BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 35717870)

  • 41. Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors.
    Duan H; Zhang J; Gui R; Lu Y; Pang A; Chen B; Shen L; Yu H; Li J; Xu T; Wang Y; Yao X; Zhang B; Lin N; Dong X; Zhou Y; Che J
    J Med Chem; 2024 Jun; ():. PubMed ID: 38913763
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells.
    Xiao Z; Song S; Chen D; van Merkerk R; van der Wouden PE; Cool RH; Quax WJ; Poelarends GJ; Melgert BN; Dekker FJ
    Angew Chem Int Ed Engl; 2021 Aug; 60(32):17514-17521. PubMed ID: 34018657
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression.
    Qin C; Hu Y; Zhou B; Fernandez-Salas E; Yang CY; Liu L; McEachern D; Przybranowski S; Wang M; Stuckey J; Meagher J; Bai L; Chen Z; Lin M; Yang J; Ziazadeh DN; Xu F; Hu J; Xiang W; Huang L; Li S; Wen B; Sun D; Wang S
    J Med Chem; 2018 Aug; 61(15):6685-6704. PubMed ID: 30019901
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer.
    Han X; Zhao L; Xiang W; Qin C; Miao B; McEachern D; Wang Y; Metwally H; Wang L; Matvekas A; Wen B; Sun D; Wang S
    J Med Chem; 2021 Sep; 64(17):12831-12854. PubMed ID: 34431670
    [TBL] [Abstract][Full Text] [Related]  

  • 45. The role of histone lysine methyltransferase NSD3 in cancer.
    Han X; Piao L; Zhuang Q; Yuan X; Liu Z; He X
    Onco Targets Ther; 2018; 11():3847-3852. PubMed ID: 30013365
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Protective effect of histone methyltransferase NSD3 on ISO-induced cardiac hypertrophy.
    Chen K; Jian D; Zhao L; Zang X; Song W; Ma J; Jia Z; Wang X; Gao C
    FEBS Lett; 2019 Sep; 593(18):2556-2565. PubMed ID: 31254363
    [TBL] [Abstract][Full Text] [Related]  

  • 47. The PWWP domain of the human oncogene WHSC1L1/NSD3 induces a metabolic shift toward fermentation.
    Rona GB; Almeida DSG; Pinheiro AS; Eleutherio ECA
    Oncotarget; 2017 Aug; 8(33):54068-54081. PubMed ID: 28903324
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1.
    Hu M; Zhou W; Wang Y; Yao D; Ye T; Yao Y; Chen B; Liu G; Yang X; Wang W; Xie Y
    Acta Pharm Sin B; 2020 Oct; 10(10):1943-1953. PubMed ID: 33163345
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Backbone resonance assignments for the SET domain of human methyltransferase NSD3 in complex with its cofactor.
    Li Y; Ng HQ; Ngo A; Liu S; Tan YW; Kwek PZ; Hung AW; Joy J; Hill J; Keller TH; Kang C
    Biomol NMR Assign; 2017 Oct; 11(2):225-229. PubMed ID: 28808922
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Discovery of highly efficient CRBN-recruiting HPK1-PROTAC as a potential chemical tool for investigation of scaffolding roles in TCR signaling.
    Zeng S; Jin Y; Xia H; Shang Y; Li Y; Wang Z; Huang W
    Bioorg Chem; 2024 Feb; 143():107016. PubMed ID: 38086239
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression.
    Li Y; Yang J; Aguilar A; McEachern D; Przybranowski S; Liu L; Yang CY; Wang M; Han X; Wang S
    J Med Chem; 2019 Jan; 62(2):448-466. PubMed ID: 30525597
    [TBL] [Abstract][Full Text] [Related]  

  • 52. The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.
    Rahman S; Sowa ME; Ottinger M; Smith JA; Shi Y; Harper JW; Howley PM
    Mol Cell Biol; 2011 Jul; 31(13):2641-52. PubMed ID: 21555454
    [TBL] [Abstract][Full Text] [Related]  

  • 53. NSD3-NUT-expressing midline carcinoma of the lung: first characterization of primary cancer tissue.
    Suzuki S; Kurabe N; Ohnishi I; Yasuda K; Aoshima Y; Naito M; Tanioka F; Sugimura H
    Pathol Res Pract; 2015 May; 211(5):404-8. PubMed ID: 25466466
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Bivalent Ligands for Protein Degradation in Drug Discovery.
    Scheepstra M; Hekking KFW; van Hijfte L; Folmer RHA
    Comput Struct Biotechnol J; 2019; 17():160-176. PubMed ID: 30788082
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression.
    Zhou B; Hu J; Xu F; Chen Z; Bai L; Fernandez-Salas E; Lin M; Liu L; Yang CY; Zhao Y; McEachern D; Przybranowski S; Wen B; Sun D; Wang S
    J Med Chem; 2018 Jan; 61(2):462-481. PubMed ID: 28339196
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Discovery of the First Potent, Selective, and
    Sun Y; Xue Y; Sun P; Mu S; Liu H; Sun Y; Wang L; Wang J; Wu T; Yin W; Qin Q; Sun Y; Liu N; Wang H; Yang H; Zhao D; Cheng M
    J Med Chem; 2023 Jun; 66(12):8200-8221. PubMed ID: 37279162
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Discovery of BP3 as an efficacious proteolysis targeting chimera (PROTAC) degrader of HSP90 for treating breast cancer.
    Liu Q; Tu G; Hu Y; Jiang Q; Liu J; Lin S; Yu Z; Li G; Wu X; Tang Y; Huang X; Xu J; Liu Y; Wu L
    Eur J Med Chem; 2022 Jan; 228():114013. PubMed ID: 34864330
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Discovery of Small-Molecule Degraders for Alpha-Synuclein Aggregates.
    Tong Y; Zhu W; Chen J; Wen T; Xu F; Pang J
    J Med Chem; 2023 Jun; 66(12):7926-7942. PubMed ID: 37267712
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Dissecting the Immunological Profiles in
    Xu D; Liu S; Wu X; Marti TM; Dorn P; Schmid RA; Peng RW; Shu Y
    Cancers (Basel); 2022 Oct; 14(20):. PubMed ID: 36291782
    [TBL] [Abstract][Full Text] [Related]  

  • 60. A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro.
    Allali-Hassani A; Kuznetsova E; Hajian T; Wu H; Dombrovski L; Li Y; Gräslund S; Arrowsmith CH; Schapira M; Vedadi M
    J Biomol Screen; 2014 Jul; 19(6):928-35. PubMed ID: 24595546
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.