BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 35752377)

  • 1. Functional in vitro characterization of SLCO1B1 variants and simulation of the clinical pharmacokinetic impact of impaired OATP1B1 function.
    Kiander W; Sjöstedt N; Manninen R; Jaakkonen L; Vellonen KS; Neuvonen M; Niemi M; Auriola S; Kidron H
    Eur J Pharm Sci; 2022 Sep; 176():106246. PubMed ID: 35752377
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality.
    Kiander W; Vellonen KS; Malinen MM; Gynther M; Hagström M; Bhattacharya M; Auriola S; Koenderink JB; Kidron H
    Pharm Res; 2021 Oct; 38(10):1663-1675. PubMed ID: 34647232
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional Characterization of Six
    Häkkinen K; Kiander W; Kidron H; Lähteenvuo M; Urpa L; Lintunen J; Vellonen KS; Auriola S; Holm M; Lahdensuo K; Kampman O; Isometsä E; Kieseppä T; Lönnqvist J; Suvisaari J; Hietala J; Tiihonen J; Palotie A; Ahola-Olli AV; Niemi M
    Mol Pharm; 2023 Mar; 20(3):1500-1508. PubMed ID: 36779498
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.
    Nassif A; Jia J; Keiser M; Oswald S; Modess C; Nagel S; Weitschies W; Hosten N; Siegmund W; Kühn JP
    Radiology; 2012 Sep; 264(3):741-50. PubMed ID: 22771883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1.
    van de Steeg E; Greupink R; Schreurs M; Nooijen IH; Verhoeckx KC; Hanemaaijer R; Ripken D; Monshouwer M; Vlaming ML; DeGroot J; Verwei M; Russel FG; Huisman MT; Wortelboer HM
    Drug Metab Dispos; 2013 Mar; 41(3):592-601. PubMed ID: 23248200
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors.
    Choi MK; Shin HJ; Choi YL; Deng JW; Shin JG; Song IS
    Xenobiotica; 2011 Jan; 41(1):24-34. PubMed ID: 20946088
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake.
    Niemi M; Pasanen MK; Neuvonen PJ
    Pharmacol Rev; 2011 Mar; 63(1):157-81. PubMed ID: 21245207
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes.
    Takahashi T; Uno Y; Yamazaki H; Kume T
    Biopharm Drug Dispos; 2019 Feb; 40(2):62-69. PubMed ID: 30652318
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interindividual and interethnic variability in drug disposition: polymorphisms in organic anion transporting polypeptide 1B1 (OATP1B1; SLCO1B1).
    Lee HH; Ho RH
    Br J Clin Pharmacol; 2017 Jun; 83(6):1176-1184. PubMed ID: 27936281
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Construction of HEK293 cells stably expressing wild-type organic anion transporting polypeptide 1B1 (OATP1B1*1a) and variant OATP1B1*1b and OATP1B1*15.
    Chen M; Qu BX; Chen XL; Hu HH; Jiang HD; Yu LS; Zhou Q; Zeng S
    Pharmazie; 2016 Jun; 71(6):337-9. PubMed ID: 27455553
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fevipiprant has a low risk of influencing co-medication pharmacokinetics: Impact on simvastatin and rosuvastatin in different SLCO1B1 genotypes.
    Poller B; Woessner R; Barve A; Tillmann HC; Vemula J; Nica A; Elbast W; Schiller H; End P; Camenisch G; Weiss M
    Pulm Pharmacol Ther; 2019 Aug; 57():101809. PubMed ID: 31195091
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fentanyl pharmacokinetics is not dependent on hepatic uptake by organic anion-transporting polypeptide 1B1 in human beings.
    Ziesenitz VC; König SK; Mahlke N; Jantos R; Skopp G; Weiss J; Haefeli WE; Mikus G
    Basic Clin Pharmacol Toxicol; 2013 Jul; 113(1):43-8. PubMed ID: 23480028
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells.
    Liu J; Guo Y; Liu K; Ye X; Wang F; Xu Y; Xia C
    Sci Rep; 2020 Jan; 10(1):1308. PubMed ID: 31992796
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of Glycochenodeoxycholate 3-O-Glucuronide and Glycodeoxycholate 3-O-Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers.
    Neuvonen M; Hirvensalo P; Tornio A; Rago B; West M; Lazzaro S; Mathialagan S; Varma M; Cerny MA; Costales C; Ramanathan R; Rodrigues AD; Niemi M
    Clin Pharmacol Ther; 2021 Mar; 109(3):646-657. PubMed ID: 32961594
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis.
    Li R; Barton HA
    Clin Pharmacokinet; 2018 Apr; 57(4):491-503. PubMed ID: 28653144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism.
    Crowe A; Zheng W; Miller J; Pahwa S; Alam K; Fung KM; Rubin E; Yin F; Ding K; Yue W
    Pharm Res; 2019 May; 36(7):101. PubMed ID: 31093828
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dissecting the Contribution of OATP1B1 to Hepatic Uptake of Statins Using the OATP1B1 Selective Inhibitor Estropipate.
    Zhang Y; Panfen E; Fancher M; Sinz M; Marathe P; Shen H
    Mol Pharm; 2019 Jun; 16(6):2342-2353. PubMed ID: 31039308
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.
    Kunze A; Huwyler J; Camenisch G; Poller B
    Drug Metab Dispos; 2014 Sep; 42(9):1514-21. PubMed ID: 24989890
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex.
    Prasad B; Evers R; Gupta A; Hop CE; Salphati L; Shukla S; Ambudkar SV; Unadkat JD
    Drug Metab Dispos; 2014 Jan; 42(1):78-88. PubMed ID: 24122874
    [TBL] [Abstract][Full Text] [Related]  

  • 20. OATP1B1-related drug-drug and drug-gene interactions as potential risk factors for cerivastatin-induced rhabdomyolysis.
    Tamraz B; Fukushima H; Wolfe AR; Kaspera R; Totah RA; Floyd JS; Ma B; Chu C; Marciante KD; Heckbert SR; Psaty BM; Kroetz DL; Kwok PY
    Pharmacogenet Genomics; 2013 Jul; 23(7):355-64. PubMed ID: 23652407
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.