128 related articles for article (PubMed ID: 35743098)
21. Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells.
Li L; Paz AC; Wilky BA; Johnson B; Galoian K; Rosenberg A; Hu G; Tinoco G; Bodamer O; Trent JC
PLoS One; 2015; 10(9):e0133813. PubMed ID: 26368816
[TBL] [Abstract][Full Text] [Related]
22. Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML.
Chaturvedi A; Araujo Cruz MM; Jyotsana N; Sharma A; Yun H; Görlich K; Wichmann M; Schwarzer A; Preller M; Thol F; Meyer J; Haemmerle R; Struys EA; Jansen EE; Modlich U; Li Z; Sly LM; Geffers R; Lindner R; Manstein DJ; Lehmann U; Krauter J; Ganser A; Heuser M
Blood; 2013 Oct; 122(16):2877-87. PubMed ID: 23954893
[TBL] [Abstract][Full Text] [Related]
23. Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart.
Karlstaedt A; Zhang X; Vitrac H; Harmancey R; Vasquez H; Wang JH; Goodell MA; Taegtmeyer H
Proc Natl Acad Sci U S A; 2016 Sep; 113(37):10436-41. PubMed ID: 27582470
[TBL] [Abstract][Full Text] [Related]
24. Wild-type IDH1 Knockout Leads to G0/G1 Arrest, Impairs Cancer Cell Proliferation, Altering Glycolysis, and the TCA Cycle in Colon Cancer.
Atalay EB; Senturk S; Kayali HA
Biochem Genet; 2023 Aug; 61(4):1470-1486. PubMed ID: 36633771
[TBL] [Abstract][Full Text] [Related]
25. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.
Seltzer MJ; Bennett BD; Joshi AD; Gao P; Thomas AG; Ferraris DV; Tsukamoto T; Rojas CJ; Slusher BS; Rabinowitz JD; Dang CV; Riggins GJ
Cancer Res; 2010 Nov; 70(22):8981-7. PubMed ID: 21045145
[TBL] [Abstract][Full Text] [Related]
26. Metabolic reprogramming in mutant IDH1 glioma cells.
Izquierdo-Garcia JL; Viswanath P; Eriksson P; Chaumeil MM; Pieper RO; Phillips JJ; Ronen SM
PLoS One; 2015; 10(2):e0118781. PubMed ID: 25706986
[TBL] [Abstract][Full Text] [Related]
27. Energy Metabolism in
van Noorden CJF; Hira VVV; van Dijck AJ; Novak M; Breznik B; Molenaar RJ
Cells; 2021 Mar; 10(3):. PubMed ID: 33810170
[TBL] [Abstract][Full Text] [Related]
28. Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency.
Avellaneda Matteo D; Grunseth AJ; Gonzalez ER; Anselmo SL; Kennedy MA; Moman P; Scott DA; Hoang A; Sohl CD
J Biol Chem; 2017 May; 292(19):7971-7983. PubMed ID: 28330869
[TBL] [Abstract][Full Text] [Related]
29. Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.
Cuyàs E; Fernández-Arroyo S; Corominas-Faja B; Rodríguez-Gallego E; Bosch-Barrera J; Martin-Castillo B; De Llorens R; Joven J; Menendez JA
Oncotarget; 2015 May; 6(14):12279-96. PubMed ID: 25980580
[TBL] [Abstract][Full Text] [Related]
30. Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
Molenaar RJ; Botman D; Smits MA; Hira VV; van Lith SA; Stap J; Henneman P; Khurshed M; Lenting K; Mul AN; Dimitrakopoulou D; van Drunen CM; Hoebe RA; Radivoyevitch T; Wilmink JW; Maciejewski JP; Vandertop WP; Leenders WP; Bleeker FE; van Noorden CJ
Cancer Res; 2015 Nov; 75(22):4790-802. PubMed ID: 26363012
[TBL] [Abstract][Full Text] [Related]
31. The Interactome between Metabolism and Gene Mutations in Myeloid Malignancies.
Gurnari C; Pagliuca S; Visconte V
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33808599
[TBL] [Abstract][Full Text] [Related]
32. The roles of IDH1 in tumor metabolism and immunity.
Ni Y; Shen P; Wang X; Liu H; Luo H; Han X
Future Oncol; 2022 Nov; 18(35):3941-3953. PubMed ID: 36621781
[TBL] [Abstract][Full Text] [Related]
33. Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death.
Mohrenz IV; Antonietti P; Pusch S; Capper D; Balss J; Voigt S; Weissert S; Mukrowsky A; Frank J; Senft C; Seifert V; von Deimling A; Kögel D
Apoptosis; 2013 Nov; 18(11):1416-1425. PubMed ID: 23801081
[TBL] [Abstract][Full Text] [Related]
34. RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer.
Zarei M; Lal S; Vaziri-Gohar A; O'Hayer K; Gunda V; Singh PK; Brody JR; Winter JM
Mol Cancer Res; 2019 Feb; 17(2):508-520. PubMed ID: 30266754
[TBL] [Abstract][Full Text] [Related]
35. Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase.
Izquierdo-Garcia JL; Cai LM; Chaumeil MM; Eriksson P; Robinson AE; Pieper RO; Phillips JJ; Ronen SM
PLoS One; 2014; 9(9):e108289. PubMed ID: 25243911
[TBL] [Abstract][Full Text] [Related]
36. Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.
Davis MI; Gross S; Shen M; Straley KS; Pragani R; Lea WA; Popovici-Muller J; DeLaBarre B; Artin E; Thorne N; Auld DS; Li Z; Dang L; Boxer MB; Simeonov A
J Biol Chem; 2014 May; 289(20):13717-25. PubMed ID: 24668804
[TBL] [Abstract][Full Text] [Related]
37. NADP+ -dependent IDH1 R132 mutation and its relevance for glioma patient survival.
Baldewpersad Tewarie NM; Burgers IA; Dawood Y; den Boon HC; den Brok MG; Klunder JH; Koopmans KB; Rademaker E; van den Broek HB; van den Bersselaar SM; Witjes JJ; Van Noorden CJ; Atai NA
Med Hypotheses; 2013 Jun; 80(6):728-31. PubMed ID: 23541771
[TBL] [Abstract][Full Text] [Related]
38. Discovery of new small molecule inhibitors targeting isocitrate dehydrogenase 1 (IDH1) with blood-brain barrier penetration.
Cao H; Zhu G; Sun L; Chen G; Ma X; Luo X; Zhu J
Eur J Med Chem; 2019 Dec; 183():111694. PubMed ID: 31561044
[TBL] [Abstract][Full Text] [Related]
39. Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma.
Lombardi G; Corona G; Bellu L; Della Puppa A; Pambuku A; Fiduccia P; Bertorelle R; Gardiman MP; D'Avella D; Toffoli G; Zagonel V
Oncologist; 2015 May; 20(5):562-7. PubMed ID: 25862748
[TBL] [Abstract][Full Text] [Related]
40. An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors.
Verdura S; Cuyàs E; Lozano-Sánchez J; Bastidas-Velez C; Llorach-Parés L; Fernández-Arroyo S; Hernández-Aguilera A; Joven J; Nonell-Canals A; Bosch-Barrera J; Martin-Castillo B; Vellon L; Sanchez-Martinez M; Segura-Carretero A; Menendez JA
Carcinogenesis; 2019 Mar; 40(1):27-40. PubMed ID: 30428017
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
