BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 35840668)

  • 1. MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state.
    Zhang WC; Skiados N; Aftab F; Moreno C; Silva L; Corbilla PJA; Asara JM; Hata AN; Slack FJ
    Cancer Gene Ther; 2022 Dec; 29(12):1878-1894. PubMed ID: 35840668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and biochemical characterization of human adenylosuccinate lyase (ADSL) and the R303C ADSL deficiency-associated mutation.
    Ray SP; Deaton MK; Capodagli GC; Calkins LA; Sawle L; Ghosh K; Patterson D; Pegan SD
    Biochemistry; 2012 Aug; 51(33):6701-13. PubMed ID: 22812634
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Purine Homeostasis Is Necessary for Developmental Timing, Germline Maintenance and Muscle Integrity in
    Marsac R; Pinson B; Saint-Marc C; Olmedo M; Artal-Sanz M; Daignan-Fornier B; Gomes JE
    Genetics; 2019 Apr; 211(4):1297-1313. PubMed ID: 30700528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular characterization of the AdeI mutant of Chinese hamster ovary cells: a cellular model of adenylosuccinate lyase deficiency.
    Vliet LK; Wilkinson TG; Duval N; Vacano G; Graham C; Zikánová M; Skopova V; Baresova V; Hnízda A; Kmoch S; Patterson D
    Mol Genet Metab; 2011 Jan; 102(1):61-8. PubMed ID: 20884265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function.
    Jiang T; Sánchez-Rivera FJ; Soto-Feliciano YM; Yang Q; Song CQ; Bhuatkar A; Haynes CM; Hemann MT; Xue W
    Hepatology; 2021 Jul; 74(1):233-247. PubMed ID: 33336367
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
    Romanello L; Serrão VHB; Torini JR; Bird LE; Nettleship JE; Rada H; Reddivari Y; Owens RJ; DeMarco R; Brandão-Neto J; Pereira HD
    Mol Biochem Parasitol; 2017 Jun; 214():27-35. PubMed ID: 28347672
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
    Taha-Mehlitz S; Bianco G; Coto-Llerena M; Kancherla V; Bantug GR; Gallon J; Ercan C; Panebianco F; Eppenberger-Castori S; von Strauss M; Staubli S; Bolli M; Peterli R; Matter MS; Terracciano LM; von Flüe M; Ng CKY; Soysal SD; Kollmar O; Piscuoglio S
    Theranostics; 2021; 11(9):4011-4029. PubMed ID: 33754045
    [No Abstract]   [Full Text] [Related]  

  • 8. Pathway-specific effects of ADSL deficiency on neurodevelopment.
    Dutto I; Gerhards J; Herrera A; Souckova O; Škopová V; Smak JA; Junza A; Yanes O; Boeckx C; Burkhalter MD; Zikánová M; Pons S; Philipp M; Lüders J; Stracker TH
    Elife; 2022 Feb; 11():. PubMed ID: 35133277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Correction to: MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state.
    Zhang WC; Skiados N; Aftab F; Moreno C; Silva L; Corbilla PJA; Asara JM; Hata AN; Slack FJ
    Cancer Gene Ther; 2022 Dec; 29(12):2013. PubMed ID: 36002769
    [No Abstract]   [Full Text] [Related]  

  • 10. Inherent properties of adenylosuccinate lyase could explain S-Ado/SAICAr ratio due to homozygous R426H and R303C mutations.
    Ray SP; Duval N; Wilkinson TG; Shaheen SE; Ghosh K; Patterson D
    Biochim Biophys Acta; 2013 Aug; 1834(8):1545-53. PubMed ID: 23714113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disorders of purine biosynthesis metabolism.
    Dewulf JP; Marie S; Nassogne MC
    Mol Genet Metab; 2022 Jul; 136(3):190-198. PubMed ID: 34998670
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinical, biochemical and molecular genetic correlations in adenylosuccinate lyase deficiency.
    Race V; Marie S; Vincent MF; Van den Berghe G
    Hum Mol Genet; 2000 Sep; 9(14):2159-65. PubMed ID: 10958654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum.
    Bulusu V; Srinivasan B; Bopanna MP; Balaram H
    Biochim Biophys Acta; 2009 Apr; 1794(4):642-54. PubMed ID: 19111634
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation of a nuclear respiratory factor 2 binding site in the 5' untranslated region of the ADSL gene in three patients with adenylosuccinate lyase deficiency.
    Marie S; Race V; Nassogne MC; Vincent MF; Van den Berghe G
    Am J Hum Genet; 2002 Jul; 71(1):14-21. PubMed ID: 12016589
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.
    Duval N; Luhrs K; Wilkinson TG; Baresova V; Skopova V; Kmoch S; Vacano GN; Zikanova M; Patterson D
    Mol Genet Metab; 2013 Mar; 108(3):178-189. PubMed ID: 23394948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenylosuccinate lyase deficiency affects neurobehavior via perturbations to tyramine signaling in Caenorhabditis elegans.
    Moro CA; Sony SA; Franklin LP; Dong S; Peifer MM; Wittig KE; Hanna-Rose W
    PLoS Genet; 2023 Sep; 19(9):e1010974. PubMed ID: 37773959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Caenorhabditis elegans model of adenylosuccinate lyase deficiency reveals neuromuscular and reproductive phenotypes of distinct etiology.
    Fenton AR; Janowitz HN; Franklin LP; Young RG; Moro CA; DeGennaro MV; McReynolds MR; Wang W; Hanna-Rose W
    Mol Genet Metab; 2023 Nov; 140(3):107686. PubMed ID: 37607437
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation.
    Mazzarino RC; Baresova V; Zikánová M; Duval N; Wilkinson TG; Patterson D; Vacano GN
    Mol Genet Metab Rep; 2019 Dec; 21():100512. PubMed ID: 31516833
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mapping of the bovine genes of the de novo AMP synthesis pathway.
    Bønsdorff T; Gautier M; Farstad W; Rønningen K; Lingaas F; Olsaker I
    Anim Genet; 2004 Dec; 35(6):438-44. PubMed ID: 15566465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
    Toth EA; Yeates TO
    Structure; 2000 Feb; 8(2):163-74. PubMed ID: 10673438
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.