117 related articles for article (PubMed ID: 35731997)
21. NOTCH1 signaling as a therapeutic target in Sézary syndrome.
van der Fits L; Qin Y; Out-Luiting JJ; Vermeer KG; Whittaker S; van Es JH; Tensen CP; Vermeer MH
J Invest Dermatol; 2012 Dec; 132(12):2810-7. PubMed ID: 22718117
[TBL] [Abstract][Full Text] [Related]
22. Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction.
Kim SY; Kim MY; Mo JS; Park HS
Biochim Biophys Acta; 2007 Jun; 1773(6):736-46. PubMed ID: 17368826
[TBL] [Abstract][Full Text] [Related]
23. Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage.
Berezovska O; Jack C; Deng A; Gastineau N; Rebeck GW; Hyman BT
J Biol Chem; 2001 Aug; 276(32):30018-23. PubMed ID: 11408475
[TBL] [Abstract][Full Text] [Related]
24. Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism.
Secchiero P; Melloni E; di Iasio MG; Tiribelli M; Rimondi E; Corallini F; Gattei V; Zauli G
Blood; 2009 Apr; 113(18):4300-8. PubMed ID: 19190243
[TBL] [Abstract][Full Text] [Related]
25. Synergistic antileukemic therapies in
Sanchez-Martin M; Ambesi-Impiombato A; Qin Y; Herranz D; Bansal M; Girardi T; Paietta E; Tallman MS; Rowe JM; De Keersmaecker K; Califano A; Ferrando AA
Proc Natl Acad Sci U S A; 2017 Feb; 114(8):2006-2011. PubMed ID: 28174276
[TBL] [Abstract][Full Text] [Related]
26. Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia.
Mirandola L; Chiriva-Internati M; Montagna D; Locatelli F; Zecca M; Ranzani M; Basile A; Locati M; Cobos E; Kast WM; Asselta R; Paraboschi EM; Comi P; Chiaramonte R
J Pathol; 2012 Apr; 226(5):713-22. PubMed ID: 21984373
[TBL] [Abstract][Full Text] [Related]
27. Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc.
Sharma VM; Calvo JA; Draheim KM; Cunningham LA; Hermance N; Beverly L; Krishnamoorthy V; Bhasin M; Capobianco AJ; Kelliher MA
Mol Cell Biol; 2006 Nov; 26(21):8022-31. PubMed ID: 16954387
[TBL] [Abstract][Full Text] [Related]
28. Inhibition of the NOTCH pathway using γ-secretase inhibitor RO4929097 has limited antitumor activity in established glial tumors.
Dantas-Barbosa C; Bergthold G; Daudigeos-Dubus E; Blockus H; Boylan JF; Ferreira C; Puget S; Abely M; Vassal G; Grill J; Geoerger B
Anticancer Drugs; 2015 Mar; 26(3):272-83. PubMed ID: 25486598
[TBL] [Abstract][Full Text] [Related]
29. Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells.
Yang MS; Hong JS; Kim ST; Lee KY; Park KW; Kwon ST; Kweon DH; Koh YH; Gaiano N; Yoon K
Biochem Biophys Res Commun; 2011 Jan; 404(1):133-8. PubMed ID: 21108929
[TBL] [Abstract][Full Text] [Related]
30. Part 3: Notch-sparing γ-secretase inhibitors: SAR studies of 2-substituted aminopyridopyrimidinones.
Zhang J; Lu D; Wei HX; Gu Y; Selkoe DJ; Wolfe MS; Augelli-Szafran CE
Bioorg Med Chem Lett; 2016 May; 26(9):2138-41. PubMed ID: 27038496
[TBL] [Abstract][Full Text] [Related]
31. The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition.
Han J; Ma I; Hendzel MJ; Allalunis-Turner J
Breast Cancer Res; 2009; 11(4):R57. PubMed ID: 19660128
[TBL] [Abstract][Full Text] [Related]
32. Downregulation of Notch signaling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines.
Liu S; Breit S; Danckwardt S; Muckenthaler MU; Kulozik AE
Ann Hematol; 2009 Jul; 88(7):613-21. PubMed ID: 19057901
[TBL] [Abstract][Full Text] [Related]
33. The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells.
López-Guerra M; Xargay-Torrent S; Rosich L; Montraveta A; Roldán J; Matas-Céspedes A; Villamor N; Aymerich M; López-Otín C; Pérez-Galán P; Roué G; Campo E; Colomer D
Leukemia; 2015 Jan; 29(1):96-106. PubMed ID: 24781018
[TBL] [Abstract][Full Text] [Related]
34. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
Hales EC; Taub JW; Matherly LH
Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
[TBL] [Abstract][Full Text] [Related]
35. Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma.
Chang HH; Lee H; Hu MK; Tsao PN; Juan HF; Huang MC; Shih YY; Wang BJ; Jeng YM; Chang CL; Huang SF; Tsay YG; Hsieh FJ; Lin KH; Hsu WM; Liao YF
Clin Cancer Res; 2010 Sep; 16(17):4411-20. PubMed ID: 20736329
[TBL] [Abstract][Full Text] [Related]
36. Familial Alzheimer disease presenilin-1 mutations alter the active site conformation of γ-secretase.
Chau DM; Crump CJ; Villa JC; Scheinberg DA; Li YM
J Biol Chem; 2012 May; 287(21):17288-17296. PubMed ID: 22461631
[TBL] [Abstract][Full Text] [Related]
37. gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.
Meng RD; Shelton CC; Li YM; Qin LX; Notterman D; Paty PB; Schwartz GK
Cancer Res; 2009 Jan; 69(2):573-82. PubMed ID: 19147571
[TBL] [Abstract][Full Text] [Related]
38. NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.
Panaccione A; Chang MT; Carbone BE; Guo Y; Moskaluk CA; Virk RK; Chiriboga L; Prasad ML; Judson B; Mehra S; Yarbrough WG; Ivanov SV
Clin Cancer Res; 2016 Apr; 22(8):2083-95. PubMed ID: 27084744
[TBL] [Abstract][Full Text] [Related]
39. [Notch signaling pathway blocked by gamma-secretase inhibitor and its effect on the growth and apoptosis of SKOV3 cells].
Lu YL; Xie C
Sichuan Da Xue Xue Bao Yi Xue Ban; 2014 Jul; 45(4):578-81, 611. PubMed ID: 25286679
[TBL] [Abstract][Full Text] [Related]
40. Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein.
Sagi SA; Lessard CB; Winden KD; Maruyama H; Koo JC; Weggen S; Kukar TL; Golde TE; Koo EH
J Biol Chem; 2011 Nov; 286(46):39794-803. PubMed ID: 21868380
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
