These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 35662849)

  • 1. Sub-Lethal Concentrations of Graphene Oxide Trigger Acute-Phase Response and Impairment of Phase-I Xenobiotic Metabolism in Upcyte
    Romaldini A; Spanò R; Catalano F; Villa F; Poggi A; Sabella S
    Front Bioeng Biotechnol; 2022; 10():867728. PubMed ID: 35662849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human Multi-Lineage Liver Organoid Model Reveals Impairment of CYP3A4 Expression upon Repeated Exposure to Graphene Oxide.
    Romaldini A; Spanò R; Veronesi M; Grimaldi B; Bandiera T; Sabella S
    Cells; 2024 Sep; 13(18):. PubMed ID: 39329726
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.
    Schulz C; Kammerer S; Küpper JH
    Clin Hemorheol Microcirc; 2019; 73(1):249-260. PubMed ID: 31561354
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.
    Tolosa L; Gómez-Lechón MJ; López S; Guzmán C; Castell JV; Donato MT; Jover R
    Toxicol Sci; 2016 Jul; 152(1):214-29. PubMed ID: 27208088
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Generation & characterization of expandable human liver sinusoidal endothelial cells and their application to assess hepatotoxicity in an advanced in vitro liver model.
    Kaden T; Noerenberg A; Boldt J; Sagawe C; Johannssen T; Rennert K; Raasch M; Evenburg T
    Toxicology; 2023 Jan; 483():153374. PubMed ID: 36396002
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Generation of proliferating human hepatocytes using Upcyte® technology: characterisation and applications in induction and cytotoxicity assays.
    Burkard A; Dähn C; Heinz S; Zutavern A; Sonntag-Buck V; Maltman D; Przyborski S; Hewitt NJ; Braspenning J
    Xenobiotica; 2012 Oct; 42(10):939-56. PubMed ID: 22524704
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies.
    Ramachandran SD; Vivarès A; Klieber S; Hewitt NJ; Muenst B; Heinz S; Walles H; Braspenning J
    Pharmacol Res Perspect; 2015 Oct; 3(5):e00161. PubMed ID: 26516577
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
    Utkarsh D; Loretz C; Li AP
    Chem Biol Interact; 2016 Aug; 255():12-22. PubMed ID: 26718876
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cooperation of liver cells in health and disease.
    Kmieć Z
    Adv Anat Embryol Cell Biol; 2001; 161():III-XIII, 1-151. PubMed ID: 11729749
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells.
    Hu YH; Li DK; Quan ZY; Wang CY; Zhou M; Sun ZX
    J Ethnopharmacol; 2021 Apr; 270():113845. PubMed ID: 33485974
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results with Acetaminophen, Amiodarone, Cyclophosphamide, Ketoconazole, Nefazodone, and Troglitazone.
    Wei H; Li AP
    Drug Metab Dispos; 2022 Feb; 50(2):140-149. PubMed ID: 34750194
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro.
    Lübberstedt M; Müller-Vieira U; Mayer M; Biemel KM; Knöspel F; Knobeloch D; Nüssler AK; Gerlach JC; Zeilinger K
    J Pharmacol Toxicol Methods; 2011; 63(1):59-68. PubMed ID: 20460162
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oxidative-stress and long-term hepatotoxicity: comparative study in Upcyte human hepatocytes and hepaRG cells.
    Donato MT; Jiménez N; Pelechá M; Tolosa L
    Arch Toxicol; 2022 Apr; 96(4):1021-1037. PubMed ID: 35156134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gene Expression Profiling of 1α,25(OH)
    Pavek P; Dusek J; Smutny T; Lochman L; Kucera R; Skoda J; Smutna L; Kamaraj R; Soucek P; Vrzal R; Dvorak Z
    Mol Nutr Food Res; 2022 May; 66(9):e2200070. PubMed ID: 35184385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts.
    Donato MT; Lahoz A; Jiménez N; Pérez G; Serralta A; Mir J; Castell JV; Gómez-Lechón MJ
    Drug Metab Dispos; 2006 Sep; 34(9):1556-62. PubMed ID: 16763015
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism.
    Roque Bravo R; Carmo H; Valente MJ; Silva JP; Carvalho F; Bastos ML; Dias da Silva D
    Toxicology; 2021 Nov; 463():152988. PubMed ID: 34655687
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity.
    Qiao S; Feng S; Wu Z; He T; Ma C; Peng Z; Tian E; Pan G
    Drug Metab Dispos; 2021 Apr; 49(4):305-313. PubMed ID: 33526515
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening.
    Wang Z; Li W; Jing H; Ding M; Fu G; Yuan T; Huang W; Dai M; Tang D; Zeng M; Chen Y; Zhang H; Zhu X; Peng Y; Li Q; Yu WF; Yan HX; Zhai B
    Theranostics; 2019; 9(22):6690-6705. PubMed ID: 31588244
    [No Abstract]   [Full Text] [Related]  

  • 19. Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4.
    Zhang ZY; King BM; Pelletier RD; Wong YN
    Cancer Chemother Pharmacol; 2008 Sep; 62(4):707-16. PubMed ID: 18431572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Optimization of upcyte® human hepatocytes for the in vitro micronucleus assay.
    Nörenberg A; Heinz S; Scheller K; Hewitt NJ; Braspenning J; Ott M
    Mutat Res Genet Toxicol Environ Mutagen; 2013 Dec; 758(1-2):69-79. PubMed ID: 24140631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.