BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 35754740)

  • 1. Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A.
    Narayan S; Raza A; Mahmud I; Koo N; Garrett TJ; Law ME; Law BK; Sharma AK
    iScience; 2022 Jul; 25(7):104518. PubMed ID: 35754740
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations.
    Narayan S; Jaiswal AS; Sharma R; Nawab A; Duckworth LV; Law BK; Zajac-Kaye M; George TJ; Sharma J; Sharma AK; Hromas RA
    Oncotarget; 2017 Aug; 8(34):57246-57264. PubMed ID: 28915668
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.
    Narayan S; Ramisetti S; Jaiswal AS; Law BK; Singh-Pillay A; Singh P; Amin S; Sharma AK
    Eur J Med Chem; 2019 Jan; 161():456-467. PubMed ID: 30384048
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-associated p38 mitogen-activated protein kinase.
    Boudreau RT; Conrad DM; Hoskin DW
    Cell Signal; 2007 Jan; 19(1):139-51. PubMed ID: 16844342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells.
    Li X; Li Z; Zhou W; Xing X; Huang L; Tian L; Chen J; Chen C; Ma X; Yang Z
    Cell Death Dis; 2013 Sep; 4(9):e803-9. PubMed ID: 24030155
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.
    Li Y; Wang X; Yue P; Tao H; Ramalingam SS; Owonikoko TK; Deng X; Wang Y; Fu H; Khuri FR; Sun SY
    J Biol Chem; 2013 May; 288(19):13215-24. PubMed ID: 23536185
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis.
    Xu J; Xu Z; Zhou JY; Zhuang Z; Wang E; Boerner J; Wu GS
    J Biol Chem; 2013 Nov; 288(46):33263-71. PubMed ID: 24100030
    [TBL] [Abstract][Full Text] [Related]  

  • 8. mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity.
    Jin ZZ; Wang W; Fang DL; Jin YJ
    Biochem Biophys Res Commun; 2016 Sep; 478(4):1515-20. PubMed ID: 27565731
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Chen KF; Yeh PY; Hsu C; Hsu CH; Lu YS; Hsieh HP; Chen PJ; Cheng AL
    J Biol Chem; 2009 Apr; 284(17):11121-33. PubMed ID: 19261616
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells.
    Lashinger LM; Zhu K; Williams SA; Shrader M; Dinney CP; McConkey DJ
    Cancer Res; 2005 Jun; 65(11):4902-8. PubMed ID: 15930312
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP.
    Zhang T; Wang X; He D; Jin X; Guo P
    Anticancer Drugs; 2014 Sep; 25(8):887-97. PubMed ID: 24714080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.
    Hamaï A; Richon C; Meslin F; Faure F; Kauffmann A; Lecluse Y; Jalil A; Larue L; Avril MF; Chouaib S; Mehrpour M
    Oncogene; 2006 Dec; 25(58):7618-34. PubMed ID: 16983347
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate.
    Chai F; Evdokiou A; Young GP; Zalewski PD
    Carcinogenesis; 2000 Jan; 21(1):7-14. PubMed ID: 10607727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis.
    Hernandez A; Thomas R; Smith F; Sandberg J; Kim S; Chung DH; Evers BM
    Surgery; 2001 Aug; 130(2):265-72. PubMed ID: 11490359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FL118 inhibits viability and induces apoptosis of colorectal cancer cells via inactivating the CIP2A/PP2A axis.
    Lin X; Gao M; Zhang A; Tong J; Zhang X; Su Q; Yang Z; Gao H; Jiang G
    Life Sci; 2019 Dec; 239():117074. PubMed ID: 31751585
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Caspase-2 primes cancer cells for TRAIL-mediated apoptosis by processing procaspase-8.
    Shin S; Lee Y; Kim W; Ko H; Choi H; Kim K
    EMBO J; 2005 Oct; 24(20):3532-42. PubMed ID: 16193064
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hyperphosphorylation of PP2A in colorectal cancer and the potential therapeutic value showed by its forskolin-induced dephosphorylation and activation.
    Cristóbal I; Rincón R; Manso R; Madoz-Gúrpide J; Caramés C; del Puerto-Nevado L; Rojo F; García-Foncillas J
    Biochim Biophys Acta; 2014 Sep; 1842(9):1823-9. PubMed ID: 24997451
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway.
    Chou AH; Tsai HF; Wu YY; Hu CY; Hwang LH; Hsu PI; Hsu PN
    J Immunol; 2005 Feb; 174(4):2160-6. PubMed ID: 15699147
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation.
    Kim EH; Yoon MJ; Kim SU; Kwon TK; Sohn S; Choi KS
    Cancer Res; 2008 Jan; 68(1):266-75. PubMed ID: 18172319
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of PP2A activity confers a TRAIL-sensitive phenotype during malignant transformation.
    Yang H; Chen X; Wang X; Li Y; Chen S; Qian X; Wang R; Chen L; Han W; Ruan A; Du Q; Olumi AF; Zhang X
    Mol Cancer Res; 2014 Feb; 12(2):217-27. PubMed ID: 24296757
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.