BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 35807552)

  • 1. Conversion of the Native N-Terminal Domain of TDP-43 into a Monomeric Alternative Fold with Lower Aggregation Propensity.
    Moretti M; Marzi I; Cantarutti C; Vivoli Vega M; Mandaliti W; Mimmi MC; Bemporad F; Corazza A; Chiti F
    Molecules; 2022 Jul; 27(13):. PubMed ID: 35807552
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
    Mompeán M; Romano V; Pantoja-Uceda D; Stuani C; Baralle FE; Buratti E; Laurents DV
    J Biol Chem; 2017 Jul; 292(28):11992-12006. PubMed ID: 28566288
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insight into the Folding and Dimerization Mechanisms of the N-Terminal Domain from Human TDP-43.
    Vivoli-Vega M; Guri P; Chiti F; Bemporad F
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32872449
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biophysical characterization of full-length TAR DNA-binding protein (TDP-43) phase separation.
    Staderini T; Bigi A; Mongiello D; Cecchi C; Chiti F
    Protein Sci; 2022 Dec; 31(12):e4509. PubMed ID: 36371546
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
    Baloh RH
    FEBS J; 2011 Oct; 278(19):3539-49. PubMed ID: 21777387
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
    Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
    Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative analysis of thermal unfolding simulations of RNA recognition motifs (RRMs) of TAR DNA-binding protein 43 (TDP-43).
    Prakash A; Kumar V; Meena NK; Hassan MI; Lynn AM
    J Biomol Struct Dyn; 2019 Jan; 37(1):178-194. PubMed ID: 29279008
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43.
    Watanabe S; Inami H; Oiwa K; Murata Y; Sakai S; Komine O; Sobue A; Iguchi Y; Katsuno M; Yamanaka K
    Cell Death Dis; 2020 Oct; 11(10):909. PubMed ID: 33097688
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis.
    Tan RH; Yang Y; Kim WS; Dobson-Stone C; Kwok JB; Kiernan MC; Halliday GM
    Acta Neuropathol Commun; 2017 Oct; 5(1):76. PubMed ID: 29078806
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
    Collins M; Riascos D; Kovalik T; An J; Krupa K; Krupa K; Hood BL; Conrads TP; Renton AE; Traynor BJ; Bowser R
    Acta Neuropathol; 2012 Nov; 124(5):717-32. PubMed ID: 22993125
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration.
    Bosque PJ; Boyer PJ; Mishra P
    PLoS One; 2013; 8(5):e62301. PubMed ID: 23704877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.
    Wang A; Conicella AE; Schmidt HB; Martin EW; Rhoads SN; Reeb AN; Nourse A; Ramirez Montero D; Ryan VH; Rohatgi R; Shewmaker F; Naik MT; Mittag T; Ayala YM; Fawzi NL
    EMBO J; 2018 Mar; 37(5):. PubMed ID: 29438978
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).
    Bentmann E; Neumann M; Tahirovic S; Rodde R; Dormann D; Haass C
    J Biol Chem; 2012 Jun; 287(27):23079-94. PubMed ID: 22563080
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Importin α/β and the tug of war to keep TDP-43 in solution: quo vadis?
    Doll SG; Cingolani G
    Bioessays; 2022 Dec; 44(12):e2200181. PubMed ID: 36253101
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations.
    Maekawa S; Leigh PN; King A; Jones E; Steele JC; Bodi I; Shaw CE; Hortobagyi T; Al-Sarraj S
    Neuropathology; 2009 Dec; 29(6):672-83. PubMed ID: 19496940
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing.
    Che MX; Jiang YJ; Xie YY; Jiang LL; Hu HY
    FASEB J; 2011 Jul; 25(7):2344-53. PubMed ID: 21450909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.
    Wang YT; Kuo PH; Chiang CH; Liang JR; Chen YR; Wang S; Shen JC; Yuan HS
    J Biol Chem; 2013 Mar; 288(13):9049-57. PubMed ID: 23372158
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Folding of the RNA recognition motif (RRM) domains of the amyotrophic lateral sclerosis (ALS)-linked protein TDP-43 reveals an intermediate state.
    Mackness BC; Tran MT; McClain SP; Matthews CR; Zitzewitz JA
    J Biol Chem; 2014 Mar; 289(12):8264-76. PubMed ID: 24497641
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Igaz LM; Kwong LK; Xu Y; Truax AC; Uryu K; Neumann M; Clark CM; Elman LB; Miller BL; Grossman M; McCluskey LF; Trojanowski JQ; Lee VM
    Am J Pathol; 2008 Jul; 173(1):182-94. PubMed ID: 18535185
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation.
    Zhang YJ; Caulfield T; Xu YF; Gendron TF; Hubbard J; Stetler C; Sasaguri H; Whitelaw EC; Cai S; Lee WC; Petrucelli L
    Hum Mol Genet; 2013 Aug; 22(15):3112-22. PubMed ID: 23575225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.