132 related articles for article (PubMed ID: 35810594)
1. RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia.
Pham LT; Peng H; Ueno M; Kohno S; Kasada A; Hosomichi K; Sato T; Kurayoshi K; Kobayashi M; Tadokoro Y; Kasahara A; Shoulkamy MI; Xiao B; Worley PF; Takahashi C; Tajima A; Hirao A
Biochem Biophys Res Commun; 2022 Sep; 621():74-79. PubMed ID: 35810594
[TBL] [Abstract][Full Text] [Related]
2. MicroRNA-199a-5p Induced Autophagy and Inhibits the Pathogenesis of Ankylosing Spondylitis by Modulating the mTOR Signaling via Directly Targeting Ras Homolog Enriched in Brain (Rheb).
Wang Y; Luo J; Wang X; Yang B; Cui L
Cell Physiol Biochem; 2017; 42(6):2481-2491. PubMed ID: 28848090
[TBL] [Abstract][Full Text] [Related]
3. Rheb regulates nuclear mTORC1 activity independent of farnesylation.
Zhong Y; Zhou X; Guan KL; Zhang J
Cell Chem Biol; 2022 Jun; 29(6):1037-1045.e4. PubMed ID: 35294906
[TBL] [Abstract][Full Text] [Related]
4. Persistent Rheb-induced mTORC1 activation in spinal cord neurons induces hypersensitivity in neuropathic pain.
Ma X; Du W; Wang W; Luo L; Huang M; Wang H; Lin R; Li Z; Shi H; Yuan T; Jiang W; Worley PF; Xu T
Cell Death Dis; 2020 Sep; 11(9):747. PubMed ID: 32920594
[TBL] [Abstract][Full Text] [Related]
5. Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells.
Peng H; Kasada A; Ueno M; Hoshii T; Tadokoro Y; Nomura N; Ito C; Takase Y; Vu HT; Kobayashi M; Xiao B; Worley PF; Hirao A
Biochem Biophys Res Commun; 2018 Jan; 495(1):1129-1135. PubMed ID: 29175333
[TBL] [Abstract][Full Text] [Related]
6. CBAP modulates Akt-dependent TSC2 phosphorylation to promote Rheb-mTORC1 signaling and growth of T-cell acute lymphoblastic leukemia.
Chiang YJ; Liao WT; Ho KC; Wang SH; Chen YG; Ho CL; Huang SF; Shih LY; Yang-Yen HF; Yen JJ
Oncogene; 2019 Feb; 38(9):1432-1447. PubMed ID: 30266989
[TBL] [Abstract][Full Text] [Related]
7. Circadian Rheb oscillation alters the dynamics of hepatic mTORC1 activity and mitochondrial morphology.
Yuan Q; Chen M; Yang W; Xiao B
FEBS Lett; 2021 Feb; 595(3):360-369. PubMed ID: 33247956
[TBL] [Abstract][Full Text] [Related]
8. mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB.
Walton ZE; Brooks RC; Dang CV
Bioessays; 2019 Jul; 41(7):e1800265. PubMed ID: 31157925
[TBL] [Abstract][Full Text] [Related]
9. TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling.
Xie J; De Poi SP; Humphrey SJ; Hein LK; Bruning JB; Pan W; Selth LA; Sargeant TJ; Proud CG
Cell Mol Life Sci; 2021 Apr; 78(8):4035-4052. PubMed ID: 33834258
[TBL] [Abstract][Full Text] [Related]
10. Silencing of RHEB inhibits cell proliferation and promotes apoptosis in colorectal cancer cells via inhibition of the mTOR signaling pathway.
Tian Y; Shen L; Li F; Yang J; Wan X; Ouyang M
J Cell Physiol; 2020 Jan; 235(1):442-453. PubMed ID: 31332784
[TBL] [Abstract][Full Text] [Related]
11. Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment.
Angarola B; Ferguson SM
Mol Biol Cell; 2019 Oct; 30(22):2750-2760. PubMed ID: 31532697
[TBL] [Abstract][Full Text] [Related]
12. PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
Liu Z; Chen X; Wang Y; Peng H; Wang Y; Jing Y; Zhang H
J Biol Chem; 2014 Oct; 289(43):29739-49. PubMed ID: 25164809
[TBL] [Abstract][Full Text] [Related]
13. Licochalcone A restrains microphthalmia-associated transcription factor expression and growth by activating autophagy in melanoma cells via miR-142-3p/Rheb/mTOR pathway.
Zhang Y; Gao M; Chen L; Zhou L; Bian S; Lv Y
Phytother Res; 2020 Feb; 34(2):349-358. PubMed ID: 31793097
[TBL] [Abstract][Full Text] [Related]
14. ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.
Blackwood EA; Hofmann C; Santo Domingo M; Bilal AS; Sarakki A; Stauffer W; Arrieta A; Thuerauf DJ; Kolkhorst FW; Müller OJ; Jakobi T; Dieterich C; Katus HA; Doroudgar S; Glembotski CC
Circ Res; 2019 Jan; 124(1):79-93. PubMed ID: 30582446
[TBL] [Abstract][Full Text] [Related]
15. Ubiquitination of Rheb governs growth factor-induced mTORC1 activation.
Deng L; Chen L; Zhao L; Xu Y; Peng X; Wang X; Ding L; Jin J; Teng H; Wang Y; Pan W; Yu F; Liao L; Li L; Ge X; Wang P
Cell Res; 2019 Feb; 29(2):136-150. PubMed ID: 30514904
[TBL] [Abstract][Full Text] [Related]
16. Rheb may complex with RASSF1A to coordinate Hippo and TOR signaling.
Nelson N; Clark GJ
Oncotarget; 2016 Jun; 7(23):33821-31. PubMed ID: 27034171
[TBL] [Abstract][Full Text] [Related]
17. Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Mavrakis KJ; Zhu H; Silva RL; Mills JR; Teruya-Feldstein J; Lowe SW; Tam W; Pelletier J; Wendel HG
Genes Dev; 2008 Aug; 22(16):2178-88. PubMed ID: 18708578
[TBL] [Abstract][Full Text] [Related]
18. A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II.
Zhao S; Li Z; Zhang M; Zhang L; Zheng H; Ning J; Wang Y; Wang F; Zhang X; Gan H; Wang Y; Zhang X; Luo H; Bu G; Xu H; Yao Y; Zhang YW
Exp Mol Med; 2019 Jul; 51(7):1-11. PubMed ID: 31337748
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays.
Shams R; Ito Y; Miyatake H
Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445471
[TBL] [Abstract][Full Text] [Related]
20. Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period.
Tamai T; Yamaguchi O; Hikoso S; Takeda T; Taneike M; Oka T; Oyabu J; Murakawa T; Nakayama H; Uno Y; Horie K; Nishida K; Sonenberg N; Shah AM; Takeda J; Komuro I; Otsu K
J Biol Chem; 2013 Apr; 288(14):10176-10187. PubMed ID: 23426372
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
