BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 35718804)

  • 1. Restricting α-synuclein transport into mitochondria by inhibition of α-synuclein-VDAC complexation as a potential therapeutic target for Parkinson's disease treatment.
    Rajendran M; Queralt-Martín M; Gurnev PA; Rosencrans WM; Rovini A; Jacobs D; Abrantes K; Hoogerheide DP; Bezrukov SM; Rostovtseva TK
    Cell Mol Life Sci; 2022 Jun; 79(7):368. PubMed ID: 35718804
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC.
    Rovini A; Gurnev PA; Beilina A; Queralt-Martín M; Rosencrans W; Cookson MR; Bezrukov SM; Rostovtseva TK
    Cell Mol Life Sci; 2020 Sep; 77(18):3611-3626. PubMed ID: 31760463
    [TBL] [Abstract][Full Text] [Related]  

  • 3. α-Synuclein emerges as a potent regulator of VDAC-facilitated calcium transport.
    Rosencrans WM; Aguilella VM; Rostovtseva TK; Bezrukov SM
    Cell Calcium; 2021 May; 95():102355. PubMed ID: 33578201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alpha-Synuclein and Mitochondrial Dysfunction in Parkinson's Disease: The Emerging Role of VDAC.
    Risiglione P; Zinghirino F; Di Rosa MC; Magrì A; Messina A
    Biomolecules; 2021 May; 11(5):. PubMed ID: 34064816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploring lipid-dependent conformations of membrane-bound α-synuclein with the VDAC nanopore.
    Hoogerheide DP; Rostovtseva TK; Bezrukov SM
    Biochim Biophys Acta Biomembr; 2021 Sep; 1863(9):183643. PubMed ID: 33971161
    [TBL] [Abstract][Full Text] [Related]  

  • 6. α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.
    Rostovtseva TK; Gurnev PA; Protchenko O; Hoogerheide DP; Yap TL; Philpott CC; Lee JC; Bezrukov SM
    J Biol Chem; 2015 Jul; 290(30):18467-77. PubMed ID: 26055708
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Voltage-activated complexation of α-synuclein with three diverse β-barrel channels: VDAC, MspA, and α-hemolysin.
    Hoogerheide DP; Gurnev PA; Rostovtseva TK; Bezrukov SM
    Proteomics; 2022 Mar; 22(5-6):e2100060. PubMed ID: 34813679
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of Mitochondrial Respiration by VDAC Is Enhanced by Membrane-Bound Inhibitors with Disordered Polyanionic C-Terminal Domains.
    Rostovtseva TK; Bezrukov SM; Hoogerheide DP
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298976
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway.
    Park JH; Burgess JD; Faroqi AH; DeMeo NN; Fiesel FC; Springer W; Delenclos M; McLean PJ
    Mol Neurodegener; 2020 Jan; 15(1):5. PubMed ID: 31931835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration.
    Wang X; Becker K; Levine N; Zhang M; Lieberman AP; Moore DJ; Ma J
    Acta Neuropathol Commun; 2019 Mar; 7(1):41. PubMed ID: 30871620
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.
    Blachly-Dyson E; Zambronicz EB; Yu WH; Adams V; McCabe ER; Adelman J; Colombini M; Forte M
    J Biol Chem; 1993 Jan; 268(3):1835-41. PubMed ID: 8420959
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Role of Voltage-Dependent Anion Channel in Mitochondrial Dysfunction and Human Disease.
    Varughese JT; Buchanan SK; Pitt AS
    Cells; 2021 Jul; 10(7):. PubMed ID: 34359907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein.
    Wang B; Underwood R; Kamath A; Britain C; McFerrin MB; McLean PJ; Volpicelli-Daley LA; Whitaker RH; Placzek WJ; Becker K; Ma J; Yacoubian TA
    J Neurosci; 2018 Sep; 38(38):8211-8232. PubMed ID: 30093536
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New findings concerning vertebrate porin II--on the relevance of glycine motifs of type-1 VDAC.
    Thinnes FP
    Mol Genet Metab; 2013 Apr; 108(4):212-24. PubMed ID: 23419876
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of the mitochondrial voltage-dependent anion channel (VDAC) by hydrogen peroxide and its recovery by curcumin.
    Malik C; Ghosh S
    Eur Biophys J; 2020 Oct; 49(7):661-672. PubMed ID: 33098437
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons.
    Pathak D; Berthet A; Bendor JT; Yu K; Sellnow RC; Orr AL; Nguyen MK; Edwards RH; Manfredsson FP; Nakamura K
    eNeuro; 2017; 4(2):. PubMed ID: 28462393
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
    Hu D; Sun X; Liao X; Zhang X; Zarabi S; Schimmer A; Hong Y; Ford C; Luo Y; Qi X
    Acta Neuropathol; 2019 Jun; 137(6):939-960. PubMed ID: 30877431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. VDAC inhibition by tubulin and its physiological implications.
    Rostovtseva TK; Bezrukov SM
    Biochim Biophys Acta; 2012 Jun; 1818(6):1526-35. PubMed ID: 22100746
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing Membrane Association of α-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding Pattern.
    Jacobs D; Hoogerheide DP; Rovini A; Jiang Z; Lee JC; Rostovtseva TK; Bezrukov SM
    Sci Rep; 2019 Mar; 9(1):4580. PubMed ID: 30872688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High expression of α-synuclein in damaged mitochondria with PLA2G6 dysfunction.
    Sumi-Akamaru H; Beck G; Shinzawa K; Kato S; Riku Y; Yoshida M; Fujimura H; Tsujimoto Y; Sakoda S; Mochizuki H
    Acta Neuropathol Commun; 2016 Mar; 4():27. PubMed ID: 27030050
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.