These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 35745697)

  • 1. Nobiletin as a Neuroprotectant against NMDA Receptors: An In Silico Approach.
    Jahan S; Redhu NS; Siddiqui AJ; Iqbal D; Khan J; Banawas S; Alaidarous M; Alshehri B; Mir SA; Adnan M; Pant AB
    Pharmaceutics; 2022 May; 14(6):. PubMed ID: 35745697
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An in-silico investigation based on molecular simulations of novel and potential brain-penetrant GluN2B NMDA receptor antagonists as anti-stroke therapeutic agents.
    El Fadili M; Er-Rajy M; Ali Eltayb W; Kara M; Imtara H; Zarougui S; Al-Hoshani N; Hamadi A; Elhallaoui M
    J Biomol Struct Dyn; 2024 Aug; 42(12):6174-6188. PubMed ID: 37428078
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutamate receptor antibodies in neurological diseases: anti-AMPA-GluR3 antibodies, anti-NMDA-NR1 antibodies, anti-NMDA-NR2A/B antibodies, anti-mGluR1 antibodies or anti-mGluR5 antibodies are present in subpopulations of patients with either: epilepsy, encephalitis, cerebellar ataxia, systemic lupus erythematosus (SLE) and neuropsychiatric SLE, Sjogren's syndrome, schizophrenia, mania or stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate receptors, decrease glutamate receptor's expression, impair glutamate-induced signaling and function, activate blood brain barrier endothelial cells, kill neurons, damage the brain, induce behavioral/psychiatric/cognitive abnormalities and ataxia in animal models, and can be removed or silenced in some patients by immunotherapy.
    Levite M
    J Neural Transm (Vienna); 2014 Aug; 121(8):1029-75. PubMed ID: 25081016
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of
    Hu S; Hu H; Mak S; Cui G; Lee M; Shan L; Wang Y; Lin H; Zhang Z; Han Y
    Front Pharmacol; 2018; 9():73. PubMed ID: 29483871
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of action of neuroprotectants in stroke.
    Lyden P; Wahlgren NG
    J Stroke Cerebrovasc Dis; 2000 Nov; 9(6 Pt 2):9-14. PubMed ID: 17895214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity.
    Planells-Cases R; Montoliu C; Humet M; Fernández AM; García-Martínez C; Valera E; Merino JM; Pérez-Payá E; Messeguer A; Felipo V; Ferrer-Montiel A
    J Pharmacol Exp Ther; 2002 Jul; 302(1):163-73. PubMed ID: 12065713
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study.
    Kumar G; Patnaik R
    Med Hypotheses; 2016 Jul; 92():35-43. PubMed ID: 27241252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade.
    Al Rahim M; Nakajima A; Saigusa D; Tetsu N; Maruyama Y; Shibuya M; Yamakoshi H; Tomioka Y; Iwabuchi Y; Ohizumi Y; Yamakuni T
    Biochemistry; 2009 Aug; 48(32):7713-21. PubMed ID: 19601643
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-Based Multi-Targeted Molecular Docking and Dynamic Simulation of Soybean-Derived Isoflavone Genistin as a Potential Breast Cancer Signaling Proteins Inhibitor.
    Elkhalifa AEO; Al-Shammari E; Kuddus M; Adnan M; Sachidanandan M; Awadelkareem AM; Qattan MY; Khan MI; Abduljabbar SI; Sarwar Baig M; Ashraf SA
    Life (Basel); 2023 Aug; 13(8):. PubMed ID: 37629596
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Screening, Docking, and Molecular Dynamics Study of Natural Compounds as an Anti-HER2 for the Management of Breast Cancer.
    Sohrab SS; Kamal MA
    Life (Basel); 2022 Oct; 12(11):. PubMed ID: 36362883
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nobiletin, a citrus flavonoid, reverses learning impairment associated with N-methyl-D-aspartate receptor antagonism by activation of extracellular signal-regulated kinase signaling.
    Nakajima A; Yamakuni T; Matsuzaki K; Nakata N; Onozuka H; Yokosuka A; Sashida Y; Mimaki Y; Ohizumi Y
    J Pharmacol Exp Ther; 2007 May; 321(2):784-90. PubMed ID: 17289833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir.
    Merz SF; Bengtson CP; Tepohl C; Hagenston AM; Bading H; Bas-Orth C
    Mol Brain; 2020 Sep; 13(1):124. PubMed ID: 32928261
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by N-methyl-D-aspartate receptors.
    Wang H; Gong B; Vadakkan KI; Toyoda H; Kaang BK; Zhuo M
    J Biol Chem; 2007 Jan; 282(2):1507-17. PubMed ID: 17121841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevention of in vivo excitotoxicity by a family of trialkylglycines, a novel class of neuroprotectants.
    Montoliu C; Humet M; Canales JJ; Burda J; Planells-Cases R; Sánchez-Baeza F; Carbonell T; Pérez-Payá E; Messeguer A; Ferrer-Montiel A; Felipo V
    J Pharmacol Exp Ther; 2002 Apr; 301(1):29-36. PubMed ID: 11907154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inflammatory mediators leading to protein misfolding and uncompetitive/fast off-rate drug therapy for neurodegenerative disorders.
    Lipton SA; Gu Z; Nakamura T
    Int Rev Neurobiol; 2007; 82():1-27. PubMed ID: 17678953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and Biological Evaluation of Novel Multi-target-Directed Benzazepines Against Excitotoxicity.
    Machhi J; Prajapati N; Tripathi A; Parikh ZS; Kanhed AM; Patel K; Pillai PP; Giridhar R; Yadav MR
    Mol Neurobiol; 2017 Nov; 54(9):6697-6722. PubMed ID: 27744571
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons.
    Valera E; Fernández-Salguero PM; Planells-Cases R; Messeguer A; Van Den Nest W; Carreño C; Ferrer-Montiel A; Merino JM
    Neuromolecular Med; 2002; 2(3):271-80. PubMed ID: 12622405
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway.
    Zhu D; Wu X; Strauss KI; Lipsky RH; Qureshi Z; Terhakopian A; Novelli A; Banaudha K; Marini AM
    J Neurosci Res; 2005 Apr; 80(1):104-13. PubMed ID: 15744743
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
    Chen Q; Surmeier DJ; Reiner A
    Exp Neurol; 1999 Sep; 159(1):283-96. PubMed ID: 10486197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro.
    Sinor JD; Du S; Venneti S; Blitzblau RC; Leszkiewicz DN; Rosenberg PA; Aizenman E
    J Neurosci; 2000 Dec; 20(23):8831-7. PubMed ID: 11102491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.