185 related articles for article (PubMed ID: 35699162)
1. Impact of Fluoroalkyl Substituents on the Physicochemical Properties of Saturated Heterocyclic Amines.
Melnykov KP; Tavlui O; Skreminskiy A; Kuchkovska YO; Grygorenko OO
Chemistry; 2022 Oct; 28(55):e202201601. PubMed ID: 35699162
[TBL] [Abstract][Full Text] [Related]
2. Mono- and Difluorinated Saturated Heterocyclic Amines for Drug Discovery: Systematic Study of Their Physicochemical Properties.
Melnykov KP; Nazar K; Smyrnov O; Skreminskyi A; Pavlenko S; Klymenko-Ulianov O; Shishkina S; Volochnyuk DM; Grygorenko OO
Chemistry; 2023 Aug; 29(47):e202301383. PubMed ID: 37318940
[TBL] [Abstract][Full Text] [Related]
3. Effect of gem-Difluorination on the Key Physicochemical Properties Relevant to Medicinal Chemistry: The Case of Functionalized Cycloalkanes.
Holovach S; Melnykov KP; Skreminskiy A; Herasymchuk M; Tavlui O; Aloshyn D; Borysko P; Rozhenko AB; Ryabukhin SV; Volochnyuk DM; Grygorenko OO
Chemistry; 2022 Apr; 28(19):e202200331. PubMed ID: 35147261
[TBL] [Abstract][Full Text] [Related]
4. Fluorinated Cycloalkyl Building Blocks for Drug Discovery.
Grygorenko OO; Melnykov KP; Holovach S; Demchuk O
ChemMedChem; 2022 Nov; 17(21):e202200365. PubMed ID: 36031924
[TBL] [Abstract][Full Text] [Related]
5. Aromatic and amine substituent effects on the apparent lipophilicities of N-[(2-pyrrolidinyl)methyl]-substituted benzamides.
Schmidt DE; Votaw JR; Kessler RM; de Paulis T
J Pharm Sci; 1994 Mar; 83(3):305-15. PubMed ID: 8207673
[TBL] [Abstract][Full Text] [Related]
6. Fluoroalkyl Amino Reagents (FARs): A General Approach towards the Synthesis of Heterocyclic Compounds Bearing Emergent Fluorinated Substituents.
Commare B; Schmitt E; Aribi F; Panossian A; Vors JP; Pazenok S; Leroux FR
Molecules; 2017 Jun; 22(6):. PubMed ID: 28604633
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of fluorinated chiral amines using N-tert-butylsulfinyl imines.
Liu J; Hu J
Future Med Chem; 2009 Aug; 1(5):875-88. PubMed ID: 21426086
[TBL] [Abstract][Full Text] [Related]
8. Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs.
Troup RI; Jeffries B; Saudain RE; Georgiou E; Fish J; Scott JS; Chiarparin E; Fallan C; Linclau B
J Org Chem; 2021 Jan; 86(2):1882-1900. PubMed ID: 33400526
[TBL] [Abstract][Full Text] [Related]
9. Practical synthesis of fluorine-containing α- and β-amino acids: recipes from Kiev, Ukraine.
Kukhar VP; Sorochinsky AE; Soloshonok VA
Future Med Chem; 2009 Aug; 1(5):793-819. PubMed ID: 21426081
[TBL] [Abstract][Full Text] [Related]
10. Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug Discovery.
Huchet QA; Kuhn B; Wagner B; Kratochwil NA; Fischer H; Kansy M; Zimmerli D; Carreira EM; Müller K
J Med Chem; 2015 Nov; 58(22):9041-60. PubMed ID: 26523333
[TBL] [Abstract][Full Text] [Related]
11. Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs.
Jeffries B; Wang Z; Felstead HR; Le Questel JY; Scott JS; Chiarparin E; Graton J; Linclau B
J Med Chem; 2020 Feb; 63(3):1002-1031. PubMed ID: 31894985
[TBL] [Abstract][Full Text] [Related]
12. Fluorination methods in drug discovery.
Yerien DE; Bonesi S; Postigo A
Org Biomol Chem; 2016 Sep; 14(36):8398-427. PubMed ID: 27506398
[TBL] [Abstract][Full Text] [Related]
13. α-Fluorination of carbonyls with nucleophilic fluorine.
Adler P; Teskey CJ; Kaiser D; Holy M; Sitte HH; Maulide N
Nat Chem; 2019 Apr; 11(4):329-334. PubMed ID: 30833720
[TBL] [Abstract][Full Text] [Related]
14. Effect of Partially Fluorinated N-Alkyl-Substituted Piperidine-2-carboxamides on Pharmacologically Relevant Properties.
Vorberg R; Trapp N; Zimmerli D; Wagner B; Fischer H; Kratochwil NA; Kansy M; Carreira EM; Müller K
ChemMedChem; 2016 Oct; 11(19):2216-2239. PubMed ID: 27629993
[TBL] [Abstract][Full Text] [Related]
15. Modular synthesis of cyclic β-difluoroamines.
Charlesworth NG; Arunprasath D; Graham MA; Argent SP; Datsenko OP; Mykhailiuk PK; Denton RM
Chem Commun (Camb); 2024 Jun; ():. PubMed ID: 38896427
[TBL] [Abstract][Full Text] [Related]
16. Fluorine in medicinal chemistry.
Böhm HJ; Banner D; Bendels S; Kansy M; Kuhn B; Müller K; Obst-Sander U; Stahl M
Chembiochem; 2004 May; 5(5):637-43. PubMed ID: 15122635
[TBL] [Abstract][Full Text] [Related]
17. Fluorinated scaffolds for antimalarial drug discovery.
Upadhyay C; Chaudhary M; De Oliveira RN; Borbas A; Kempaiah P; Singh P; Rathi B
Expert Opin Drug Discov; 2020 Jun; 15(6):705-718. PubMed ID: 32202162
[TBL] [Abstract][Full Text] [Related]
18. Recent advances in the synthesis of fluorinated amino acids and peptides.
Zhou M; Feng Z; Zhang X
Chem Commun (Camb); 2023 Feb; 59(11):1434-1448. PubMed ID: 36651307
[TBL] [Abstract][Full Text] [Related]
19. Developments in fluorocyclization methodologies.
Wilkinson SC; Salmon R; Gouverneur V
Future Med Chem; 2009 Aug; 1(5):847-63. PubMed ID: 21426084
[TBL] [Abstract][Full Text] [Related]
20. Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design.
Meanwell NA
J Med Chem; 2018 Jul; 61(14):5822-5880. PubMed ID: 29400967
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
