BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 35696642)

  • 1. Hematopoietic Progenitor Kinase 1 in Tumor Immunology: A Medicinal Chemistry Perspective.
    Zhu Q; Chen N; Tian X; Zhou Y; You Q; Xu X
    J Med Chem; 2022 Jun; 65(12):8065-8090. PubMed ID: 35696642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Current strategies for targeting HPK1 in cancer and the barriers to preclinical progress.
    Chen H; Guan X; He C; Lu T; Lin X; Liao X
    Expert Opin Ther Targets; 2024 Apr; 28(4):237-250. PubMed ID: 38650383
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The development of small-molecule inhibitors targeting HPK1.
    Zhou L; Wang T; Zhang K; Zhang X; Jiang S
    Eur J Med Chem; 2022 Dec; 244():114819. PubMed ID: 36209628
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors.
    Wu F; Li H; An Q; Sun Y; Yu J; Cao W; Sun P; Diao X; Meng L; Xu S
    Eur J Med Chem; 2023 Jun; 254():115355. PubMed ID: 37062169
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The HPK1 Inhibitor A-745 Verifies the Potential of Modulating T Cell Kinase Signaling for Immunotherapy.
    Malchow S; Korepanova A; Panchal SC; McClure RA; Longenecker KL; Qiu W; Zhao H; Cheng M; Guo J; Klinge KL; Trusk P; Pratt SD; Li T; Kurnick MD; Duan L; Shoemaker AR; Gopalakrishnan SM; Warder SE; Shotwell JB; Lai A; Sun C; Osuma AT; Pappano WN
    ACS Chem Biol; 2022 Mar; 17(3):556-566. PubMed ID: 35188729
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function.
    Hernandez S; Qing J; Thibodeau RH; Du X; Park S; Lee HM; Xu M; Oh S; Navarro A; Roose-Girma M; Newman RJ; Warming S; Nannini M; Sampath D; Kim JM; Grogan JL; Mellman I
    Cell Rep; 2018 Oct; 25(1):80-94. PubMed ID: 30282040
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of immuno-oncology target HPK1 - a patent review (2016 to 2020).
    Linney ID; Kaila N
    Expert Opin Ther Pat; 2021 Oct; 31(10):893-910. PubMed ID: 33956554
    [No Abstract]   [Full Text] [Related]  

  • 8. Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.
    Arnold R; Patzak IM; Neuhaus B; Vancauwenbergh S; Veillette A; Van Lint J; Kiefer F
    Mol Cell Biol; 2005 Mar; 25(6):2364-83. PubMed ID: 15743830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors.
    Qiu X; Liu R; Ling H; Zhou Y; Ren X; Zhou F; Zhang J; Huang W; Wang Z; Ding K
    Eur J Med Chem; 2024 Apr; 269():116310. PubMed ID: 38479166
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of diaminotriazine carboxamides as potent inhibitors of hematopoetic progenitor kinase 1.
    Zhou L; Ye X; Wang K; Shen H; Wang T; Zhang X; Jiang S; Xiao Y; Zhang K
    Bioorg Chem; 2023 Sep; 138():106682. PubMed ID: 37339563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation.
    Alzabin S; Bhardwaj N; Kiefer F; Sawasdikosol S; Burakoff S
    J Immunol; 2009 May; 182(10):6187-94. PubMed ID: 19414772
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling.
    Ling P; Meyer CF; Redmond LP; Shui JW; Davis B; Rich RR; Hu MC; Wange RL; Tan TH
    J Biol Chem; 2001 Jun; 276(22):18908-14. PubMed ID: 11279207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Down-regulation of B cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and ubiquitination of activated B cell linker protein (BLNK).
    Wang X; Li JP; Kuo HK; Chiu LL; Dement GA; Lan JL; Chen DY; Yang CY; Hu H; Tan TH
    J Biol Chem; 2012 Mar; 287(14):11037-48. PubMed ID: 22334673
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.
    Zhou G; Boomer JS; Tan TH
    J Biol Chem; 2004 Nov; 279(47):49551-61. PubMed ID: 15364934
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HPK1 as a novel target for cancer immunotherapy.
    Sawasdikosol S; Zha R; Yang B; Burakoff S
    Immunol Res; 2012 Dec; 54(1-3):262-5. PubMed ID: 22477524
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel hematopoietic progenitor kinase 1 inhibitor KHK-6 enhances T-cell activation.
    Ahn MJ; Kim EH; Choi Y; Chae CH; Kim P; Kim SH
    PLoS One; 2024; 19(6):e0305261. PubMed ID: 38923962
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors.
    Zhang J; Li Y; Tang H; Zhou Q; Tong L; Ding J; Xie H; Xiong B; Liu T
    Bioorg Chem; 2023 Nov; 140():106811. PubMed ID: 37659145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors.
    Shi H; Tang H; Li Y; Chen D; Liu T; Chen Y; Wang X; Chen L; Wang Y; Xie H; Xiong B
    Eur J Med Chem; 2023 Feb; 248():115064. PubMed ID: 36621137
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological inhibition of hematopoietic progenitor kinase 1 positively regulates T-cell function.
    Wang Y; Zhang K; Georgiev P; Wells S; Xu H; Lacey BM; Xu Z; Laskey J; Mcleod R; Methot JL; Bittinger M; Pasternak A; Ranganath S
    PLoS One; 2020; 15(12):e0243145. PubMed ID: 33270695
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interactions between hematopoietic progenitor kinase 1 and its adaptor proteins (Review).
    Zhang Q; Ding S; Zhang H
    Mol Med Rep; 2017 Nov; 16(5):6472-6482. PubMed ID: 28901492
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.