170 related articles for article (PubMed ID: 35767003)
1. Suppression of phosphodiesterase IV enzyme by roflumilast ameliorates cognitive dysfunction in aged rats after sevoflurane anaesthesia via PKA-CREB and MEK/ERK pathways.
Liu P; Wang J; Peng S; Zhang D; Zhuang L; Liu C; Zhang Y; Shi X
Eur J Neurosci; 2022 Aug; 56(4):4317-4332. PubMed ID: 35767003
[TBL] [Abstract][Full Text] [Related]
2. Phosphodiesterase 4 Inhibitor Roflumilast Protects Rat Hippocampal Neurons from Sevoflurane Induced Injury via Modulation of MEK/ERK Signaling Pathway.
Peng S; Yan HZ; Liu PR; Shi XW; Liu CL; Liu Q; Zhang Y
Cell Physiol Biochem; 2018; 45(6):2329-2337. PubMed ID: 29550808
[TBL] [Abstract][Full Text] [Related]
3. Phoenixin-20 ameliorates Sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of the PKA/CREB signaling.
Zhang J; Wang Z; Cong K; Qi J; Sun L
Aging (Albany NY); 2023 Dec; 15(24):14666-14676. PubMed ID: 38103264
[TBL] [Abstract][Full Text] [Related]
4. Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats.
Qiu Y; Wang Y; Wang X; Wang C; Xia ZY
J Int Med Res; 2018 Mar; 46(3):1073-1085. PubMed ID: 29332488
[TBL] [Abstract][Full Text] [Related]
5. Dexmedetomidine protects rats from postoperative cognitive dysfunction via regulating the GABA
Zhu YS; Xiong YF; Luo FQ; Min J
Neuropathology; 2019 Feb; 39(1):30-38. PubMed ID: 30592096
[TBL] [Abstract][Full Text] [Related]
6. PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways.
Kwak HJ; Park KM; Choi HE; Chung KS; Lim HJ; Park HY
Cell Signal; 2008 May; 20(5):803-14. PubMed ID: 18276108
[TBL] [Abstract][Full Text] [Related]
7. Roflumilast ameliorates cognitive impairment in APP/PS1 mice via cAMP/CREB/BDNF signaling and anti-neuroinflammatory effects.
Feng H; Wang C; He W; Wu X; Li S; Zeng Z; Wei M; He B
Metab Brain Dis; 2019 Apr; 34(2):583-591. PubMed ID: 30610438
[TBL] [Abstract][Full Text] [Related]
8. Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system.
Jabaris SS; Sumathy H; Girish R; Narayanan S; Sugumar M; Saravana Babu C; Thanikachalam S; Thanikachalam M
Brain Res; 2015 Oct; 1622():279-91. PubMed ID: 26168894
[TBL] [Abstract][Full Text] [Related]
9. Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway.
Liu TJ; Zhang JC; Gao XZ; Tan ZB; Wang JJ; Zhang PP; Cheng AB; Zhang SB
Kaohsiung J Med Sci; 2018 Jan; 34(1):22-33. PubMed ID: 29310813
[TBL] [Abstract][Full Text] [Related]
10. Phosphodiestrase-1 and 4 inhibitors ameliorate liver fibrosis in rats: Modulation of cAMP/CREB/TLR4 inflammatory and fibrogenic pathways.
Essam RM; Ahmed LA; Abdelsalam RM; El-Khatib AS
Life Sci; 2019 Apr; 222():245-254. PubMed ID: 30858122
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus.
Zhang HT; Zhao Y; Huang Y; Dorairaj NR; Chandler LJ; O'Donnell JM
Neuropsychopharmacology; 2004 Aug; 29(8):1432-9. PubMed ID: 15114341
[TBL] [Abstract][Full Text] [Related]
12. Roflumilast, a Phosphodiesterase-4 Inhibitor, Ameliorates Sleep Deprivation-Induced Cognitive Dysfunction in C57BL/6J Mice.
Bhat A; Bishir M; Pandi-Perumal SR; Chang SL; Chidambaram SB
ACS Chem Neurosci; 2022 Jul; 13(13):1938-1947. PubMed ID: 35736514
[TBL] [Abstract][Full Text] [Related]
13. Roflumilast enhances cisplatin-sensitivity and reverses cisplatin-resistance of ovarian cancer cells via cAMP/PKA/CREB-FtMt signalling axis.
Gong S; Chen Y; Meng F; Zhang Y; Li C; Zhang G; Huan W; Wu F
Cell Prolif; 2018 Oct; 51(5):e12474. PubMed ID: 30069985
[TBL] [Abstract][Full Text] [Related]
14. A novel diol-derivative of chalcone produced by bioconversion, 3-(2,3-dihydroxyphenyl)-1-phenylpropan-1-one, activates PKA/MEK/ERK signaling and antagonizes Abeta-inhibition of the cascade in cultured rat CNS neurons.
Al Rahim M; Nakajima A; Misawa N; Shindo K; Adachi K; Shizuri Y; Ohizumi Y; Yamakuni T
Eur J Pharmacol; 2008 Dec; 600(1-3):10-7. PubMed ID: 18948095
[TBL] [Abstract][Full Text] [Related]
15. Roflumilast, a cAMP-Specific Phosphodiesterase-4 Inhibitor, Reduces Oxidative Stress and Improves Synapse Functions in Human Cortical Neurons Exposed to the Excitotoxin Quinolinic Acid.
Bhat A; Tan V; Heng B; Lovejoy DB; Sakharkar MK; Essa MM; Chidambaram SB; Guillemin GJ
ACS Chem Neurosci; 2020 Dec; 11(24):4405-4415. PubMed ID: 33261317
[TBL] [Abstract][Full Text] [Related]
16. Roscovitine, a CDK5 Inhibitor, Alleviates Sevoflurane-Induced Cognitive Dysfunction via Regulation Tau/GSK3β and ERK/PPARγ/CREB Signaling.
Liu J; Yang J; Xu Y; Guo G; Cai L; Wu H; Zhao Y; Zhang X
Cell Physiol Biochem; 2017; 44(2):423-435. PubMed ID: 29141245
[TBL] [Abstract][Full Text] [Related]
17. Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling pathways. A potential mechanism allowing for the coordinated regulation of PDE4D activity and expression in cells.
Liu H; Palmer D; Jimmo SL; Tilley DG; Dunkerley HA; Pang SC; Maurice DH
J Biol Chem; 2000 Aug; 275(34):26615-24. PubMed ID: 10851231
[TBL] [Abstract][Full Text] [Related]
18. Repeated exposure to sevoflurane in neonatal rats impairs cognition in adulthood via the PKA-CREB-BDNF signaling pathway.
Zhao J; Ren J; Liu S; Gong Y; Meng P; Tan H; Chen Y
Exp Ther Med; 2021 Dec; 22(6):1442. PubMed ID: 34721684
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of ERK/CREB signaling contributes to postoperative learning and memory dysfunction in neonatal rats.
Wang H; Ma G; Min J; Li J; Shan W; Zuo Z
J Mol Med (Berl); 2023 Mar; 101(3):265-278. PubMed ID: 36688960
[TBL] [Abstract][Full Text] [Related]
20. Lithium chloride ameliorates cognition dysfunction induced by sevoflurane anesthesia in rats.
Wang Y; An X; Zhang X; Liu J; Wang J; Yang Z
FEBS Open Bio; 2020 Feb; 10(2):251-258. PubMed ID: 31867790
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]