BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 35668298)

  • 1. Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals.
    Sankar A; Mohammad F; Sundaramurthy AK; Wang H; Lerdrup M; Tatar T; Helin K
    Nat Genet; 2022 Jun; 54(6):754-760. PubMed ID: 35668298
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation.
    Schwämmle V; Sidoli S; Ruminowicz C; Wu X; Lee CF; Helin K; Jensen ON
    Mol Cell Proteomics; 2016 Aug; 15(8):2715-29. PubMed ID: 27302890
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity.
    Lavarone E; Barbieri CM; Pasini D
    Nat Commun; 2019 Apr; 10(1):1679. PubMed ID: 30976011
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.
    Tie F; Banerjee R; Stratton CA; Prasad-Sinha J; Stepanik V; Zlobin A; Diaz MO; Scacheri PC; Harte PJ
    Development; 2009 Sep; 136(18):3131-41. PubMed ID: 19700617
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation.
    Leatham-Jensen M; Uyehara CM; Strahl BD; Matera AG; Duronio RJ; McKay DJ
    PLoS Genet; 2019 Jan; 15(1):e1007932. PubMed ID: 30699116
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RBBP4 dysfunction reshapes the genomic landscape of H3K27 methylation and acetylation and disrupts gene expression.
    Mu W; Murcia NS; Smith KN; Menon DU; Yee D; Magnuson T
    G3 (Bethesda); 2022 May; 12(6):. PubMed ID: 35416979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2.
    Højfeldt JW; Laugesen A; Willumsen BM; Damhofer H; Hedehus L; Tvardovskiy A; Mohammad F; Jensen ON; Helin K
    Nat Struct Mol Biol; 2018 Mar; 25(3):225-232. PubMed ID: 29483650
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.
    Tie F; Banerjee R; Conrad PA; Scacheri PC; Harte PJ
    Mol Cell Biol; 2012 Jun; 32(12):2323-34. PubMed ID: 22493065
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IMITATION SWITCH is required for normal chromatin structure and gene repression in PRC2 target domains.
    Kamei M; Ameri AJ; Ferraro AR; Bar-Peled Y; Zhao F; Ethridge CL; Lail K; Amirebrahimi M; Lipzen A; Ng V; Grigoriev IV; Schmitz RJ; Liu Y; Lewis ZA
    Proc Natl Acad Sci U S A; 2021 Jan; 118(4):. PubMed ID: 33468665
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.
    Pasini D; Malatesta M; Jung HR; Walfridsson J; Willer A; Olsson L; Skotte J; Wutz A; Porse B; Jensen ON; Helin K
    Nucleic Acids Res; 2010 Aug; 38(15):4958-69. PubMed ID: 20385584
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone Deacetylase 1 (HDAC1) Negatively Regulates Thermogenic Program in Brown Adipocytes via Coordinated Regulation of Histone H3 Lysine 27 (H3K27) Deacetylation and Methylation.
    Li F; Wu R; Cui X; Zha L; Yu L; Shi H; Xue B
    J Biol Chem; 2016 Feb; 291(9):4523-36. PubMed ID: 26733201
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation.
    Yuan W; Wu T; Fu H; Dai C; Wu H; Liu N; Li X; Xu M; Zhang Z; Niu T; Han Z; Chai J; Zhou XJ; Gao S; Zhu B
    Science; 2012 Aug; 337(6097):971-5. PubMed ID: 22923582
    [TBL] [Abstract][Full Text] [Related]  

  • 13. H3K36 methylation antagonizes PRC2-mediated H3K27 methylation.
    Yuan W; Xu M; Huang C; Liu N; Chen S; Zhu B
    J Biol Chem; 2011 Mar; 286(10):7983-7989. PubMed ID: 21239496
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation.
    Healy E; Mucha M; Glancy E; Fitzpatrick DJ; Conway E; Neikes HK; Monger C; Van Mierlo G; Baltissen MP; Koseki Y; Vermeulen M; Koseki H; Bracken AP
    Mol Cell; 2019 Nov; 76(3):437-452.e6. PubMed ID: 31521505
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells.
    Wang Y; Long H; Yu J; Dong L; Wassef M; Zhuo B; Li X; Zhao J; Wang M; Liu C; Wen Z; Chang L; Chen P; Wang QF; Xu X; Margueron R; Li G
    BMC Biol; 2018 Sep; 16(1):107. PubMed ID: 30249243
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A histone mutant reproduces the phenotype caused by loss of histone-modifying factor Polycomb.
    Pengelly AR; Copur Ö; Jäckle H; Herzig A; Müller J
    Science; 2013 Feb; 339(6120):698-9. PubMed ID: 23393264
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36.
    Jung HR; Pasini D; Helin K; Jensen ON
    Mol Cell Proteomics; 2010 May; 9(5):838-50. PubMed ID: 20150217
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation.
    Mu W; Starmer J; Yee D; Magnuson T
    Epigenetics Chromatin; 2018 Dec; 11(1):71. PubMed ID: 30522506
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation.
    Laugesen A; Højfeldt JW; Helin K
    Mol Cell; 2019 Apr; 74(1):8-18. PubMed ID: 30951652
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity.
    Miller SA; Damle M; Kim J; Kingston RE
    Development; 2021 Apr; 148(7):. PubMed ID: 33688077
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.