BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 35652295)

  • 1. Cancer-associated mutations in SF3B1 disrupt the interaction between SF3B1 and DDX42.
    Zhao B; Li Z; Qian R; Liu G; Fan M; Liang Z; Hu X; Wan Y
    J Biochem; 2022 Jul; 172(2):117-126. PubMed ID: 35652295
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.
    Yang F; Bian T; Zhan X; Chen Z; Xing Z; Larsen NA; Zhang X; Shi Y
    Nat Commun; 2023 Feb; 14(1):897. PubMed ID: 36797247
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SF3B1/Hsh155 HEAT motif mutations affect interaction with the spliceosomal ATPase Prp5, resulting in altered branch site selectivity in pre-mRNA splicing.
    Tang Q; Rodriguez-Santiago S; Wang J; Pu J; Yuste A; Gupta V; Moldón A; Xu YZ; Query CC
    Genes Dev; 2016 Dec; 30(24):2710-2723. PubMed ID: 28087715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeast.
    Carrocci TJ; Zoerner DM; Paulson JC; Hoskins AA
    Nucleic Acids Res; 2017 May; 45(8):4837-4852. PubMed ID: 28062854
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SF3B1 mutations constitute a novel therapeutic target in breast cancer.
    Maguire SL; Leonidou A; Wai P; Marchiò C; Ng CK; Sapino A; Salomon AV; Reis-Filho JS; Weigelt B; Natrajan RC
    J Pathol; 2015 Mar; 235(4):571-80. PubMed ID: 25424858
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impact of cancer-associated mutations in Hsh155/SF3b1 HEAT repeats 9-12 on pre-mRNA splicing in Saccharomyces cerevisiae.
    Kaur H; Groubert B; Paulson JC; McMillan S; Hoskins AA
    PLoS One; 2020; 15(4):e0229315. PubMed ID: 32320410
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the aberrant splicing of DVL2 induced by cancer-associated SF3B1 mutation.
    Zhao B; Hu X; Zhou Y; Shi Y; Qian R; Wan Y
    Biochem Biophys Res Commun; 2021 Mar; 546():21-28. PubMed ID: 33561744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1.
    Zhang J; Ali AM; Lieu YK; Liu Z; Gao J; Rabadan R; Raza A; Mukherjee S; Manley JL
    Mol Cell; 2019 Oct; 76(1):82-95.e7. PubMed ID: 31474574
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells.
    Dolatshad H; Pellagatti A; Fernandez-Mercado M; Yip BH; Malcovati L; Attwood M; Przychodzen B; Sahgal N; Kanapin AA; Lockstone H; Scifo L; Vandenberghe P; Papaemmanuil E; Smith CW; Campbell PJ; Ogawa S; Maciejewski JP; Cazzola M; Savage KI; Boultwood J
    Leukemia; 2015 May; 29(5):1092-103. PubMed ID: 25428262
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3' Splice Site Selection through Use of a Different Branch Point.
    Darman RB; Seiler M; Agrawal AA; Lim KH; Peng S; Aird D; Bailey SL; Bhavsar EB; Chan B; Colla S; Corson L; Feala J; Fekkes P; Ichikawa K; Keaney GF; Lee L; Kumar P; Kunii K; MacKenzie C; Matijevic M; Mizui Y; Myint K; Park ES; Puyang X; Selvaraj A; Thomas MP; Tsai J; Wang JY; Warmuth M; Yang H; Zhu P; Garcia-Manero G; Furman RR; Yu L; Smith PG; Buonamici S
    Cell Rep; 2015 Nov; 13(5):1033-45. PubMed ID: 26565915
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the aberrant splicing of MAP3K7 induced by cancer-associated SF3B1 mutation.
    Li Z; Zhao B; Shi Y; Liang Y; Qian R; Wan Y
    J Biochem; 2021 Sep; 170(1):69-77. PubMed ID: 33751071
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigating the Molecular Mechanism of H3B-8800: A Splicing Modulator Inducing Preferential Lethality in Spliceosome-Mutant Cancers.
    Spinello A; Borišek J; Malcovati L; Magistrato A
    Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681880
    [TBL] [Abstract][Full Text] [Related]  

  • 13. U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing.
    Choi N; Liu Y; Oh J; Ha J; Zheng X; Shen H
    Cells; 2020 Dec; 9(12):. PubMed ID: 33317029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SF3B1 mutations are associated with alternative splicing in uveal melanoma.
    Furney SJ; Pedersen M; Gentien D; Dumont AG; Rapinat A; Desjardins L; Turajlic S; Piperno-Neumann S; de la Grange P; Roman-Roman S; Stern MH; Marais R
    Cancer Discov; 2013 Oct; 3(10):1122-1129. PubMed ID: 23861464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular architecture of the human 17S U2 snRNP.
    Zhang Z; Will CL; Bertram K; Dybkov O; Hartmuth K; Agafonov DE; Hofele R; Urlaub H; Kastner B; Lührmann R; Stark H
    Nature; 2020 Jul; 583(7815):310-313. PubMed ID: 32494006
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SF3B1 association with chromatin determines splicing outcomes.
    Kfir N; Lev-Maor G; Glaich O; Alajem A; Datta A; Sze SK; Meshorer E; Ast G
    Cell Rep; 2015 Apr; 11(4):618-29. PubMed ID: 25892229
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction.
    Talkish J; Igel H; Hunter O; Horner SW; Jeffery NN; Leach JR; Jenkins JL; Kielkopf CL; Ares M
    RNA; 2019 Aug; 25(8):1020-1037. PubMed ID: 31110137
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
    Loerch S; Leach JR; Horner SW; Maji D; Jenkins JL; Pulvino MJ; Kielkopf CL
    J Biol Chem; 2019 Feb; 294(8):2892-2902. PubMed ID: 30567737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies.
    Benbarche S; Pineda JMB; Galvis LB; Biswas J; Liu B; Wang E; Zhang Q; Hogg SJ; Lyttle K; Dahi A; Lewis AM; Sarchi M; Rahman J; Fox N; Ai Y; Mehta S; Garippa R; Ortiz-Pacheco J; Li Z; Monetti M; Stanley RF; Doulatov S; Bradley RK; Abdel-Wahab O
    Mol Cell; 2024 May; 84(10):1886-1903.e10. PubMed ID: 38688280
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts.
    Mupo A; Seiler M; Sathiaseelan V; Pance A; Yang Y; Agrawal AA; Iorio F; Bautista R; Pacharne S; Tzelepis K; Manes N; Wright P; Papaemmanuil E; Kent DG; Campbell PC; Buonamici S; Bolli N; Vassiliou GS
    Leukemia; 2017 Mar; 31(3):720-727. PubMed ID: 27604819
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.