166 related articles for article (PubMed ID: 35858546)
1. PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis.
Cotton JL; Dang K; Hu L; Sun Y; Singh A; Rajurkar MS; Li Q; Wu X; Mao J
Cell Rep; 2022 Jul; 40(3):111125. PubMed ID: 35858546
[TBL] [Abstract][Full Text] [Related]
2. Cellular and molecular characteristics of stromal Lkb1 deficiency-induced gastrointestinal polyposis based on single-cell RNA sequencing.
Cai Z; Jiang Y; Tong H; Liang M; Huang Y; Fang L; Liang F; Hu Y; Shi X; Wang J; Wang Z; Ji Q; Huo H; Shen L; He B
J Pathol; 2024 May; 263(1):47-60. PubMed ID: 38389501
[TBL] [Abstract][Full Text] [Related]
3. Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model.
Wei C; Amos CI; Zhang N; Zhu J; Wang X; Frazier ML
Cancer Lett; 2009 May; 277(2):149-54. PubMed ID: 19147279
[TBL] [Abstract][Full Text] [Related]
4. Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes.
Wang ZJ; Taylor F; Churchman M; Norbury G; Tomlinson I
Am J Pathol; 1998 Aug; 153(2):363-6. PubMed ID: 9708796
[TBL] [Abstract][Full Text] [Related]
5. Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.
Bardeesy N; Sinha M; Hezel AF; Signoretti S; Hathaway NA; Sharpless NE; Loda M; Carrasco DR; DePinho RA
Nature; 2002 Sep; 419(6903):162-7. PubMed ID: 12226664
[TBL] [Abstract][Full Text] [Related]
6. Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder.
Shorning BY; Griffiths D; Clarke AR
PLoS One; 2011 Jan; 6(1):e16209. PubMed ID: 21283818
[TBL] [Abstract][Full Text] [Related]
7. Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.
Rossi DJ; Ylikorkala A; Korsisaari N; Salovaara R; Luukko K; Launonen V; Henkemeyer M; Ristimaki A; Aaltonen LA; Makela TP
Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12327-32. PubMed ID: 12218179
[TBL] [Abstract][Full Text] [Related]
8. Evidence for an hMSH3 defect in familial hamartomatous polyps.
Huang SC; Lee JK; Smith EJ; Doctolero RT; Tajima A; Beck SE; Weidner N; Carethers JM
Cancer; 2011 Feb; 117(3):492-500. PubMed ID: 20845481
[TBL] [Abstract][Full Text] [Related]
9. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Huang X; Wullschleger S; Shpiro N; McGuire VA; Sakamoto K; Woods YL; McBurnie W; Fleming S; Alessi DR
Biochem J; 2008 Jun; 412(2):211-21. PubMed ID: 18387000
[TBL] [Abstract][Full Text] [Related]
10. The LKB1 tumor suppressor negatively regulates mTOR signaling.
Shaw RJ; Bardeesy N; Manning BD; Lopez L; Kosmatka M; DePinho RA; Cantley LC
Cancer Cell; 2004 Jul; 6(1):91-9. PubMed ID: 15261145
[TBL] [Abstract][Full Text] [Related]
11. Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis.
Sweet K; Willis J; Zhou XP; Gallione C; Sawada T; Alhopuro P; Khoo SK; Patocs A; Martin C; Bridgeman S; Heinz J; Pilarski R; Lehtonen R; Prior TW; Frebourg T; Teh BT; Marchuk DA; Aaltonen LA; Eng C
JAMA; 2005 Nov; 294(19):2465-73. PubMed ID: 16287957
[TBL] [Abstract][Full Text] [Related]
12. Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome.
Miyaki M; Iijima T; Hosono K; Ishii R; Yasuno M; Mori T; Toi M; Hishima T; Shitara N; Tamura K; Utsunomiya J; Kobayashi N; Kuroki T; Iwama T
Cancer Res; 2000 Nov; 60(22):6311-3. PubMed ID: 11103790
[TBL] [Abstract][Full Text] [Related]
13. Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression.
Ma Y; Zhang G; Fu X; Xia O; Zhan C; Li L; Wang Z; Wu B
Oncol Rep; 2010 Jun; 23(6):1569-76. PubMed ID: 20428811
[TBL] [Abstract][Full Text] [Related]
14. Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis.
Wei C; Amos CI; Stephens LC; Campos I; Deng JM; Behringer RR; Rashid A; Frazier ML
Cancer Res; 2005 Dec; 65(24):11297-303. PubMed ID: 16357136
[TBL] [Abstract][Full Text] [Related]
15. Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice.
Miyoshi H; Nakau M; Ishikawa TO; Seldin MF; Oshima M; Taketo MM
Cancer Res; 2002 Apr; 62(8):2261-6. PubMed ID: 11956081
[TBL] [Abstract][Full Text] [Related]
16. mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome.
Shackelford DB; Vasquez DS; Corbeil J; Wu S; Leblanc M; Wu CL; Vera DR; Shaw RJ
Proc Natl Acad Sci U S A; 2009 Jul; 106(27):11137-42. PubMed ID: 19541609
[TBL] [Abstract][Full Text] [Related]
17. LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes.
Mehenni H; Lin-Marq N; Buchet-Poyau K; Reymond A; Collart MA; Picard D; Antonarakis SE
Hum Mol Genet; 2005 Aug; 14(15):2209-19. PubMed ID: 15987703
[TBL] [Abstract][Full Text] [Related]
18. PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes
Makker A; Goel MM; Mahdi AA; Bhatia V; Das V; Agarwal A; Pandey A
Indian J Med Res; 2016 May; 143(Supplement):S112-S119. PubMed ID: 27748285
[TBL] [Abstract][Full Text] [Related]
19. N-methylnitrosourea aggravates gastrointestinal polyposis in Lkb1+/- mice.
Udd L; Gao Y; Ristimäki AP; Mäkelä TP
Carcinogenesis; 2013 Oct; 34(10):2409-14. PubMed ID: 23722652
[TBL] [Abstract][Full Text] [Related]
20. Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
Tanwar PS; Kaneko-Tarui T; Zhang L; Tanaka Y; Crum CP; Teixeira JM
PLoS Genet; 2012; 8(8):e1002906. PubMed ID: 22916036
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
