These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Belzutifan: a novel therapeutic for the management of von Hippel-Lindau disease and beyond. Curry L; Soleimani M Future Oncol; 2024; 20(18):1251-1266. PubMed ID: 38639572 [TBL] [Abstract][Full Text] [Related]
3. MK-6482 as a potential treatment for von Hippel-Lindau disease-associated clear cell renal cell carcinoma. Hasanov E; Jonasch E Expert Opin Investig Drugs; 2021 May; 30(5):495-504. PubMed ID: 33945366 [TBL] [Abstract][Full Text] [Related]
4. Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis. Clifford SC; Prowse AH; Affara NA; Buys CH; Maher ER Genes Chromosomes Cancer; 1998 Jul; 22(3):200-9. PubMed ID: 9624531 [TBL] [Abstract][Full Text] [Related]
5. Belzutifan: A Narrative Drug Review. Visweswaran V; Pavithran K Curr Drug Res Rev; 2022; 14(2):88-95. PubMed ID: 35366789 [TBL] [Abstract][Full Text] [Related]
6. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720 [TBL] [Abstract][Full Text] [Related]
7. Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma. Petrella BL; Lohi J; Brinckerhoff CE Oncogene; 2005 Feb; 24(6):1043-52. PubMed ID: 15592504 [TBL] [Abstract][Full Text] [Related]
8. Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. Zatyka M; da Silva NF; Clifford SC; Morris MR; Wiesener MS; Eckardt KU; Houlston RS; Richards FM; Latif F; Maher ER Cancer Res; 2002 Jul; 62(13):3803-11. PubMed ID: 12097293 [TBL] [Abstract][Full Text] [Related]
9. von-Hippel Lindau and Hypoxia-Inducible Factor at the Center of Renal Cell Carcinoma Biology. Shirole NH; Kaelin WG Hematol Oncol Clin North Am; 2023 Oct; 37(5):809-825. PubMed ID: 37270382 [TBL] [Abstract][Full Text] [Related]
10. Loss of Von Hippel-Lindau ( Kim H; Shim BY; Lee SJ; Lee JY; Lee HJ; Kim IH Int J Mol Sci; 2021 Sep; 22(18):. PubMed ID: 34575959 [TBL] [Abstract][Full Text] [Related]
11. Belzutifan in a Patient With VHL-Associated Metastatic Pancreatic Neuroendocrine Tumor. Pelle E; Al-Toubah T; Morse B; Strosberg J J Natl Compr Canc Netw; 2022 Dec; 20(12):1285-1287. PubMed ID: 36509068 [TBL] [Abstract][Full Text] [Related]
12. Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1 alpha expression in renal cell carcinomas. Na X; Wu G; Ryan CK; Schoen SR; di'Santagnese PA; Messing EM J Urol; 2003 Aug; 170(2 Pt 1):588-92. PubMed ID: 12853836 [TBL] [Abstract][Full Text] [Related]
13. Belzutifan, HIF-2α Inhibitor, and Clear Cell Renal Cell Carcinoma With Somatic Von-Hippel-Lindau Loss-of-Function Mutation. Chan KH; Li N; Lador R; Amsbaugh M; Gonzalez A; Cen P J Investig Med High Impact Case Rep; 2024; 12():23247096241231641. PubMed ID: 38344974 [TBL] [Abstract][Full Text] [Related]
14. Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease. Clifford SC; Cockman ME; Smallwood AC; Mole DR; Woodward ER; Maxwell PH; Ratcliffe PJ; Maher ER Hum Mol Genet; 2001 May; 10(10):1029-38. PubMed ID: 11331613 [TBL] [Abstract][Full Text] [Related]
16. Effect of radiation and ibuprofen on normoxic renal carcinoma cells overexpressing hypoxia-inducible factors by loss of von Hippel-Lindau tumor suppressor gene function. Palayoor ST; Burgos MA; Shoaibi A; Tofilon PJ; Coleman CN Clin Cancer Res; 2004 Jun; 10(12 Pt 1):4158-64. PubMed ID: 15217953 [TBL] [Abstract][Full Text] [Related]
17. Selective HIF2A Inhibitors in the Management of Clear Cell Renal Cancer and Von Hippel-Lindau-Disease-Associated Tumors. Suárez C; Vieito M; Valdivia A; González M; Carles J Med Sci (Basel); 2023 Jun; 11(3):. PubMed ID: 37489462 [TBL] [Abstract][Full Text] [Related]
18. The von Hippel-Lindau tumor suppressor gene and kidney cancer. Kaelin WG Clin Cancer Res; 2004 Sep; 10(18 Pt 2):6290S-5S. PubMed ID: 15448019 [TBL] [Abstract][Full Text] [Related]
19. Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity. Trotta AM; Santagata S; Zanotta S; D'Alterio C; Napolitano M; Rea G; Camerlingo R; Esposito F; Lamantia E; Anniciello A; Botti G; Longo N; Botti G; Pignata S; Perdonà S; Scala S J Exp Clin Cancer Res; 2018 Dec; 37(1):297. PubMed ID: 30514329 [TBL] [Abstract][Full Text] [Related]
20. Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma. Whaley JM; Naglich J; Gelbert L; Hsia YE; Lamiell JM; Green JS; Collins D; Neumann HP; Laidlaw J; Li FP Am J Hum Genet; 1994 Dec; 55(6):1092-102. PubMed ID: 7977367 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]