BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

398 related articles for article (PubMed ID: 35705809)

  • 1. cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers.
    Hong C; Schubert M; Tijhuis AE; Requesens M; Roorda M; van den Brink A; Ruiz LA; Bakker PL; van der Sluis T; Pieters W; Chen M; Wardenaar R; van der Vegt B; Spierings DCJ; de Bruyn M; van Vugt MATM; Foijer F
    Nature; 2022 Jul; 607(7918):366-373. PubMed ID: 35705809
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients.
    Vasiyani H; Mane M; Rana K; Shinde A; Roy M; Singh J; Gohel D; Currim F; Srivastava R; Singh R
    Apoptosis; 2022 Dec; 27(11-12):961-978. PubMed ID: 36018392
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IL6 Signaling Enables Survival of Chromosomally Instable Cancer Cells.
    Cancer Discov; 2022 Aug; 12(8):1836. PubMed ID: 35748594
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cGAS/STING/TBK1/IRF3 innate immunity pathway maintains chromosomal stability through regulation of p21 levels.
    Basit A; Cho MG; Kim EY; Kwon D; Kang SJ; Lee JH
    Exp Mol Med; 2020 Apr; 52(4):643-657. PubMed ID: 32284536
    [TBL] [Abstract][Full Text] [Related]  

  • 5. cGAS-STING signalling in cancer: striking a balance with chromosomal instability.
    Beernaert B; Parkes EE
    Biochem Soc Trans; 2023 Apr; 51(2):539-555. PubMed ID: 36876871
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability.
    Hong C; Tijhuis AE; Foijer F
    Cells; 2019 Oct; 8(10):. PubMed ID: 31658669
    [TBL] [Abstract][Full Text] [Related]  

  • 7. cGAS-STING and the deadly CIN: how chronic inflammation represents a therapeutic vulnerability in chromosomally unstable cancers.
    Bakhoum SF
    Trends Cancer; 2022 Oct; 8(10):788-789. PubMed ID: 35915014
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-cell-autonomous cancer progression from chromosomal instability.
    Li J; Hubisz MJ; Earlie EM; Duran MA; Hong C; Varela AA; Lettera E; Deyell M; Tavora B; Havel JJ; Phyu SM; Amin AD; Budre K; Kamiya E; Cavallo JA; Garris C; Powell S; Reis-Filho JS; Wen H; Bettigole S; Khan AJ; Izar B; Parkes EE; Laughney AM; Bakhoum SF
    Nature; 2023 Aug; 620(7976):1080-1088. PubMed ID: 37612508
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS-STING signalling.
    Wheeler OPG; Unterholzner L
    Essays Biochem; 2023 Sep; 67(6):905-918. PubMed ID: 37534795
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Eribulin induces micronuclei and enhances the nuclear localization of cGAS in triple-negative breast cancer cells.
    Yamada H; Takada M; Ghone D; Yu M; Nagashima T; Fujimoto H; Sakakibara J; Hasegawa Y; Takao S; Yamada A; Narui K; Ishikawa T; Suzuki A; Otsuka M
    Sci Rep; 2024 Jun; 14(1):14146. PubMed ID: 38898119
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial DNA drives noncanonical inflammation activation via cGAS-STING signaling pathway in retinal microvascular endothelial cells.
    Guo Y; Gu R; Gan D; Hu F; Li G; Xu G
    Cell Commun Signal; 2020 Oct; 18(1):172. PubMed ID: 33115500
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor effects of interleukin-6 (IL-6)/interleukin-6 receptor (IL-6R) signaling pathway inhibition in clear cell carcinoma of the ovary.
    Yanaihara N; Hirata Y; Yamaguchi N; Noguchi Y; Saito M; Nagata C; Takakura S; Yamada K; Okamoto A
    Mol Carcinog; 2016 May; 55(5):832-41. PubMed ID: 25856562
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chromosomal instability drives metastasis through a cytosolic DNA response.
    Bakhoum SF; Ngo B; Laughney AM; Cavallo JA; Murphy CJ; Ly P; Shah P; Sriram RK; Watkins TBK; Taunk NK; Duran M; Pauli C; Shaw C; Chadalavada K; Rajasekhar VK; Genovese G; Venkatesan S; Birkbak NJ; McGranahan N; Lundquist M; LaPlant Q; Healey JH; Elemento O; Chung CH; Lee NY; Imielenski M; Nanjangud G; Pe'er D; Cleveland DW; Powell SN; Lammerding J; Swanton C; Cantley LC
    Nature; 2018 Jan; 553(7689):467-472. PubMed ID: 29342134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular mechanisms and cellular functions of cGAS-STING signalling.
    Hopfner KP; Hornung V
    Nat Rev Mol Cell Biol; 2020 Sep; 21(9):501-521. PubMed ID: 32424334
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple-negative breast cancer.
    Alraouji NN; Al-Mohanna FH; Ghebeh H; Arafah M; Almeer R; Al-Tweigeri T; Aboussekhra A
    Mol Carcinog; 2020 Sep; 59(9):1041-1051. PubMed ID: 32537818
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relationship between the cGAS-STING and NF-κB pathways-role in neurotoxicity.
    Zhong S; Zhou Q; Yang J; Zhang Z; Zhang X; Liu J; Chang X; Wang H
    Biomed Pharmacother; 2024 Jun; 175():116698. PubMed ID: 38713946
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer.
    Sokač M; Ahrenfeldt J; Litchfield K; Watkins TBK; Knudsen M; Dyrskjøt L; Jakobsen MR; Birkbak NJ
    Cancer Res Commun; 2022 Aug; 2(8):762-771. PubMed ID: 36923311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer.
    Weng YS; Tseng HY; Chen YA; Shen PC; Al Haq AT; Chen LM; Tung YC; Hsu HL
    Mol Cancer; 2019 Mar; 18(1):42. PubMed ID: 30885232
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling.
    Epstein Shochet G; Brook E; Bardenstein-Wald B; Shitrit D
    Respir Res; 2020 Feb; 21(1):56. PubMed ID: 32070329
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cancer cell-autonomous cGAS-STING response confers drug resistance.
    Lv QM; Lei HM; Wang SY; Zhang KR; Tang YB; Shen Y; Lu LM; Chen HZ; Zhu L
    Cell Chem Biol; 2023 Jun; 30(6):591-605.e4. PubMed ID: 37263275
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.