdle WE; Jolivet P; Bushway PJ; Castello NA; Baral A; Chan MY; Linsley JW; Linsley D; Mercola M; Finkbeiner S; Lecuyer E; Lewcock JW; Yeo GW
    Neuron; 2019 Sep; 103(5):802-819.e11. PubMed ID: 31272829
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
    Konopka A; Whelan DR; Jamali MS; Perri E; Shahheydari H; Toth RP; Parakh S; Robinson T; Cheong A; Mehta P; Vidal M; Ragagnin AMG; Khizhnyak I; Jagaraj CJ; Galper J; Grima N; Deva A; Shadfar S; Nicholson GA; Yang S; Cutts SM; Horejsi Z; Bell TDM; Walker AK; Blair IP; Atkin JD
    Mol Neurodegener; 2020 Sep; 15(1):51. PubMed ID: 32907630
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS.
    Coyne AN; Zaepfel BL; Zarnescu DC
    Front Cell Neurosci; 2017; 11():243. PubMed ID: 28860970
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Granulostasis: Protein Quality Control of RNP Granules.
    Alberti S; Mateju D; Mediani L; Carra S
    Front Mol Neurosci; 2017; 10():84. PubMed ID: 28396624
    [TBL] [Abstract][Full Text] [Related]  

  • 40. ALS-Linked A315T and A315E Mutations Enhance β-Barrel Formation of the TDP-43
    Liu X; Li X; Qiao Q; Li F; Wei G
    ACS Chem Neurosci; 2023 Apr; 14(7):1310-1320. PubMed ID: 36888995
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.