These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin. Orwig SD; Perry CW; Kim LY; Turnage KC; Zhang R; Vollrath D; Schmidt-Krey I; Lieberman RL J Mol Biol; 2012 Aug; 421(2-3):242-55. PubMed ID: 22197377 [TBL] [Abstract][Full Text] [Related]
6. The glaucoma-associated olfactomedin domain of myocilin is a novel calcium binding protein. Donegan RK; Hill SE; Turnage KC; Orwig SD; Lieberman RL J Biol Chem; 2012 Dec; 287(52):43370-7. PubMed ID: 23129764 [TBL] [Abstract][Full Text] [Related]
7. The glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequence. Hill SE; Donegan RK; Lieberman RL J Mol Biol; 2014 Feb; 426(4):921-35. PubMed ID: 24333014 [TBL] [Abstract][Full Text] [Related]
8. Functional analysis of the glaucoma-causing TIGR/myocilin protein: integrity of amino-terminal coiled-coil regions and olfactomedin homology domain is essential for extracellular adhesion and secretion. Gobeil S; Letartre L; Raymond V Exp Eye Res; 2006 Jun; 82(6):1017-29. PubMed ID: 16466712 [TBL] [Abstract][Full Text] [Related]
9. Temperature sensitive secretion of mutant myocilins. Vollrath D; Liu Y Exp Eye Res; 2006 Jun; 82(6):1030-6. PubMed ID: 16297911 [TBL] [Abstract][Full Text] [Related]
10. Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork. Kasetti RB; Phan TN; Millar JC; Zode GS Invest Ophthalmol Vis Sci; 2016 Nov; 57(14):6058-6069. PubMed ID: 27820874 [TBL] [Abstract][Full Text] [Related]
11. Different Grp94 components interact transiently with the myocilin olfactomedin domain in vitro to enhance or retard its amyloid aggregation. Huard DJE; Jonke AP; Torres MP; Lieberman RL Sci Rep; 2019 Sep; 9(1):12769. PubMed ID: 31484937 [TBL] [Abstract][Full Text] [Related]
12. Differential Misfolding Properties of Glaucoma-Associated Olfactomedin Domains from Humans and Mice. Patterson-Orazem AC; Hill SE; Wang Y; Dominic IM; Hall CK; Lieberman RL Biochemistry; 2019 Apr; 58(13):1718-1727. PubMed ID: 30802039 [TBL] [Abstract][Full Text] [Related]
13. Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma. Liu Y; Vollrath D Hum Mol Genet; 2004 Jun; 13(11):1193-204. PubMed ID: 15069026 [TBL] [Abstract][Full Text] [Related]
14. The effects of myocilin expression on functionally relevant trabecular meshwork genes: a mini-review. Borrás T J Ocul Pharmacol Ther; 2014; 30(2-3):202-12. PubMed ID: 24564495 [TBL] [Abstract][Full Text] [Related]
15. Heterozygous expression of myocilin glaucoma mutants increases secretion of the mutant forms and reduces extracellular processed myocilin. Aroca-Aguilar JD; Sánchez-Sánchez F; Martínez-Redondo F; Coca-Prados M; Escribano J Mol Vis; 2008; 14():2097-108. PubMed ID: 19023451 [TBL] [Abstract][Full Text] [Related]
16. Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma. Yam GH; Gaplovska-Kysela K; Zuber C; Roth J Am J Pathol; 2007 Jan; 170(1):100-9. PubMed ID: 17200186 [TBL] [Abstract][Full Text] [Related]
17. Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis. Yam GH; Gaplovska-Kysela K; Zuber C; Roth J Invest Ophthalmol Vis Sci; 2007 Apr; 48(4):1683-90. PubMed ID: 17389500 [TBL] [Abstract][Full Text] [Related]