BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 35737038)

  • 1. Correlation Investigation between Pyrrole-DNA and Pyrrole-Protein Adducts in Male ICR Mice Exposed to Retrorsine, a Hepatotoxic Pyrrolizidine Alkaloid.
    Zhu L; Xue J; He Y; Xia Q; Fu PP; Lin G
    Toxins (Basel); 2022 May; 14(6):. PubMed ID: 35737038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyrrolizidine Alkaloid-Induced Hepatotoxicity Associated with the Formation of Reactive Metabolite-Derived Pyrrole-Protein Adducts.
    Ma J; Li M; Li N; Chan WY; Lin G
    Toxins (Basel); 2021 Oct; 13(10):. PubMed ID: 34679016
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity.
    Lu Y; Ma J; Song Z; Ye Y; Fu PP; Lin G
    Arch Toxicol; 2018 Nov; 92(11):3403-3414. PubMed ID: 30244272
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity.
    Ma J; Xia Q; Fu PP; Lin G
    J Food Drug Anal; 2018 Jul; 26(3):965-972. PubMed ID: 29976414
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids.
    He X; Xia Q; Fu PP
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2017 Apr; 35(2):69-83. PubMed ID: 28418776
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Developing urinary pyrrole-amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human.
    Zhu L; Zhang C; Zhang W; Xia Q; Ma J; He X; He Y; Fu PP; Jia W; Zhuge Y; Lin G
    Arch Toxicol; 2021 Oct; 95(10):3191-3204. PubMed ID: 34390356
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo.
    Wang YP; Fu PP; Chou MW
    Int J Environ Res Public Health; 2005 Apr; 2(1):74-9. PubMed ID: 16705803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The long persistence of pyrrolizidine alkaloid-derived DNA adducts in vivo: kinetic study following single and multiple exposures in male ICR mice.
    Zhu L; Xue J; Xia Q; Fu PP; Lin G
    Arch Toxicol; 2017 Feb; 91(2):949-965. PubMed ID: 27125825
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides.
    He X; Xia Q; Woodling K; Lin G; Fu PP
    J Food Drug Anal; 2017 Oct; 25(4):984-991. PubMed ID: 28987376
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells.
    He X; Xia Q; Wu Q; Tolleson WH; Lin G; Fu PP
    Toxicol In Vitro; 2019 Feb; 54():286-294. PubMed ID: 30366057
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pulmonary toxicity is a common phenomenon of toxic pyrrolizidine alkaloids.
    Song Z; He Y; Ma J; Fu PP; Lin G
    J Environ Sci Health C Toxicol Carcinog; 2020; 38(2):124-140. PubMed ID: 32500835
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyrrolizidine Alkaloid Secondary Pyrrolic Metabolites Construct Multiple Activation Pathways Leading to DNA Adduct Formation and Potential Liver Tumor Initiation.
    Xia Q; He X; Ma L; Chen S; Fu PP
    Chem Res Toxicol; 2018 Jul; 31(7):619-628. PubMed ID: 29855181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyrrolizidine alkaloid-derived DNA adducts as a common biological biomarker of pyrrolizidine alkaloid-induced tumorigenicity.
    Xia Q; Zhao Y; Von Tungeln LS; Doerge DR; Lin G; Cai L; Fu PP
    Chem Res Toxicol; 2013 Sep; 26(9):1384-96. PubMed ID: 23937665
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity.
    Yang M; Ruan J; Fu PP; Lin G
    Chem Biol Interact; 2016 Jan; 243():119-26. PubMed ID: 26365561
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antibody-based detection of lysine modification of hepatic protein in mice treated with retrorsine.
    Cheng T; Li W; Yang X; Wang H; Zhang F; Li N; Lin G; Zheng J
    J Environ Sci Health C Toxicol Carcinog; 2020; 38(4):315-328. PubMed ID: 33382013
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 1-Formyl-7-hydroxy-6,7-dihydro-5 H-pyrrolizine (1-CHO-DHP): A Potential Proximate Carcinogenic Metabolite of Pyrrolizidine Alkaloids.
    He X; Xia Q; Gamboa da Costa G; Lin G; Fu PP
    Chem Res Toxicol; 2019 Jun; 32(6):1193-1203. PubMed ID: 31120748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans.
    Yang M; Ruan J; Gao H; Li N; Ma J; Xue J; Ye Y; Fu PP; Wang J; Lin G
    Arch Toxicol; 2017 Dec; 91(12):3913-3925. PubMed ID: 28620673
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The long persistence of pyrrolizidine alkaloid-derived pyrrole-protein adducts in vivo: Kinetic study following multiple exposures of a pyrrolizidine alkaloid containing extract of Gynura japonica.
    Chen Y; Xiong F; Wang W; Jiang K; Ye X; Deng G; Wang C; Yang L; Xiong A; Wang Z
    Toxicol Lett; 2020 May; 323():41-47. PubMed ID: 31982501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans.
    Ma J; Zhang W; He Y; Zhu L; Zhang C; Liu J; Ye Y; Zhuge Y; Lin G
    Arch Toxicol; 2021 Feb; 95(2):759-765. PubMed ID: 33210216
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolic activation of pyrrolizidine alkaloids: insights into the structural and enzymatic basis.
    Ruan J; Yang M; Fu P; Ye Y; Lin G
    Chem Res Toxicol; 2014 Jun; 27(6):1030-9. PubMed ID: 24836403
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.