BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 35745567)

  • 1. Novel Effects of Statins on Cancer via Autophagy.
    Mengual D; Medrano LE; Villamizar-Villamizar W; Osorio-Llanes E; Mendoza-Torres E; Bolívar S
    Pharmaceuticals (Basel); 2022 May; 15(6):. PubMed ID: 35745567
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway.
    Liu F; Gao S; Yang Y; Zhao X; Fan Y; Ma W; Yang D; Yang A; Yu Y
    Oncol Rep; 2018 Mar; 39(3):1523-1531. PubMed ID: 29328421
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway.
    Lu T; Zhu Z; Wu J; She H; Han R; Xu H; Qin ZH
    Cell Commun Signal; 2019 Mar; 17(1):28. PubMed ID: 30902093
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway.
    Polivka J; Janku F
    Pharmacol Ther; 2014 May; 142(2):164-75. PubMed ID: 24333502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells.
    Berrak O; Arisan ED; Obakan-Yerlikaya P; Coker-Gürkan A; Palavan-Unsal N
    Apoptosis; 2016 Oct; 21(10):1158-78. PubMed ID: 27484210
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F; Li H; Yan XG; Zhou ZW; Yi ZG; He ZX; Pan ST; Yang YX; Wang ZZ; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST; Qin Y; Zhou ZW; He ZX; Zhang X; Yang T; Yang YX; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1601-26. PubMed ID: 25834400
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Statin-mediated inhibition of cholesterol synthesis induces cytoprotective autophagy in human leukemic cells.
    Vilimanovich U; Bosnjak M; Bogdanovic A; Markovic I; Isakovic A; Kravic-Stevovic T; Mircic A; Trajkovic V; Bumbasirevic V
    Eur J Pharmacol; 2015 Oct; 765():415-28. PubMed ID: 26358205
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Pan SY; Chen XW; Zhou SF
    Drug Des Devel Ther; 2015; 9():1293-318. PubMed ID: 25767376
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells.
    Kim SY; Hwangbo H; Kim MY; Ji SY; Lee H; Kim GY; Kwon CY; Leem SH; Hong SH; Cheong J; Choi YH
    Arch Biochem Biophys; 2021 Jan; 697():108688. PubMed ID: 33227289
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways.
    Aoki H; Takada Y; Kondo S; Sawaya R; Aggarwal BB; Kondo Y
    Mol Pharmacol; 2007 Jul; 72(1):29-39. PubMed ID: 17395690
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Role of Non-Coding RNAs in Autophagy During Carcinogenesis.
    de la Cruz-Ojeda P; Flores-Campos R; Navarro-Villarán E; Muntané J
    Front Cell Dev Biol; 2022; 10():799392. PubMed ID: 35309939
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RCE‑4, a potential anti‑cervical cancer drug isolated from Reineckia carnea, induces autophagy via the dual blockade of PI3K and ERK pathways in cervical cancer CaSki cells.
    Xiang W; Zhang RJ; Jin GL; Tian L; Cheng F; Wang JZ; Xing XF; Xi W; Tang SJ; Chen JF
    Int J Mol Med; 2020 Jan; 45(1):245-254. PubMed ID: 31746346
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/Akt/mammalian target of rapamycin and glycogen synthase kinase-3 beta signalling cascades in experimental colon carcinogenesis.
    Saiprasad G; Chitra P; Manikandan R; Sudhandiran G
    Eur J Cancer; 2014 Sep; 50(14):2489-507. PubMed ID: 25047426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The effect of JAK2 knockout on inhibition of liver tumor growth by inducing apoptosis, autophagy and anti-proliferation via STATs and PI3K/AKT signaling pathways.
    Xu Y; Lv SX
    Biomed Pharmacother; 2016 Dec; 84():1202-1212. PubMed ID: 27788478
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gefitinib induces lung cancer cell autophagy and apoptosis via blockade of the PI3K/AKT/mTOR pathway.
    Zhao ZQ; Yu ZY; Li J; Ouyang XN
    Oncol Lett; 2016 Jul; 12(1):63-68. PubMed ID: 27347100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
    Hu X; Xia M; Wang J; Yu H; Chai J; Zhang Z; Sun Y; Su J; Sun L
    Biomed Pharmacother; 2020 Sep; 129():110397. PubMed ID: 32585451
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autophagy inhibition enhances colorectal cancer apoptosis induced by dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
    Yang X; Niu B; Wang L; Chen M; Kang X; Wang L; Ji Y; Zhong J
    Oncol Lett; 2016 Jul; 12(1):102-106. PubMed ID: 27347108
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.