These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 35849876)

  • 21. Scutellaria barbata D. Don inhibits colorectal cancer growth via suppression of Wnt/β-catenin signaling pathway.
    Wei LH; Lin JM; Chu JF; Chen HW; Li QY; Peng J
    Chin J Integr Med; 2017 Nov; 23(11):858-863. PubMed ID: 29080197
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Tankyrase inhibitors as antitumor agents: a patent update (2013 - 2020).
    Mehta CC; Bhatt HG
    Expert Opin Ther Pat; 2021 Jul; 31(7):645-661. PubMed ID: 33567917
    [TBL] [Abstract][Full Text] [Related]  

  • 23. USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.
    Novellasdemunt L; Foglizzo V; Cuadrado L; Antas P; Kucharska A; Encheva V; Snijders AP; Li VSW
    Cell Rep; 2017 Oct; 21(3):612-627. PubMed ID: 29045831
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance.
    Quackenbush KS; Bagby S; Tai WM; Messersmith WA; Schreiber A; Greene J; Kim J; Wang G; Purkey A; Pitts TM; Nguyen A; Gao D; Blatchford P; Capasso A; Schuller AG; Eckhardt SG; Arcaroli JJ
    Oncotarget; 2016 May; 7(19):28273-85. PubMed ID: 27070088
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.
    Bao R; Christova T; Song S; Angers S; Yan X; Attisano L
    PLoS One; 2012; 7(11):e48670. PubMed ID: 23144924
    [TBL] [Abstract][Full Text] [Related]  

  • 26. TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer.
    Solberg NT; Waaler J; Lund K; Mygland L; Olsen PA; Krauss S
    Mol Cancer Res; 2018 Mar; 16(3):543-553. PubMed ID: 29222171
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Survival of APC-mutant colorectal cancer cells requires interaction between tankyrase and a thiol peroxidase, peroxiredoxin II.
    Kang DH; Lee JHS; Kang SW
    BMB Rep; 2017 Aug; 50(8):391-392. PubMed ID: 28683851
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase.
    Jang MK; Mashima T; Seimiya H
    Mol Cancer Ther; 2020 Mar; 19(3):765-776. PubMed ID: 31907221
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models.
    Brinch SA; Amundsen-Isaksen E; Espada S; Hammarström C; Aizenshtadt A; Olsen PA; Holmen L; Høyem M; Scholz H; Grødeland G; Sowa ST; Galera-Prat A; Lehtiö L; Meerts IATM; Leenders RGG; Wegert A; Krauss S; Waaler J
    Cancer Res Commun; 2022 Apr; 2(4):233-245. PubMed ID: 36873622
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.
    Wang Z; Tacchelly-Benites O; Yang E; Thorne CA; Nojima H; Lee E; Ahmed Y
    Genetics; 2016 May; 203(1):269-81. PubMed ID: 26975665
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
    Hua Z; Bregman H; Buchanan JL; Chakka N; Guzman-Perez A; Gunaydin H; Huang X; Gu Y; Berry V; Liu J; Teffera Y; Huang L; Egge B; Emkey R; Mullady EL; Schneider S; Andrews PS; Acquaviva L; Dovey J; Mishra A; Newcomb J; Saffran D; Serafino R; Strathdee CA; Turci SM; Stanton M; Wilson C; Dimauro EF
    J Med Chem; 2013 Dec; 56(24):10003-15. PubMed ID: 24294969
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1.
    Zhong Y; Katavolos P; Nguyen T; Lau T; Boggs J; Sambrone A; Kan D; Merchant M; Harstad E; Diaz D; Costa M; Schutten M
    Toxicol Pathol; 2016 Feb; 44(2):267-78. PubMed ID: 26692561
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The tankyrase inhibitor G007-LK inhibits small intestine LGR5
    Norum JH; Skarpen E; Brech A; Kuiper R; Waaler J; Krauss S; Sørlie T
    Biol Res; 2018 Jan; 51(1):3. PubMed ID: 29316982
    [TBL] [Abstract][Full Text] [Related]  

  • 34. MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer.
    Zhang Y; Guo L; Li Y; Feng GH; Teng F; Li W; Zhou Q
    Mol Cancer; 2018 Jan; 17(1):1. PubMed ID: 29304823
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin.
    Freeman TJ; Smith JJ; Chen X; Washington MK; Roland JT; Means AL; Eschrich SA; Yeatman TJ; Deane NG; Beauchamp RD
    Gastroenterology; 2012 Mar; 142(3):562-571.e2. PubMed ID: 22115830
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Evidence for tankyrases as antineoplastic targets in lung cancer.
    Busch AM; Johnson KC; Stan RV; Sanglikar A; Ahmed Y; Dmitrovsky E; Freemantle SJ
    BMC Cancer; 2013 Apr; 13():211. PubMed ID: 23621985
    [TBL] [Abstract][Full Text] [Related]  

  • 37. USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development.
    Novellasdemunt L; Kucharska A; Baulies A; Hutton C; Vlachogiannis G; Repana D; Rowan A; Suárez-Bonnet A; Ciccarelli F; Valeri N; Li VSW
    Stem Cell Reports; 2023 Feb; 18(2):570-584. PubMed ID: 36669491
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1.
    Jain MR; Mohapatra J; Bandhyopadhyay D; Chatterjee A; Ghoshdastidar K; Patel D; Patel A; Bhayani H; Srivastava BK; Shedage SA; Kadam P; Sundar R; Patel H; Giri P; Patel P; Gupta L; Srinivas NR; Patel PR; Desai RC
    Cancer Chemother Pharmacol; 2018 Oct; 82(4):635-647. PubMed ID: 30046848
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.
    Pedersen NM; Thorvaldsen TE; Schultz SW; Wenzel EM; Stenmark H
    PLoS One; 2016; 11(8):e0160507. PubMed ID: 27482906
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.
    Peng K; Kou L; Yu L; Bai C; Li M; Mo P; Li W; Yu C
    Gastroenterology; 2019 Mar; 156(4):1112-1126. PubMed ID: 30472235
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.