265 related articles for article (PubMed ID: 35717259)
1. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions.
Zhao P; Xu Y; Jiang LL; Fan X; Ku Z; Li L; Liu X; Deng M; Arase H; Zhu JJ; Huang TY; Zhao Y; Zhang C; Xu H; Tong Q; Zhang N; An Z
Mol Neurodegener; 2022 Jun; 17(1):44. PubMed ID: 35717259
[TBL] [Abstract][Full Text] [Related]
2. A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease.
Zhao P; Xu Y; Jiang L; Fan X; Li L; Li X; Arase H; Zhao Y; Cao W; Zheng H; Xu H; Tong Q; Zhang N; An Z
Sci Transl Med; 2022 Sep; 14(661):eabq0095. PubMed ID: 36070367
[TBL] [Abstract][Full Text] [Related]
3. Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the
Shi Q; Chang C; Saliba A; Bhat MA
J Neurosci; 2022 Jul; 42(27):5294-5313. PubMed ID: 35672148
[TBL] [Abstract][Full Text] [Related]
4. Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease.
Wang X; Xie Y; Fan X; Wu X; Wang D; Zhu L
Alzheimers Res Ther; 2024 Jun; 16(1):121. PubMed ID: 38831312
[TBL] [Abstract][Full Text] [Related]
5. Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
Ellwanger DC; Wang S; Brioschi S; Shao Z; Green L; Case R; Yoo D; Weishuhn D; Rathanaswami P; Bradley J; Rao S; Cha D; Luan P; Sambashivan S; Gilfillan S; Hasson SA; Foltz IN; van Lookeren Campagne M; Colonna M
Proc Natl Acad Sci U S A; 2021 Jan; 118(3):. PubMed ID: 33446504
[TBL] [Abstract][Full Text] [Related]
6. TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia.
Jairaman A; McQuade A; Granzotto A; Kang YJ; Chadarevian JP; Gandhi S; Parker I; Smith I; Cho H; Sensi SL; Othy S; Blurton-Jones M; Cahalan MD
Elife; 2022 Feb; 11():. PubMed ID: 35191835
[TBL] [Abstract][Full Text] [Related]
7. Reduced TREM2 activation in microglia of patients with Alzheimer's disease.
Okuzono Y; Sakuma H; Miyakawa S; Ifuku M; Lee J; Das D; Banerjee A; Zhao Y; Yamamoto K; Ando T; Sato S
FEBS Open Bio; 2021 Nov; 11(11):3063-3080. PubMed ID: 34523252
[TBL] [Abstract][Full Text] [Related]
8. Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.
Delizannis AT; Nonneman A; Tsering W; De Bondt A; Van den Wyngaert I; Zhang B; Meymand E; Olufemi MF; Koivula P; Maimaiti S; Trojanowski JQ; Lee VM; Brunden KR
Acta Neuropathol Commun; 2021 Sep; 9(1):150. PubMed ID: 34503586
[TBL] [Abstract][Full Text] [Related]
9. SHIP inhibition mediates select TREM2-induced microglial functions.
Ramakrishnan GS; Berry WL; Pacherille A; Kerr WG; Chisholm JD; Pedicone C; Humphrey MB
Mol Immunol; 2024 Jun; 170():35-45. PubMed ID: 38613944
[TBL] [Abstract][Full Text] [Related]
10. A Trem2
Tran KM; Kawauchi S; Kramár EA; Rezaie N; Liang HY; Sakr JS; Gomez-Arboledas A; Arreola MA; Cunha CD; Phan J; Wang S; Collins S; Walker A; Shi KX; Neumann J; Filimban G; Shi Z; Milinkeviciute G; Javonillo DI; Tran K; Gantuz M; Forner S; Swarup V; Tenner AJ; LaFerla FM; Wood MA; Mortazavi A; MacGregor GR; Green KN
Mol Neurodegener; 2023 Feb; 18(1):12. PubMed ID: 36803190
[TBL] [Abstract][Full Text] [Related]
11. Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss.
Popescu AS; Butler CA; Allendorf DH; Piers TM; Mallach A; Roewe J; Reinhardt P; Cinti A; Redaelli L; Boudesco C; Pradier L; Pocock JM; Thornton P; Brown GC
Glia; 2023 Apr; 71(4):974-990. PubMed ID: 36480007
[TBL] [Abstract][Full Text] [Related]
12. Curcumin restores innate immune Alzheimer's disease risk gene expression to ameliorate Alzheimer pathogenesis.
Teter B; Morihara T; Lim GP; Chu T; Jones MR; Zuo X; Paul RM; Frautschy SA; Cole GM
Neurobiol Dis; 2019 Jul; 127():432-448. PubMed ID: 30951849
[TBL] [Abstract][Full Text] [Related]
13. Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition.
Price BR; Sudduth TL; Weekman EM; Johnson S; Hawthorne D; Woolums A; Wilcock DM
J Neuroinflammation; 2020 Aug; 17(1):238. PubMed ID: 32795308
[TBL] [Abstract][Full Text] [Related]
14. TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Hall-Roberts H; Agarwal D; Obst J; Smith TB; Monzón-Sandoval J; Di Daniel E; Webber C; James WS; Mead E; Davis JB; Cowley SA
Alzheimers Res Ther; 2020 Nov; 12(1):151. PubMed ID: 33198789
[TBL] [Abstract][Full Text] [Related]
15. iPSC-derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss.
Penney J; Ralvenius WT; Loon A; Cerit O; Dileep V; Milo B; Pao PC; Woolf H; Tsai LH
Glia; 2024 Feb; 72(2):452-469. PubMed ID: 37969043
[TBL] [Abstract][Full Text] [Related]
16. Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.
Vandermeulen L; Geric I; Fumagalli L; Kreir M; Lu A; Nonneman A; Premereur J; Wolfs L; Policarpo R; Fattorelli N; De Bondt A; Van Den Wyngaert I; Asselbergh B; Fiers M; De Strooper B; d'Ydewalle C; Mancuso R
Mol Neurodegener; 2024 Apr; 19(1):37. PubMed ID: 38654375
[TBL] [Abstract][Full Text] [Related]
17. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Parhizkar S; Arzberger T; Brendel M; Kleinberger G; Deussing M; Focke C; Nuscher B; Xiong M; Ghasemigharagoz A; Katzmarski N; Krasemann S; Lichtenthaler SF; Müller SA; Colombo A; Monasor LS; Tahirovic S; Herms J; Willem M; Pettkus N; Butovsky O; Bartenstein P; Edbauer D; Rominger A; Ertürk A; Grathwohl SA; Neher JJ; Holtzman DM; Meyer-Luehmann M; Haass C
Nat Neurosci; 2019 Feb; 22(2):191-204. PubMed ID: 30617257
[TBL] [Abstract][Full Text] [Related]
18. TREM2-induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology.
Fracassi A; Marcatti M; Tumurbaatar B; Woltjer R; Moreno S; Taglialatela G
Brain Pathol; 2023 Jan; 33(1):e13108. PubMed ID: 35816404
[TBL] [Abstract][Full Text] [Related]
19. Acute
Schoch KM; Ezerskiy LA; Morhaus MM; Bannon RN; Sauerbeck AD; Shabsovich M; Jafar-Nejad P; Rigo F; Miller TM
Proc Natl Acad Sci U S A; 2021 Jul; 118(27):. PubMed ID: 34187891
[TBL] [Abstract][Full Text] [Related]
20. Microglial TREM2 at the Intersection of Brain Aging and Alzheimer's Disease.
Qu W; Li L
Neuroscientist; 2023 Jun; 29(3):302-316. PubMed ID: 34470515
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
