181 related articles for article (PubMed ID: 35776786)
1. Molecular mechanism of
Tang X; Zhang Y; Wang G; Zhang C; Wang F; Shi J; Zhang T; Ding J
Sci Adv; 2022 Jul; 8(26):eabn3868. PubMed ID: 35776786
[TBL] [Abstract][Full Text] [Related]
2. SAMTOR is an
Gu X; Orozco JM; Saxton RA; Condon KJ; Liu GY; Krawczyk PA; Scaria SM; Harper JW; Gygi SP; Sabatini DM
Science; 2017 Nov; 358(6364):813-818. PubMed ID: 29123071
[TBL] [Abstract][Full Text] [Related]
3. PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2.
Jiang C; Liu J; He S; Xu W; Huang R; Pan W; Li X; Dai X; Guo J; Zhang T; Inuzuka H; Wang P; Asara JM; Xiao J; Wei W
Cell Metab; 2023 Dec; 35(12):2183-2199.e7. PubMed ID: 38006878
[TBL] [Abstract][Full Text] [Related]
4. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Wolfson RL; Chantranupong L; Wyant GA; Gu X; Orozco JM; Shen K; Condon KJ; Petri S; Kedir J; Scaria SM; Abu-Remaileh M; Frankel WN; Sabatini DM
Nature; 2017 Mar; 543(7645):438-442. PubMed ID: 28199306
[TBL] [Abstract][Full Text] [Related]
5. Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level.
Chen S; Lu XT; He TT; Yishake D; Tan XY; Hou MJ; Luo Y; Long JA; Tang ZH; Zhong RH; Fang AP; Zhu HL
Mol Nutr Food Res; 2021 Aug; 65(15):e2100157. PubMed ID: 34061446
[TBL] [Abstract][Full Text] [Related]
6. Genetic Targeting of dSAMTOR, A Negative dTORC1 Regulator, during
Katarachia SA; Markaki SP; Velentzas AD; Stravopodis DJ
Int J Mol Sci; 2023 Jun; 24(11):. PubMed ID: 37298625
[TBL] [Abstract][Full Text] [Related]
7. An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway.
Liu GY; Jouandin P; Bahng RE; Perrimon N; Sabatini DM
Nat Commun; 2024 Mar; 15(1):2517. PubMed ID: 38514639
[TBL] [Abstract][Full Text] [Related]
8. SZT2 dictates GATOR control of mTORC1 signalling.
Peng M; Yin N; Li MO
Nature; 2017 Mar; 543(7645):433-437. PubMed ID: 28199315
[TBL] [Abstract][Full Text] [Related]
9. GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1.
Muller M; Bélanger J; Hadj-Aissa I; Zhang C; Sephton CF; Dutchak PA
Int J Mol Sci; 2024 Feb; 25(4):. PubMed ID: 38396745
[TBL] [Abstract][Full Text] [Related]
10. Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth.
Padi SKR; Singh N; Bearss JJ; Olive V; Song JH; Cardó-Vila M; Kraft AS; Okumura K
Proc Natl Acad Sci U S A; 2019 Oct; 116(41):20505-20510. PubMed ID: 31548394
[TBL] [Abstract][Full Text] [Related]
11. VWCE modulates amino acid-dependent mTOR signaling and coordinates with KICSTOR to recruit GATOR1 to the lysosomes.
Zhao T; Guan Y; Xu C; Wang D; Guan J; Liu Y
Nat Commun; 2023 Dec; 14(1):8464. PubMed ID: 38123554
[TBL] [Abstract][Full Text] [Related]
12. Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
Shen K; Valenstein ML; Gu X; Sabatini DM
J Biol Chem; 2019 Feb; 294(8):2970-2975. PubMed ID: 30651352
[TBL] [Abstract][Full Text] [Related]
13. Skeletal muscle-specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration.
Graber TG; Fry CS; Brightwell CR; Moro T; Maroto R; Bhattarai N; Porter C; Wakamiya M; Rasmussen BB
J Biol Chem; 2019 Mar; 294(11):4091-4102. PubMed ID: 30635399
[TBL] [Abstract][Full Text] [Related]
14. Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Egri SB; Ouch C; Chou HT; Yu Z; Song K; Xu C; Shen K
Mol Cell; 2022 May; 82(10):1836-1849.e5. PubMed ID: 35338845
[TBL] [Abstract][Full Text] [Related]
15. Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction.
Pal R; Palmieri M; Chaudhury A; Klisch TJ; di Ronza A; Neilson JR; Rodney GG; Sardiello M
Nat Commun; 2018 Oct; 9(1):4351. PubMed ID: 30341294
[TBL] [Abstract][Full Text] [Related]
16. mTORC1 stimulates cell growth through SAM synthesis and m
Villa E; Sahu U; O'Hara BP; Ali ES; Helmin KA; Asara JM; Gao P; Singer BD; Ben-Sahra I
Mol Cell; 2021 May; 81(10):2076-2093.e9. PubMed ID: 33756106
[TBL] [Abstract][Full Text] [Related]
17. Mechanism of Activation of Mechanistic Target of Rapamycin Complex 1 by Methionine.
Kitada M; Xu J; Ogura Y; Monno I; Koya D
Front Cell Dev Biol; 2020; 8():715. PubMed ID: 32850834
[TBL] [Abstract][Full Text] [Related]
18. Methionine Protects Mammary Cells against Oxidative Stress through Producing S-Adenosylmethionine to Maintain mTORC1 Signaling Activity.
Zhong H; Yuan P; Li Y; Batonon-Alavo D; Deschamps C; Feng B; Zhang X; Che L; Lin Y; Xu S; Li J; Zhuo Y; Tian G; Tang J; Jiang X; Huang L; Wu C; Wu D; Fang Z
Oxid Med Cell Longev; 2021; 2021():5550196. PubMed ID: 34336098
[TBL] [Abstract][Full Text] [Related]
19. Functional screening of GATOR1 complex variants reveals a role for mTORC1 deregulation in FCD and focal epilepsy.
Dawson RE; Nieto Guil AF; Robertson LJ; Piltz SG; Hughes JN; Thomas PQ
Neurobiol Dis; 2020 Feb; 134():104640. PubMed ID: 31639411
[TBL] [Abstract][Full Text] [Related]
20. Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.
Shin HR; Citron YR; Wang L; Tribouillard L; Goul CS; Stipp R; Sugasawa Y; Jain A; Samson N; Lim CY; Davis OB; Castaneda-Carpio D; Qian M; Nomura DK; Perera RM; Park E; Covey DF; Laplante M; Evers AS; Zoncu R
Science; 2022 Sep; 377(6612):1290-1298. PubMed ID: 36007018
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
