198 related articles for article (PubMed ID: 35786658)
1. 3-Hydroxyacyl-CoA and Alcohol Dehydrogenase Activities of Mitochondrial Type 10 17β-Hydroxysteroid Dehydrogenase in Neurodegeneration Study.
He XY; Dobkin C; Brown WT; Yang SY
J Alzheimers Dis; 2022; 88(4):1487-1497. PubMed ID: 35786658
[TBL] [Abstract][Full Text] [Related]
2. Infantile Neurodegeneration Results from Mutants of 17β-Hydroxysteroid Dehydrogenase Type 10 Rather Than Aβ-Binding Alcohol Dehydrogenase.
He XY; Dobkin C; Brown WT; Yang SY
Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37239833
[TBL] [Abstract][Full Text] [Related]
3. Roles of Mitochondrial 17β-Hydroxysteroid Dehydrogenase Type 10 in Alzheimer's Disease.
He XY; Isaacs C; Yang SY
J Alzheimers Dis; 2018; 62(2):665-673. PubMed ID: 29480196
[TBL] [Abstract][Full Text] [Related]
4. Involvement of Type 10 17β-Hydroxysteroid Dehydrogenase in the Pathogenesis of Infantile Neurodegeneration and Alzheimer's Disease.
He XY; Frackowiak J; Dobkin C; Brown WT; Yang SY
Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139430
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.
Hroch L; Benek O; Guest P; Aitken L; Soukup O; Janockova J; Musil K; Dohnal V; Dolezal R; Kuca K; Smith TK; Gunn-Moore F; Musilek K
Bioorg Med Chem Lett; 2016 Aug; 26(15):3675-8. PubMed ID: 27287370
[TBL] [Abstract][Full Text] [Related]
6. Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders.
Yang SY; He XY; Isaacs C; Dobkin C; Miller D; Philipp M
J Steroid Biochem Mol Biol; 2014 Sep; 143():460-72. PubMed ID: 25007702
[TBL] [Abstract][Full Text] [Related]
7. Comparative evolutionary genomics of the HADH2 gene encoding Abeta-binding alcohol dehydrogenase/17beta-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10).
Marques AT; Antunes A; Fernandes PA; Ramos MJ
BMC Genomics; 2006 Aug; 7():202. PubMed ID: 16899120
[TBL] [Abstract][Full Text] [Related]
8. Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment.
Aitken L; Benek O; McKelvie BE; Hughes RE; Hroch L; Schmidt M; Major LL; Vinklarova L; Kuca K; Smith TK; Musilek K; Gunn-Moore FJ
Molecules; 2019 Jul; 24(15):. PubMed ID: 31362457
[No Abstract] [Full Text] [Related]
9. Recognition of structurally diverse substrates by type II 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD).
Powell AJ; Read JA; Banfield MJ; Gunn-Moore F; Yan SD; Lustbader J; Stern AR; Stern DM; Brady RL
J Mol Biol; 2000 Oct; 303(2):311-27. PubMed ID: 11023795
[TBL] [Abstract][Full Text] [Related]
10. ABAD/17β-HSD10 reduction contributes to the protective mechanism of huperzine a on the cerebral mitochondrial function in APP/PS1 mice.
Xiao X; Chen Q; Zhu X; Wang Y
Neurobiol Aging; 2019 Sep; 81():77-87. PubMed ID: 31252207
[TBL] [Abstract][Full Text] [Related]
11. Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aβ in a Neuroinflammatory Alzheimer's Disease Mouse Model.
Zakaria A; Hamdi N; Abdel-Kader RM
Mol Neurobiol; 2016 Mar; 53(2):1220-1228. PubMed ID: 25601181
[TBL] [Abstract][Full Text] [Related]
12. Intrinsic alcohol dehydrogenase and hydroxysteroid dehydrogenase activities of human mitochondrial short-chain L-3-hydroxyacyl-CoA dehydrogenase.
He XY; Yang YZ; Schulz H; Yang SY
Biochem J; 2000 Jan; 345 Pt 1(Pt 1):139-43. PubMed ID: 10600649
[TBL] [Abstract][Full Text] [Related]
13. Multiple functions of type 10 17beta-hydroxysteroid dehydrogenase.
Yang SY; He XY; Schulz H
Trends Endocrinol Metab; 2005; 16(4):167-75. PubMed ID: 15860413
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.
Hroch L; Guest P; Benek O; Soukup O; Janockova J; Dolezal R; Kuca K; Aitken L; Smith TK; Gunn-Moore F; Zala D; Ramsay RR; Musilek K
Bioorg Med Chem; 2017 Feb; 25(3):1143-1152. PubMed ID: 28082069
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics.
Kissinger CR; Rejto PA; Pelletier LA; Thomson JA; Showalter RE; Abreo MA; Agree CS; Margosiak S; Meng JJ; Aust RM; Vanderpool D; Li B; Tempczyk-Russell A; Villafranca JE
J Mol Biol; 2004 Sep; 342(3):943-52. PubMed ID: 15342248
[TBL] [Abstract][Full Text] [Related]
16. Friend or enemy? Review of 17β-HSD10 and its role in human health or disease.
Vinklarova L; Schmidt M; Benek O; Kuca K; Gunn-Moore F; Musilek K
J Neurochem; 2020 Nov; 155(3):231-249. PubMed ID: 32306391
[TBL] [Abstract][Full Text] [Related]
17. 6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.
Benek O; Hroch L; Aitken L; Dolezal R; Guest P; Benkova M; Soukup O; Musil K; Kuca K; Smith TK; Gunn-Moore F; Musilek K
Med Chem; 2017 Jan; ():. PubMed ID: 28067167
[TBL] [Abstract][Full Text] [Related]
18. Amyloid-Binding Alcohol Dehydrogenase (ABAD) Inhibitors for the Treatment of Alzheimer's Disease.
Morsy A; Trippier PC
J Med Chem; 2019 May; 62(9):4252-4264. PubMed ID: 30444369
[TBL] [Abstract][Full Text] [Related]
19. Hydroxysteroid (17β) dehydrogenase X in human health and disease.
Yang SY; He XY; Miller D
Mol Cell Endocrinol; 2011 Aug; 343(1-2):1-6. PubMed ID: 21708223
[TBL] [Abstract][Full Text] [Related]
20. Levels of 17β-Hydroxysteroid Dehydrogenase Type 10 in Cerebrospinal Fluid of People with Mild Cognitive Impairment and Various Types of Dementias.
Kristofikova Z; Ricny J; Vyhnalek M; Hort J; Laczo J; Sirova J; Klaschka J; Ripova D
J Alzheimers Dis; 2015; 48(1):105-14. PubMed ID: 26401932
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]