BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 35661529)

  • 1. Design, semi-synthesis and bioactivity evaluation of novel podophyllotoxin derivatives as potent anti-tumor agents.
    Sun W; Sun F; Meng J; Cao X; Zhao S; Wang C; Li L; Jiang P
    Bioorg Chem; 2022 Sep; 126():105906. PubMed ID: 35661529
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ester derivatives obtained by C-ring modification of podophyllotoxin induce apoptosis and inhibited proliferation in PC-3M cells via down-regulation of PI3K/Akt signaling pathway.
    Zhao Y; Li D; Wei M; Du R; Yan Z
    Bioorg Med Chem Lett; 2021 Aug; 46():128174. PubMed ID: 34098082
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
    Lin H; Ai D; Liu Q; Wang X; Gao J; Chen Q; Ruan L; Tao Y; Gao J; Wang L
    J Nat Prod; 2023 Jul; 86(7):1844-1854. PubMed ID: 37395092
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of cytotoxic activity of novel podophyllotoxin derivatives incorporating piperazinyl-cinnamic amide moieties.
    Zhang X; Yang T; Jin X; Lin K; Dai X; Gao T; Huang G; Fan M; Ma L; Liu Z; Cao J
    Bioorg Chem; 2022 Jun; 123():105761. PubMed ID: 35358823
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton.
    Zhang C; Yang N; Yang CH; Ding HS; Luo C; Zhang Y; Wu MJ; Zhang XW; Shen X; Jiang HL; Meng LH; Ding J
    PLoS One; 2009; 4(3):e4881. PubMed ID: 19293927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ; Sun WX; Wang X; Zhang YH; Qiu HY; Qi JL; Pang YJ; Lu GH; Wang XM; Yu FG; Yang YH
    Chem Biol Drug Des; 2017 Aug; 90(2):236-243. PubMed ID: 28079286
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ester derivatives obtained by C-ring modification of podophyllotoxin-induced apoptosis and inhibited proliferation in Hemangioma Endothelial Cells via downregulation of PI3K/Akt signaling pathway.
    Zhao Y; Li D; Han Y; Wang H; Du R; Yan Z
    Chem Biol Drug Des; 2022 Jun; 99(6):828-838. PubMed ID: 35184389
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological activity evaluation of podophyllotoxin-linked bile acid derivatives as potential anti-liver cancer agents.
    Cai DS; Lou SY; Huo S; Yang YQ; Gao F; Pi WM; Chen KD; Wang C; Yang XY; Jiao JY; Xu B; Wang PL; Lei HM
    Bioorg Chem; 2022 Nov; 128():106066. PubMed ID: 35964500
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, Synthesis and Bioactivity Evaluation of Novel Chalcone Derivatives Possessing Tryptophan Moiety with Dual Activities of Anti-Cancer and Partially Restoring the Proliferation of Normal Kidney Cells Pre-Treated with Cisplatin.
    He M; Yu M; Li C; Meng X; Su J; Zhu Y; Yao R
    Anticancer Agents Med Chem; 2022; 22(10):1945-1961. PubMed ID: 34674626
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of podophyllotoxin derivatives as selective antitumor agents.
    Wu GR; Xu B; Yang YQ; Zhang XY; Fang K; Ma T; Wang H; Xue NN; Chen M; Guo WB; Jia XH; Wang PL; Lei HM
    Eur J Med Chem; 2018 Jul; 155():183-196. PubMed ID: 29886322
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combretastatin A4 Regulates Proliferation, Migration, Invasion, and Apoptosis of Thyroid Cancer Cells via PI3K/Akt Signaling Pathway.
    Liang W; Lai Y; Zhu M; Huang S; Feng W; Gu X
    Med Sci Monit; 2016 Dec; 22():4911-4917. PubMed ID: 27966519
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
    Ma Y; Yang X; Han H; Wen Z; Yang M; Zhang Y; Fu J; Wang X; Yin T; Lu G; Qi J; Lin H; Wang X; Yang Y
    Bioorg Chem; 2021 Jun; 111():104872. PubMed ID: 33838560
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway.
    Kamal A; Rao AV; Nayak VL; Reddy NV; Swapna K; Ramakrishna G; Alvala M
    Org Biomol Chem; 2014 Dec; 12(48):9864-80. PubMed ID: 25354805
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
    Ma Z; Yang J; Yang Y; Wang X; Chen G; Shi A; Lu Y; Jia S; Kang X; Lu L
    Phytomedicine; 2020 Mar; 68():153186. PubMed ID: 32088353
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microrchidia family CW‑type zinc finger 2 promotes the proliferation, invasion, migration and epithelial‑mesenchymal transition of glioma by regulating PTEN/PI3K/AKT signaling via binding to N‑myc downstream regulated gene 1 promoter.
    Zhang J; Yang Y; Dong Y; Liu C
    Int J Mol Med; 2022 Feb; 49(2):. PubMed ID: 34913078
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and antineoplastic activity of novel hybrids of podophyllotoxin and indirubin against human leukaemia cancer cells as multifunctional anti-MDR agents.
    Wang J; Long L; Chen Y; Xu Y; Zhang L
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1817-1824. PubMed ID: 29678463
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of d-ring modified acid hydrazide derivatives of podophyllotoxin and their anticancer studies as Tubulin inhibiting agents.
    Nerella S; Kankala S; Paidakula S; Gavaji B
    Bioorg Chem; 2020 Jan; 94():103384. PubMed ID: 31776036
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Daidzin targets epithelial-to-mesenchymal transition process by attenuating manganese superoxide dismutase expression and PI3K/Akt/mTOR activation in tumor cells.
    Yang MH; Jung SH; Um JY; Kumar AP; Sethi G; Ahn KS
    Life Sci; 2022 Apr; 295():120395. PubMed ID: 35181309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A; Srinivasa Reddy T; Polepalli S; Shalini N; Reddy VG; Subba Rao AV; Jain N; Shankaraiah N
    Bioorg Med Chem; 2014 Oct; 22(19):5466-75. PubMed ID: 25131956
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of apoptotic DNA fragmentation mediated by mitochondrial pathway with caspase-3-dependent BID cleavage in human gastric cancer cells by a new nitroxyl spin-labeled derivative of podophyllotoxin.
    Yang YJ; Qi SN; Shi RY; Yao J; Wang LS; Yuan HQ; Jing YX
    Biomed Pharmacother; 2017 Jun; 90():131-138. PubMed ID: 28347917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.