These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 35662849)

  • 21. Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge.
    Sanchez-Quant E; Richter ML; Colomé-Tatché M; Martinez-Jimenez CP
    Genome Biol; 2023 Oct; 24(1):234. PubMed ID: 37848949
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Evaluation of a Novel Renewable Hepatic Cell Model for Prediction of Clinical CYP3A4 Induction Using a Correlation-Based Relative Induction Score Approach.
    Zuo R; Li F; Parikh S; Cao L; Cooper KL; Hong Y; Liu J; Faris RA; Li D; Wang H
    Drug Metab Dispos; 2017 Feb; 45(2):198-207. PubMed ID: 28062541
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Low levels of graphene and graphene oxide inhibit cellular xenobiotic defense system mediated by efflux transporters.
    Liu S; Jiang W; Wu B; Yu J; Yu H; Zhang XX; Torres-Duarte C; Cherr GN
    Nanotoxicology; 2016; 10(5):597-606. PubMed ID: 26554512
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.
    Herzog N; Hansen M; Miethbauer S; Schmidtke KU; Anderer U; Lupp A; Sperling S; Seehofer D; Damm G; Scheibner K; Küpper JH
    Cell Biol Int; 2016 Mar; 40(3):341-53. PubMed ID: 26715207
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Kupffer cell-mediated differential down-regulation of cytochrome P450 metabolism in rat hepatocytes.
    Milosevic N; Schawalder H; Maier P
    Eur J Pharmacol; 1999 Feb; 368(1):75-87. PubMed ID: 10096772
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes.
    Yang LQ; Yu WF; Cao YF; Gong B; Chang Q; Yang GS
    World J Gastroenterol; 2003 Sep; 9(9):1959-62. PubMed ID: 12970884
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4.
    Danek PJ; Basińska-Ziobroń A; Wójcikowski J; Daniel WA
    Pharmacol Rep; 2021 Feb; 73(1):303-308. PubMed ID: 32888176
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Metabolism Comparative Cytotoxicity Assay (MCCA) and Cytotoxic Metabolic Pathway Identification Assay (CMPIA) with cryopreserved human hepatocytes for the evaluation of metabolism-based cytotoxicity in vitro: proof-of-concept study with aflatoxin B1.
    Li AP
    Chem Biol Interact; 2009 Apr; 179(1):4-8. PubMed ID: 18950609
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Metabolism and transporter-mediated drug-drug interactions of the endothelin-A receptor antagonist CI-1034.
    Sahi J; Sinz MW; Campbell S; Mireles R; Zheng X; Rose KA; Raeissi S; Hashim MF; Ye Y; de Morais SM; Black C; Tugnait M; Keller LH
    Chem Biol Interact; 2006 Feb; 159(2):156-68. PubMed ID: 16356485
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
    Rubiano A; Indapurkar A; Yokosawa R; Miedzik A; Rosenzweig B; Arefin A; Moulin CM; Dame K; Hartman N; Volpe DA; Matta MK; Hughes DJ; Strauss DG; Kostrzewski T; Ribeiro AJS
    Clin Transl Sci; 2021 May; 14(3):1049-1061. PubMed ID: 33382907
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The effect of graphene oxide on signalling of xenobiotic receptors involved in biotransformation.
    Ženata O; Vrzalová A; Bachleda P; Janečková J; Panáček A; Kvítek L; Vrzal R
    Chemosphere; 2020 Aug; 253():126753. PubMed ID: 32464781
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes.
    Rushmore TH; Kong AN
    Curr Drug Metab; 2002 Oct; 3(5):481-90. PubMed ID: 12369894
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Messenger RNA Expression of Albumin, Transferrin, Transthyretin, Asialoglycoprotein Receptor, Cytochrome P450 Isoform, Uptake Transporter, and Efflux Transporter Genes as a Function of Culture Duration in Prolonged Cultured Cryopreserved Human Hepatocytes as Collagen-Matrigel Sandwich Cultures: Evidence for Redifferentiation upon Prolonged Culturing.
    Yang Q; Li AP
    Drug Metab Dispos; 2021 Sep; 49(9):790-802. PubMed ID: 34135090
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: results with model toxicants aflatoxin B1, cyclophosphamide and tamoxifen.
    Li AP; Uzgare A; LaForge YS
    Chem Biol Interact; 2012 Jul; 199(1):1-8. PubMed ID: 22640811
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Cytotoxicity of three graphene-related materials in rainbow trout primary hepatocytes is not associated to cellular internalization.
    Kalman J; Torrent F; Navas JM
    Ecotoxicol Environ Saf; 2022 Feb; 231():113227. PubMed ID: 35077996
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Human hepatocytes as a tool for studying toxicity and drug metabolism.
    Gómez-Lechón MJ; Donato MT; Castell JV; Jover R
    Curr Drug Metab; 2003 Aug; 4(4):292-312. PubMed ID: 12871046
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Catalpol coordinately regulates phase I and II detoxification enzymes of Triptolide through CAR and NRF2 pathways to reduce Triptolide-induced hepatotoxicity.
    Fu L; Zhou L; Geng S; Li M; Lu W; Lu Y; Feng Z; Zhou X
    Biomed Pharmacother; 2020 Sep; 129():110379. PubMed ID: 32563148
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Study Liver Cytochrome P450 3A4 Inhibition and Hepatotoxicity Using DMSO-Differentiated HuH-7 Cells.
    Liu Y
    Methods Mol Biol; 2016; 1473():63-70. PubMed ID: 27518624
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes.
    Schaefer M; Morinaga G; Matsui A; Schänzle G; Bischoff D; Süssmuth RD
    Drug Metab Dispos; 2018 Feb; 46(2):166-177. PubMed ID: 29212823
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes and HepaRG cells.
    Klein M; Thomas M; Hofmann U; Seehofer D; Damm G; Zanger UM
    Drug Metab Dispos; 2015 Feb; 43(2):273-83. PubMed ID: 25480923
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.