BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

39 related articles for article (PubMed ID: 35860875)

  • 1. Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis.
    Park E; Park S; Lee SJ; Jeong D; Jin H; Moon H; Cha B; Kim D; Ma S; Seo W; Han SH; Lee YS; Kang S
    J Med Chem; 2023 Dec; 66(23):16342-16363. PubMed ID: 38031930
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural optimizations on the 7H-pyrrolo[2,3-d]pyrimidine scaffold to develop highly selective, safe and potent JAK3 inhibitors for the treatment of Rheumatoid arthritis.
    He L; Zhang J; Ling Z; Zeng X; Yao H; Tang M; Huang H; Xie X; Qin T; Feng X; Chen Z; Deng F; Yue X
    Bioorg Chem; 2024 Aug; 149():107499. PubMed ID: 38815476
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter.
    Hossain MM; Khalid A; Akhter Z; Parveen S; Ayaz MO; Bhat AQ; Badesra N; Showket F; Dar MS; Ahmed F; Dhiman S; Kumar M; Singh U; Hussain R; Keshari P; Mustafa G; Nargorta A; Taneja N; Gupta S; Mir RA; Kshatri AS; Nandi U; Khan N; Ramajayan P; Yadav G; Ahmed Z; Singh PP; Dar MJ
    J Transl Med; 2024 Apr; 22(1):370. PubMed ID: 38637842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacophore and Virtual Screening of JAK3 inhibitors.
    Rajeswari M; Santhi N; Bhuvaneswari V
    Bioinformation; 2014; 10(3):157-63. PubMed ID: 24748756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-Based Drug Design of Novel Triaminotriazine Derivatives as Orally Bioavailable IDH2
    Wei Q; Yao K; Yang J; Zhou Q; Liu P; Chen J; Liu H; Lai Y; Cao P
    J Med Chem; 2023 Sep; 66(18):12894-12910. PubMed ID: 37706660
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inherent Fluorescence Demonstrates Immunotropic Properties for Novel Janus Kinase 3 Inhibitors.
    Laux J; Martorelli M; Strass S; Schollmeyer D; Maier F; Burnet M; Laufer SA
    ACS Pharmacol Transl Sci; 2023 Oct; 6(10):1433-1452. PubMed ID: 37854620
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A hybrid energy-based and AI-based screening approach for the discovery of novel inhibitors of JAK3.
    Wei J; Pan Y; Shen Z; Shen L; Xu L; Yu W; Huang W
    Front Med (Lausanne); 2023; 10():1182227. PubMed ID: 37886358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Incorporation of an Isohexide Subunit Improves the Drug-like Properties of Bioactive Compounds.
    Sidduri A; Dresel MJ; Knapp S
    ACS Med Chem Lett; 2023 Feb; 14(2):176-182. PubMed ID: 36793427
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.
    Dymock BW; See CS
    Expert Opin Ther Pat; 2013 Apr; 23(4):449-501. PubMed ID: 23367873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. JAK3 inhibitors for the treatment of inflammatory and autoimmune diseases: a patent review (2016-present).
    Chen C; Lu D; Sun T; Zhang T
    Expert Opin Ther Pat; 2022 Mar; 32(3):225-242. PubMed ID: 34949146
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of Hexahydrofuro[3,2-
    Li S; Si H; Song X; Lei C; He X; Wang J; Liu Y; Zhou Y; Song JG; Peng L; Tang X; Chan S; Ren X; Tu Z; Li Z; Wang Z; Zhang Z; Ding K
    J Med Chem; 2022 Aug; 65(15):10674-10690. PubMed ID: 35860875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and structure-activity relationship studies of pyrido[2,3-d]pyrimidin-7-ones as potent Janus Kinase 3 (JAK3) covalent inhibitors.
    Su W; Chen Z; Liu M; He R; Liu C; Li R; Gao M; Zheng M; Tu Z; Zhang Z; Xu T
    Bioorg Med Chem Lett; 2022 May; 64():128680. PubMed ID: 35306167
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors.
    Duan JJ; Lu Z; Jiang B; Yang BV; Doweyko LM; Nirschl DS; Haque LE; Lin S; Brown G; Hynes J; Tokarski JS; Sack JS; Khan J; Lippy JS; Zhang RF; Pitt S; Shen G; Pitts WJ; Carter PH; Barrish JC; Nadler SG; Salter-Cid LM; McKinnon M; Fura A; Schieven GL; Wrobleski ST
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5721-5726. PubMed ID: 25453808
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis.
    Pei H; He L; Shao M; Yang Z; Ran Y; Li D; Zhou Y; Tang M; Wang T; Gong Y; Chen X; Yang S; Xiang M; Chen L
    Sci Rep; 2018 Mar; 8(1):5273. PubMed ID: 29588471
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 16.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 17.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 18.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 2.