BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 35779635)

  • 1. Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1.
    Bandekar SJ; Chen CL; Ravala SK; Cash JN; Avramova LV; Zhalnina MV; Gutkind JS; Li S; Tesmer JJG
    J Biol Chem; 2022 Aug; 298(8):102209. PubMed ID: 35779635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.
    Debreceni B; Gao Y; Guo F; Zhu K; Jia B; Zheng Y
    J Biol Chem; 2004 Jan; 279(5):3777-86. PubMed ID: 14597635
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin.
    Bellanger JM; Astier C; Sardet C; Ohta Y; Stossel TP; Debant A
    Nat Cell Biol; 2000 Dec; 2(12):888-92. PubMed ID: 11146652
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Role of the multifunctional Trio protein in the control of the Rac1 and RhoA gtpase signaling pathways].
    Bellanger JM; Zugasti O; Lazaro JB; Diriong S; Lamb N; Sardet C; Debant A
    C R Seances Soc Biol Fil; 1998; 192(2):367-74. PubMed ID: 9759378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
    Bandekar SJ; Arang N; Tully ES; Tang BA; Barton BL; Li S; Gutkind JS; Tesmer JJG
    Sci Signal; 2019 Feb; 12(569):. PubMed ID: 30783010
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evolution of the Rho guanine nucleotide exchange factors Kalirin and Trio and their gene expression in Xenopus development.
    Kratzer MC; England L; Apel D; Hassel M; Borchers A
    Gene Expr Patterns; 2019 Jun; 32():18-27. PubMed ID: 30844509
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activation.
    Chhatriwala MK; Betts L; Worthylake DK; Sondek J
    J Mol Biol; 2007 May; 368(5):1307-20. PubMed ID: 17391702
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.
    Xu Z; Gakhar L; Bain FE; Spies M; Fuentes EJ
    J Biol Chem; 2017 Oct; 292(43):17777-17793. PubMed ID: 28882897
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.
    van Rijssel J; Hoogenboezem M; Wester L; Hordijk PL; Van Buul JD
    PLoS One; 2012; 7(1):e29912. PubMed ID: 22238672
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The many faces of the guanine-nucleotide exchange factor trio.
    van Rijssel J; van Buul JD
    Cell Adh Migr; 2012; 6(6):482-7. PubMed ID: 23076143
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.
    Rojas RJ; Yohe ME; Gershburg S; Kawano T; Kozasa T; Sondek J
    J Biol Chem; 2007 Oct; 282(40):29201-10. PubMed ID: 17606614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel intermediate of Rac GTPase activation by guanine nucleotide exchange factor.
    Zhang B; Yang L; Zheng Y
    Biochem Biophys Res Commun; 2005 Jun; 331(2):413-21. PubMed ID: 15850775
    [TBL] [Abstract][Full Text] [Related]  

  • 13. betaPak-interacting exchange factor-mediated Rac1 activation requires smgGDS guanine nucleotide exchange factor in basic fibroblast growth factor-induced neurite outgrowth.
    Shin EY; Lee CS; Cho TG; Kim YG; Song S; Juhnn YS; Park SC; Manser E; Kim EG
    J Biol Chem; 2006 Nov; 281(47):35954-64. PubMed ID: 16954223
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
    Wang L; Zhu K; Zheng Y
    Biochemistry; 2004 Nov; 43(46):14584-93. PubMed ID: 15544329
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.
    Debant A; Serra-Pagès C; Seipel K; O'Brien S; Tang M; Park SH; Streuli M
    Proc Natl Acad Sci U S A; 1996 May; 93(11):5466-71. PubMed ID: 8643598
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Different regulation of the Trio Dbl-Homology domains by their associated PH domains.
    Bellanger JM; Estrach S; Schmidt S; Briançon-Marjollet A; Zugasti O; Fromont S; Debant A
    Biol Cell; 2003 Dec; 95(9):625-34. PubMed ID: 14720465
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinct functions of Trio GEF domains in axon outgrowth of cerebellar granule neurons.
    Tao T; Sun J; Peng Y; Wang P; Chen X; Zhao W; Li Y; Wei L; Wang W; Zheng Y; Wang Y; Zhang X; Zhu MS
    J Genet Genomics; 2019 Feb; 46(2):87-96. PubMed ID: 30850274
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The two guanine nucleotide exchange factor domains of Trio link the Rac1 and the RhoA pathways in vivo.
    Bellanger JM; Lazaro JB; Diriong S; Fernandez A; Lamb N; Debant A
    Oncogene; 1998 Jan; 16(2):147-52. PubMed ID: 9464532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids.
    Skowronek KR; Guo F; Zheng Y; Nassar N
    J Biol Chem; 2004 Sep; 279(36):37895-907. PubMed ID: 15199069
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled.
    Kratzer MC; Becker SFS; Grund A; Merks A; Harnoš J; Bryja V; Giehl K; Kashef J; Borchers A
    Development; 2020 May; 147(10):. PubMed ID: 32366678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.