196 related articles for article (PubMed ID: 35752212)
1. Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP.
Grudzien P; Jang H; Leschinsky N; Nussinov R; Gaponenko V
J Mol Biol; 2022 Sep; 434(17):167695. PubMed ID: 35752212
[TBL] [Abstract][Full Text] [Related]
2. The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.
Lu S; Jang H; Nussinov R; Zhang J
Sci Rep; 2016 Feb; 6():21949. PubMed ID: 26902995
[TBL] [Abstract][Full Text] [Related]
3. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
Lu S; Banerjee A; Jang H; Zhang J; Gaponenko V; Nussinov R
J Biol Chem; 2015 Nov; 290(48):28887-900. PubMed ID: 26453300
[TBL] [Abstract][Full Text] [Related]
4. The higher level of complexity of K-Ras4B activation at the membrane.
Jang H; Banerjee A; Chavan TS; Lu S; Zhang J; Gaponenko V; Nussinov R
FASEB J; 2016 Apr; 30(4):1643-55. PubMed ID: 26718888
[TBL] [Abstract][Full Text] [Related]
5. Mutational landscape of K-Ras substitutions at 12th position-a systematic molecular dynamics approach.
S UK; R B; D TK; Doss CGP; Zayed H
J Biomol Struct Dyn; 2022 Mar; 40(4):1571-1585. PubMed ID: 33034275
[TBL] [Abstract][Full Text] [Related]
6. Distinct dynamics and interaction patterns in H- and K-Ras oncogenic P-loop mutants.
Sayyed-Ahmad A; Prakash P; Gorfe AA
Proteins; 2017 Sep; 85(9):1618-1632. PubMed ID: 28498561
[TBL] [Abstract][Full Text] [Related]
7. Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Xu S; Long BN; Boris GH; Chen A; Ni S; Kennedy MA
Acta Crystallogr D Struct Biol; 2017 Dec; 73(Pt 12):970-984. PubMed ID: 29199977
[TBL] [Abstract][Full Text] [Related]
8.
Pálfy G; Vida I; Perczel A
Biomol NMR Assign; 2020 Apr; 14(1):1-7. PubMed ID: 31468366
[TBL] [Abstract][Full Text] [Related]
9. An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras.
Miller AF; Halkides CJ; Redfield AG
Biochemistry; 1993 Jul; 32(29):7367-76. PubMed ID: 8338834
[TBL] [Abstract][Full Text] [Related]
10. NMR
Yuan C; Hansen AL; Bruschweiler-Li L; Brüschweiler R
Biomol NMR Assign; 2024 Jun; 18(1):7-13. PubMed ID: 37948018
[TBL] [Abstract][Full Text] [Related]
11. Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
Mazhab-Jafari MT; Marshall CB; Smith MJ; Gasmi-Seabrook GM; Stathopulos PB; Inagaki F; Kay LE; Neel BG; Ikura M
Proc Natl Acad Sci U S A; 2015 May; 112(21):6625-30. PubMed ID: 25941399
[TBL] [Abstract][Full Text] [Related]
12. Comparison of ras-p21 bound to GDP and GTP: differences in protein and ligand dynamics.
Mello LV; van Aalten DM; Findlay JB
Protein Eng; 1997 Apr; 10(4):381-7. PubMed ID: 9194162
[TBL] [Abstract][Full Text] [Related]
13. Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.
Al-Mulla F; Milner-White EJ; Going JJ; Birnie GD
J Pathol; 1999 Mar; 187(4):433-8. PubMed ID: 10398103
[TBL] [Abstract][Full Text] [Related]
14. Oncogenic G12D mutation alters local conformations and dynamics of K-Ras.
Vatansever S; Erman B; Gümüş ZH
Sci Rep; 2019 Aug; 9(1):11730. PubMed ID: 31409810
[TBL] [Abstract][Full Text] [Related]
15. Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
Gentile DR; Rathinaswamy MK; Jenkins ML; Moss SM; Siempelkamp BD; Renslo AR; Burke JE; Shokat KM
Cell Chem Biol; 2017 Dec; 24(12):1455-1466.e14. PubMed ID: 29033317
[TBL] [Abstract][Full Text] [Related]
16. High-frequency 94 GHz ENDOR characterization of the metal binding site in wild-type Ras x GDP and its oncogenic mutant G12V in frozen solution.
Bennati M; Hertel MM; Fritscher J; Prisner TF; Weiden N; Hofweber R; Spörner M; Horn G; Kalbitzer HR
Biochemistry; 2006 Jan; 45(1):42-50. PubMed ID: 16388579
[TBL] [Abstract][Full Text] [Related]
17. K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D.
Parker JA; Volmar AY; Pavlopoulos S; Mattos C
Structure; 2018 Jun; 26(6):810-820.e4. PubMed ID: 29706533
[TBL] [Abstract][Full Text] [Related]
18. Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics.
Haspel N; Jang H; Nussinov R
Biophys J; 2021 Jan; 120(2):306-318. PubMed ID: 33347888
[TBL] [Abstract][Full Text] [Related]
19. Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by
Sharma AK; Pei J; Yang Y; Dyba M; Smith B; Rabara D; Larsen EK; Lightstone FC; Esposito D; Stephen AG; Wang B; Beltran PJ; Wallace E; Nissley DV; McCormick F; Maciag AE
J Biol Chem; 2024 Feb; 300(2):105650. PubMed ID: 38237681
[TBL] [Abstract][Full Text] [Related]
20. Conformational states of human rat sarcoma (Ras) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis.
Spoerner M; Hozsa C; Poetzl JA; Reiss K; Ganser P; Geyer M; Kalbitzer HR
J Biol Chem; 2010 Dec; 285(51):39768-78. PubMed ID: 20937837
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]