These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 35804016)

  • 1. PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma.
    Thirusangu P; Ray U; Sarkar Bhattacharya S; Oien DB; Jin L; Staub J; Kannan N; Molina JR; Shridhar V
    Oncogene; 2022 Aug; 41(33):4003-4017. PubMed ID: 35804016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM.
    Sarkar Bhattacharya S; Thirusangu P; Jin L; Staub J; Shridhar V; Molina JR
    Br J Cancer; 2022 Oct; 127(7):1352-1364. PubMed ID: 35794237
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer.
    Xiao Y; Jin L; Deng C; Guan Y; Kalogera E; Ray U; Thirusangu P; Staub J; Sarkar Bhattacharya S; Xu H; Fang X; Shridhar V
    Oncogene; 2021 Feb; 40(8):1409-1424. PubMed ID: 33420377
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers.
    Mondal S; Roy D; Sarkar Bhattacharya S; Jin L; Jung D; Zhang S; Kalogera E; Staub J; Wang Y; Xuyang W; Khurana A; Chien J; Telang S; Chesney J; Tapolsky G; Petras D; Shridhar V
    Int J Cancer; 2019 Jan; 144(1):178-189. PubMed ID: 30226266
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 activity in response to EGFR signaling contributes to non-small cell lung cancer cell survival.
    Lypova N; Telang S; Chesney J; Imbert-Fernandez Y
    J Biol Chem; 2019 Jul; 294(27):10530-10543. PubMed ID: 31126985
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy.
    Li X; Liu J; Qian L; Ke H; Yao C; Tian W; Liu Y; Zhang J
    Mol Cell Biochem; 2018 Aug; 445(1-2):123-134. PubMed ID: 29327288
    [TBL] [Abstract][Full Text] [Related]  

  • 7. YAP promotes ocular neovascularization by modifying PFKFB3-driven endothelial glycolysis.
    Feng Y; Zou R; Zhang X; Shen M; Chen X; Wang J; Niu W; Yuan Y; Yuan F
    Angiogenesis; 2021 Aug; 24(3):489-504. PubMed ID: 33400016
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PFKFB3 Regulates Chemoresistance, Metastasis and Stemness
    Jiang YX; Siu MKY; Wang JJ; Leung THY; Chan DW; Cheung ANY; Ngan HYS; Chan KKL
    Front Oncol; 2022; 12():748403. PubMed ID: 35155224
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma.
    Li J; Zhang S; Liao D; Zhang Q; Chen C; Yang X; Jiang D; Pang J
    BMC Cancer; 2022 Jan; 22(1):83. PubMed ID: 35057732
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells.
    Rodríguez-García A; Samsó P; Fontova P; Simon-Molas H; Manzano A; Castaño E; Rosa JL; Martinez-Outshoorn U; Ventura F; Navarro-Sabaté À; Bartrons R
    FEBS J; 2017 Oct; 284(20):3437-3454. PubMed ID: 28834297
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HOXD9 contributes to the Warburg effect and tumor metastasis in non-small cell lung cancer via transcriptional activation of PFKFB3.
    Wan K; Shao J; Liu X; Cai Y; Xu Y; Li L; Xiong L; Liang S
    Exp Cell Res; 2023 Jun; 427(1):113583. PubMed ID: 37004946
    [TBL] [Abstract][Full Text] [Related]  

  • 12. KLF9 (Kruppel Like Factor 9) induced PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3) downregulation inhibits the proliferation, metastasis and aerobic glycolysis of cutaneous squamous cell carcinoma cells.
    Xing J; Jia Z; Xu Y; Chen M; Yang Z; Chen Y; Han Y
    Bioengineered; 2021 Dec; 12(1):7563-7576. PubMed ID: 34612136
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses.
    Sarkar Bhattacharya S; Thirusangu P; Jin L; Roy D; Jung D; Xiao Y; Staub J; Roy B; Molina JR; Shridhar V
    Cell Death Dis; 2019 Sep; 10(10):725. PubMed ID: 31562297
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reactive Oxygen Species Drive Proliferation in Acute Myeloid Leukemia via the Glycolytic Regulator PFKFB3.
    Robinson AJ; Hopkins GL; Rastogi N; Hodges M; Doyle M; Davies S; Hole PS; Omidvar N; Darley RL; Tonks A
    Cancer Res; 2020 Mar; 80(5):937-949. PubMed ID: 31862780
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.
    Clem B; Telang S; Clem A; Yalcin A; Meier J; Simmons A; Rasku MA; Arumugam S; Dean WL; Eaton J; Lane A; Trent JO; Chesney J
    Mol Cancer Ther; 2008 Jan; 7(1):110-20. PubMed ID: 18202014
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A non-metabolic function of hexokinase 2 in small cell lung cancer: promotes cancer cell stemness by increasing USP11-mediated CD133 stability.
    Wang J; Shao F; Yang Y; Wang W; Yang X; Li R; Cheng H; Sun S; Feng X; Gao Y; He J; Lu Z
    Cancer Commun (Lond); 2022 Oct; 42(10):1008-1027. PubMed ID: 35975322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of glycolytic activator PFKFB3 suppresses tumor growth and induces tumor vessel normalization in hepatocellular carcinoma.
    Matsumoto K; Noda T; Kobayashi S; Sakano Y; Yokota Y; Iwagami Y; Yamada D; Tomimaru Y; Akita H; Gotoh K; Takeda Y; Tanemura M; Umeshita K; Doki Y; Eguchi H
    Cancer Lett; 2021 Mar; 500():29-40. PubMed ID: 33307155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination of 3PO analog PFK15 and siPFKL efficiently suppresses the migration, colony formation ability, and PFK-1 activity of triple-negative breast cancers by reducing the glycolysis.
    Kashyap A; Umar SM; Dev J R A; Mathur SR; Gogia A; Batra A; Deo SVS; Prasad CP
    J Cell Biochem; 2023 Sep; 124(9):1259-1272. PubMed ID: 37450687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma.
    Yang K; Qiu T; Zhou J; Gong X; Zhang X; Lan Y; Zhang Z; Ji Y
    J Transl Med; 2023 Feb; 21(1):85. PubMed ID: 36740704
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer.
    Bando H; Atsumi T; Nishio T; Niwa H; Mishima S; Shimizu C; Yoshioka N; Bucala R; Koike T
    Clin Cancer Res; 2005 Aug; 11(16):5784-92. PubMed ID: 16115917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.