BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 35703003)

  • 21. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.
    Li YR; Liu FF; Liu WB; Zhang YF; Tian XY; Fu XJ; Xu Y; Song J; Zhang SY
    Biochem Pharmacol; 2022 Jul; 201():115070. PubMed ID: 35526597
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design, synthesis and evaluation of calix[4]arene-based carbonyl amide derivatives with antitumor activities.
    An L; Wang C; Zheng YG; Liu JD; Huang TH
    Eur J Med Chem; 2021 Jan; 210():112984. PubMed ID: 33183867
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
    Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design and synthesis of 6,7-methylenedioxy-4-substituted phenylquinolin-2(1H)-one derivatives as novel anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase.
    Chen YF; Lin YC; Huang PK; Chan HC; Kuo SC; Lee KH; Huang LJ
    Bioorg Med Chem; 2013 Sep; 21(17):5064-75. PubMed ID: 23867385
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery of novel heteroarylmethylcarbamodithioates as potent anticancer agents: Synthesis, structure-activity relationship analysis and biological evaluation.
    Li YB; Yan X; Li RD; Liu P; Sun SQ; Wang X; Cui JR; Zhou DM; Ge ZM; Li RT
    Eur J Med Chem; 2016 Apr; 112():217-230. PubMed ID: 26900655
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis of Amide and Ester Derivatives of Cinnamic Acid and Its Analogs: Evaluation of Their Free Radical Scavenging and Monoamine Oxidase and Cholinesterase Inhibitory Activities.
    Takao K; Toda K; Saito T; Sugita Y
    Chem Pharm Bull (Tokyo); 2017; 65(11):1020-1027. PubMed ID: 29093288
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, Synthesis and Cytotoxic Activity Evaluation of Newly Synthesized Amides-Based TMP Moiety as Potential Anticancer Agents over HepG2 Cells.
    Al-Warhi T; Aldhahrani A; Althobaiti F; Fayad E; Abu Ali OA; Albogami S; Abu Almaaty AH; Khedr AIM; Bukhari SNA; Zaki I
    Molecules; 2022 Jun; 27(12):. PubMed ID: 35745081
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Novel 4,5-dihydrospiro[benzo[c]azepine-1,1'-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation.
    Li S; Li XY; Zhang TJ; Zhu J; Liu KL; Wang DP; Meng FH
    Bioorg Chem; 2021 Jun; 111():104840. PubMed ID: 33780687
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Novel small molecules as apoptosis inducers: synthesis, preliminary structure-activity relationships, and in vitro biological evaluation.
    Zhao L; Li X; Zhang L; Ye T; Zhu Y; Wei Y; Yang S; Yu L
    Bioorg Med Chem Lett; 2013 Apr; 23(8):2293-7. PubMed ID: 23489624
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design, synthesis and biological evaluation of novel 3-alkylsulfanyl-4-amino-1,2,4-triazole derivatives.
    Zhao PL; Chen P; Li Q; Hu MJ; Diao PC; Pan ES; You WW
    Bioorg Med Chem Lett; 2016 Aug; 26(15):3679-83. PubMed ID: 27287368
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cytotoxicity, Pro-apoptotic Activity and in silico Studies of Dithiocarbamates and their Structure Based Design and SAR Studies.
    Hamdani SS; Khan BA; Hameed S; Rashid F; Zaib S; Ahmad K; Mughal EU; Iqbal J
    Med Chem; 2019; 15(8):892-902. PubMed ID: 30747078
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities.
    Su Y; Li R; Ning X; Lin Z; Zhao X; Zhou J; Liu J; Jin Y; Yin Y
    Eur J Med Chem; 2019 Sep; 177():32-46. PubMed ID: 31129452
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery of novel dihydroartemisinin-cinnamic hybrids inducing lung cancer cells apoptosis via inhibition of Akt/Bad signal pathway.
    Hu Y; Wang Y; Li N; Chen L; Sun J
    Bioorg Chem; 2021 Jun; 111():104903. PubMed ID: 33894433
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis, in vitro and in vivo antitumor activity of scopoletin-cinnamic acid hybrids.
    Li L; Zhao P; Hu J; Liu J; Liu Y; Wang Z; Xia Y; Dai Y; Chen L
    Eur J Med Chem; 2015 Mar; 93():300-7. PubMed ID: 25703298
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Discovery of 1,2,4-triazine dithiocarbamate derivatives as NEDDylation agonists to inhibit gastric cancers.
    Song J; Liu Y; Yuan XY; Liu WB; Li YR; Yu GX; Tian XY; Zhang YB; Fu XJ; Zhang SY
    Eur J Med Chem; 2021 Dec; 225():113801. PubMed ID: 34455358
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design, synthesis, in vitro antiproliferative evaluation and GSK-3β kinase inhibition of a new series of pyrimidin-4-one based amide conjugates.
    Khan I; Tantray MA; Hamid H; Sarwar Alam M; Sharma K; Kesharwani P
    Bioorg Chem; 2022 Feb; 119():105512. PubMed ID: 34861627
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis, and preliminary biological evaluation of chrysin amino acid derivatives that induce apoptosis and suppress cell migration.
    Liu YM; Li Y; Xiao J; Zhang QZ; Song JX
    J Asian Nat Prod Res; 2020 Jun; 22(6):547-561. PubMed ID: 30938545
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, Synthesis and Bioactivity Evaluation of Novel Chalcone Derivatives Possessing Tryptophan Moiety with Dual Activities of Anti-Cancer and Partially Restoring the Proliferation of Normal Kidney Cells Pre-Treated with Cisplatin.
    He M; Yu M; Li C; Meng X; Su J; Zhu Y; Yao R
    Anticancer Agents Med Chem; 2022; 22(10):1945-1961. PubMed ID: 34674626
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and biological evaluation of novel steroidal pyrazole amides as highly potent anticancer agents.
    Huo H; Jiang W; Sun F; Li J; Shi B
    Steroids; 2021 Dec; 176():108931. PubMed ID: 34655595
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.