BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 35717559)

  • 1. Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types.
    Paes D; Hermans S; van den Hove D; Vanmierlo T; Prickaerts J; Carlier A
    Biophys J; 2022 Jul; 121(14):2693-2711. PubMed ID: 35717559
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of ERK2 docking and phosphorylation of PDE4 cAMP phosphodiesterase isoforms in mediating cross-talk between the cAMP and ERK signalling pathways.
    Houslay MD; Baillie GS
    Biochem Soc Trans; 2003 Dec; 31(Pt 6):1186-90. PubMed ID: 14641023
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant.
    Erdogan S; Houslay MD
    Biochem J; 1997 Jan; 321 ( Pt 1)(Pt 1):165-75. PubMed ID: 9003416
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia-induced remodelling of PDE4 isoform expression and cAMP handling in human pulmonary artery smooth muscle cells.
    Millen J; MacLean MR; Houslay MD
    Eur J Cell Biol; 2006 Jul; 85(7):679-91. PubMed ID: 16458997
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Vascular smooth muscle cell phosphodiesterase (PDE) 3 and PDE4 activities and levels are regulated by cyclic AMP in vivo.
    Tilley DG; Maurice DH
    Mol Pharmacol; 2002 Sep; 62(3):497-506. PubMed ID: 12181425
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).
    Cheung YF; Kan Z; Garrett-Engele P; Gall I; Murdoch H; Baillie GS; Camargo LM; Johnson JM; Houslay MD; Castle JC
    J Pharmacol Exp Ther; 2007 Aug; 322(2):600-9. PubMed ID: 17519386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of cyclic AMP in rat pulmonary microvascular endothelial cells by rolipram-sensitive cyclic AMP phosphodiesterase (PDE4).
    Thompson WJ; Ashikaga T; Kelly JJ; Liu L; Zhu B; Vemavarapu L; Strada SJ
    Biochem Pharmacol; 2002 Feb; 63(4):797-807. PubMed ID: 11992650
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process.
    Terry R; Cheung YF; Praestegaard M; Baillie GS; Huston E; Gall I; Adams DR; Houslay MD
    Cell Signal; 2003 Oct; 15(10):955-71. PubMed ID: 12873709
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.
    Houslay MD; Adams DR
    Biochem J; 2003 Feb; 370(Pt 1):1-18. PubMed ID: 12444918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.
    Houslay MD; Baillie GS; Maurice DH
    Circ Res; 2007 Apr; 100(7):950-66. PubMed ID: 17431197
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
    Omar F; Findlay JE; Carfray G; Allcock RW; Jiang Z; Moore C; Muir AL; Lannoy M; Fertig BA; Mai D; Day JP; Bolger G; Baillie GS; Schwiebert E; Klussmann E; Pyne NJ; Ong ACM; Bowers K; Adam JM; Adams DR; Houslay MD; Henderson DJP
    Proc Natl Acad Sci U S A; 2019 Jul; 116(27):13320-13329. PubMed ID: 31209056
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PDE4 Phosphodiesterases in Cardiovascular Diseases: Key Pathophysiological Players and Potential Therapeutic Targets.
    Puertas-Umbert L; Alonso J; Hove-Madsen L; Martínez-González J; Rodríguez C
    Int J Mol Sci; 2023 Nov; 24(23):. PubMed ID: 38069339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.
    Murdoch H; Mackie S; Collins DM; Hill EV; Bolger GB; Klussmann E; Porteous DJ; Millar JK; Houslay MD
    J Neurosci; 2007 Aug; 27(35):9513-24. PubMed ID: 17728464
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).
    MacKenzie SJ; Baillie GS; McPhee I; MacKenzie C; Seamons R; McSorley T; Millen J; Beard MB; van Heeke G; Houslay MD
    Br J Pharmacol; 2002 Jun; 136(3):421-33. PubMed ID: 12023945
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.
    Shepherd MC; Baillie GS; Stirling DI; Houslay MD
    Br J Pharmacol; 2004 May; 142(2):339-51. PubMed ID: 15066910
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory.
    Havekes R; Park AJ; Tolentino RE; Bruinenberg VM; Tudor JC; Lee Y; Hansen RT; Guercio LA; Linton E; Neves-Zaph SR; Meerlo P; Baillie GS; Houslay MD; Abel T
    J Neurosci; 2016 Aug; 36(34):8936-46. PubMed ID: 27559174
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphodiesterase 4 inhibition synergizes with relaxin signaling to promote decidualization of human endometrial stromal cells.
    Bartsch O; Bartlick B; Ivell R
    J Clin Endocrinol Metab; 2004 Jan; 89(1):324-34. PubMed ID: 14715868
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitotic activation of the DISC1-inducible cyclic AMP phosphodiesterase-4D9 (PDE4D9), through multi-site phosphorylation, influences cell cycle progression.
    Sheppard CL; Lee LC; Hill EV; Henderson DJ; Anthony DF; Houslay DM; Yalla KC; Cairns LS; Dunlop AJ; Baillie GS; Huston E; Houslay MD
    Cell Signal; 2014 Sep; 26(9):1958-74. PubMed ID: 24815749
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling.
    Lynch MJ; Hill EV; Houslay MD
    Curr Top Dev Biol; 2006; 75():225-59. PubMed ID: 16984814
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of substrate specificity determinants in human cAMP-specific phosphodiesterase 4A by single-point mutagenesis.
    Richter W; Unciuleac L; Hermsdorf T; Kronbach T; Dettmer D
    Cell Signal; 2001 Mar; 13(3):159-67. PubMed ID: 11282454
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.